| Motif | RFX3.H12INVITRO.0.PSM.A |
| Gene (human) | RFX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx3 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | RFX3.H12INVITRO.0.PSM.A |
| Gene (human) | RFX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx3 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 19 |
| Consensus | nbbGTTGCCATGGhWMYvn |
| GC content | 53.1% |
| Information content (bits; total / per base) | 20.087 / 1.057 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2255 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (7) | 0.958 | 0.961 | 0.929 | 0.934 | 0.943 | 0.947 | 5.92 | 6.029 | 672.721 | 680.921 |
| Mouse | 1 (5) | 0.959 | 0.96 | 0.933 | 0.934 | 0.947 | 0.948 | 6.153 | 6.183 | 705.051 | 790.678 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.705 | 0.722 | 0.586 | 0.611 | 0.537 | 0.561 |
| best | 1 | 1 | 1.0 | 1.0 | 0.932 | 0.941 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.932 | 0.941 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.932 | 0.941 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.633 | 0.652 | 0.554 | 0.573 | 0.522 | 0.539 |
| best | 1 | 1 | 1.0 | 1.0 | 0.895 | 0.91 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.779 | 0.423 | 0.803 | 0.624 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | RFX {3.3.3} (TFClass) |
| TF subfamily | {3.3.3.0} (TFClass) |
| TFClass ID | TFClass: 3.3.3.0.3 |
| HGNC | HGNC:9984 |
| MGI | MGI:106582 |
| EntrezGene (human) | GeneID:5991 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:19726 (SSTAR profile) |
| UniProt ID (human) | RFX3_HUMAN |
| UniProt ID (mouse) | RFX3_MOUSE |
| UniProt AC (human) | P48380 (TFClass) |
| UniProt AC (mouse) | P48381 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 1 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | RFX3.H12INVITRO.0.PSM.A.pcm |
| PWM | RFX3.H12INVITRO.0.PSM.A.pwm |
| PFM | RFX3.H12INVITRO.0.PSM.A.pfm |
| Alignment | RFX3.H12INVITRO.0.PSM.A.words.tsv |
| Threshold to P-value map | RFX3.H12INVITRO.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | RFX3.H12INVITRO.0.PSM.A_jaspar_format.txt |
| MEME format | RFX3.H12INVITRO.0.PSM.A_meme_format.meme |
| Transfac format | RFX3.H12INVITRO.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 514.75 | 777.75 | 432.75 | 529.75 |
| 02 | 284.75 | 807.75 | 544.75 | 617.75 |
| 03 | 181.0 | 1064.0 | 680.0 | 330.0 |
| 04 | 0.0 | 15.0 | 2237.0 | 3.0 |
| 05 | 2.0 | 1.0 | 0.0 | 2252.0 |
| 06 | 20.0 | 2.0 | 0.0 | 2233.0 |
| 07 | 179.0 | 3.0 | 2060.0 | 13.0 |
| 08 | 0.0 | 2234.0 | 6.0 | 15.0 |
| 09 | 0.0 | 1637.0 | 0.0 | 618.0 |
| 10 | 2249.0 | 2.0 | 2.0 | 2.0 |
| 11 | 16.0 | 1.0 | 63.0 | 2175.0 |
| 12 | 127.0 | 4.0 | 2121.0 | 3.0 |
| 13 | 180.0 | 63.0 | 2007.0 | 5.0 |
| 14 | 369.0 | 779.0 | 129.0 | 978.0 |
| 15 | 1342.0 | 45.0 | 399.0 | 469.0 |
| 16 | 1704.0 | 213.0 | 206.0 | 132.0 |
| 17 | 180.0 | 1618.0 | 113.0 | 344.0 |
| 18 | 679.0 | 504.0 | 791.0 | 281.0 |
| 19 | 668.5 | 479.5 | 710.5 | 396.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.228 | 0.345 | 0.192 | 0.235 |
| 02 | 0.126 | 0.358 | 0.242 | 0.274 |
| 03 | 0.08 | 0.472 | 0.302 | 0.146 |
| 04 | 0.0 | 0.007 | 0.992 | 0.001 |
| 05 | 0.001 | 0.0 | 0.0 | 0.999 |
| 06 | 0.009 | 0.001 | 0.0 | 0.99 |
| 07 | 0.079 | 0.001 | 0.914 | 0.006 |
| 08 | 0.0 | 0.991 | 0.003 | 0.007 |
| 09 | 0.0 | 0.726 | 0.0 | 0.274 |
| 10 | 0.997 | 0.001 | 0.001 | 0.001 |
| 11 | 0.007 | 0.0 | 0.028 | 0.965 |
| 12 | 0.056 | 0.002 | 0.941 | 0.001 |
| 13 | 0.08 | 0.028 | 0.89 | 0.002 |
| 14 | 0.164 | 0.345 | 0.057 | 0.434 |
| 15 | 0.595 | 0.02 | 0.177 | 0.208 |
| 16 | 0.756 | 0.094 | 0.091 | 0.059 |
| 17 | 0.08 | 0.718 | 0.05 | 0.153 |
| 18 | 0.301 | 0.224 | 0.351 | 0.125 |
| 19 | 0.296 | 0.213 | 0.315 | 0.176 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.091 | 0.321 | -0.263 | -0.062 |
| 02 | -0.68 | 0.359 | -0.034 | 0.091 |
| 03 | -1.129 | 0.634 | 0.187 | -0.533 |
| 04 | -5.68 | -3.509 | 1.376 | -4.743 |
| 05 | -4.969 | -5.263 | -5.68 | 1.382 |
| 06 | -3.25 | -4.969 | -5.68 | 1.374 |
| 07 | -1.14 | -4.743 | 1.293 | -3.635 |
| 08 | -5.68 | 1.374 | -4.267 | -3.509 |
| 09 | -5.68 | 1.064 | -5.68 | 0.092 |
| 10 | 1.381 | -4.969 | -4.969 | -4.969 |
| 11 | -3.452 | -5.263 | -2.165 | 1.348 |
| 12 | -1.479 | -4.558 | 1.323 | -4.743 |
| 13 | -1.134 | -2.165 | 1.267 | -4.402 |
| 14 | -0.422 | 0.322 | -1.463 | 0.549 |
| 15 | 0.865 | -2.489 | -0.344 | -0.183 |
| 16 | 1.104 | -0.968 | -1.001 | -1.441 |
| 17 | -1.134 | 1.052 | -1.594 | -0.492 |
| 18 | 0.185 | -0.112 | 0.338 | -0.693 |
| 19 | 0.17 | -0.161 | 0.231 | -0.35 |
| P-value | Threshold |
|---|---|
| 0.001 | -1.68074 |
| 0.0005 | 0.05601 |
| 0.0001 | 3.71186 |