MotifRFX3.H12CORE.2.S.B
Gene (human)RFX3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length20
ConsensusddKKKGTAGGKWRGGRdKdd
GC content56.89%
Information content (bits; total / per base)17.086 / 0.854
Data sourcesHT-SELEX
Aligned words535

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.483 0.489 0.323 0.326 0.591 0.596 1.479 1.507 0 0
Mouse 1 (5) 0.519 0.52 0.346 0.347 0.62 0.628 1.65 1.682 0 0

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.57 0.545 0.535 0.526 0.511 0.513
best 0.776 0.754 0.626 0.639 0.546 0.575
Methyl HT-SELEX, 1 experiments median 0.587 0.553 0.551 0.536 0.511 0.518
best 0.587 0.553 0.551 0.536 0.511 0.518
Non-Methyl HT-SELEX, 5 experiments median 0.553 0.538 0.519 0.515 0.51 0.507
best 0.776 0.754 0.626 0.639 0.546 0.575

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.4 0.018 -0.116 -0.134
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.3
HGNCHGNC:9984
MGIMGI:106582
EntrezGene (human)GeneID:5991
(SSTAR profile)
EntrezGene (mouse)GeneID:19726
(SSTAR profile)
UniProt ID (human)RFX3_HUMAN
UniProt ID (mouse)RFX3_MOUSE
UniProt AC (human)P48380
(TFClass)
UniProt AC (mouse)P48381
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
0190.2577.25234.25133.25
02130.057.0220.0128.0
0335.025.0408.067.0
0439.028.0109.0359.0
0513.08.0177.0337.0
0616.05.0488.026.0
074.01.0164.0366.0
08505.02.010.018.0
090.01.0532.02.0
100.00.0531.04.0
1117.07.0210.0301.0
12119.018.088.0310.0
13326.07.0164.038.0
1436.07.0477.015.0
1528.05.0491.011.0
1693.043.0342.057.0
17216.046.0211.062.0
1894.019.0290.0132.0
1974.2534.25289.25137.25
2095.561.5199.5178.5
PFM
ACGT
010.1690.1440.4380.249
020.2430.1070.4110.239
030.0650.0470.7630.125
040.0730.0520.2040.671
050.0240.0150.3310.63
060.030.0090.9120.049
070.0070.0020.3070.684
080.9440.0040.0190.034
090.00.0020.9940.004
100.00.00.9930.007
110.0320.0130.3930.563
120.2220.0340.1640.579
130.6090.0130.3070.071
140.0670.0130.8920.028
150.0520.0090.9180.021
160.1740.080.6390.107
170.4040.0860.3940.116
180.1760.0360.5420.247
190.1390.0640.5410.257
200.1790.1150.3730.334
PWM
ACGT
01-0.388-0.540.555-0.004
02-0.028-0.8370.493-0.043
03-1.308-1.6281.107-0.68
04-1.205-1.521-0.2020.98
05-2.229-2.6490.2770.917
06-2.041-3.0251.286-1.591
07-3.19-3.9640.2020.999
081.32-3.635-2.459-1.934
09-4.456-3.9641.372-3.635
10-4.456-4.4561.37-3.19
11-1.986-2.7590.4470.805
12-0.115-1.934-0.4130.834
130.884-2.7590.202-1.23
14-1.281-2.7591.263-2.1
15-1.521-3.0251.292-2.376
16-0.358-1.1110.932-0.837
170.475-1.0450.452-0.755
18-0.348-1.8840.768-0.013
19-0.579-1.3290.7650.026
20-0.332-0.7630.3960.286
Standard thresholds
P-value Threshold
0.001 2.20291
0.0005 3.44996
0.0001 6.06286