| Motif | RFX3.H12CORE.2.S.B |
| Gene (human) | RFX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx3 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | RFX3.H12CORE.2.S.B |
| Gene (human) | RFX3 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx3 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 20 |
| Consensus | ddKKKGTAGGKWRGGRdKdd |
| GC content | 56.89% |
| Information content (bits; total / per base) | 17.086 / 0.854 |
| Data sources | HT-SELEX |
| Aligned words | 535 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (7) | 0.483 | 0.489 | 0.323 | 0.326 | 0.591 | 0.596 | 1.479 | 1.507 | 0 | 0 |
| Mouse | 1 (5) | 0.519 | 0.52 | 0.346 | 0.347 | 0.62 | 0.628 | 1.65 | 1.682 | 0 | 0 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.57 | 0.545 | 0.535 | 0.526 | 0.511 | 0.513 |
| best | 0.776 | 0.754 | 0.626 | 0.639 | 0.546 | 0.575 | |
| Methyl HT-SELEX, 1 experiments | median | 0.587 | 0.553 | 0.551 | 0.536 | 0.511 | 0.518 |
| best | 0.587 | 0.553 | 0.551 | 0.536 | 0.511 | 0.518 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.553 | 0.538 | 0.519 | 0.515 | 0.51 | 0.507 |
| best | 0.776 | 0.754 | 0.626 | 0.639 | 0.546 | 0.575 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.4 | 0.018 | -0.116 | -0.134 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | RFX {3.3.3} (TFClass) |
| TF subfamily | {3.3.3.0} (TFClass) |
| TFClass ID | TFClass: 3.3.3.0.3 |
| HGNC | HGNC:9984 |
| MGI | MGI:106582 |
| EntrezGene (human) | GeneID:5991 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:19726 (SSTAR profile) |
| UniProt ID (human) | RFX3_HUMAN |
| UniProt ID (mouse) | RFX3_MOUSE |
| UniProt AC (human) | P48380 (TFClass) |
| UniProt AC (mouse) | P48381 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 1 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | RFX3.H12CORE.2.S.B.pcm |
| PWM | RFX3.H12CORE.2.S.B.pwm |
| PFM | RFX3.H12CORE.2.S.B.pfm |
| Alignment | RFX3.H12CORE.2.S.B.words.tsv |
| Threshold to P-value map | RFX3.H12CORE.2.S.B.thr |
| Motif in other formats | |
| JASPAR format | RFX3.H12CORE.2.S.B_jaspar_format.txt |
| MEME format | RFX3.H12CORE.2.S.B_meme_format.meme |
| Transfac format | RFX3.H12CORE.2.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 90.25 | 77.25 | 234.25 | 133.25 |
| 02 | 130.0 | 57.0 | 220.0 | 128.0 |
| 03 | 35.0 | 25.0 | 408.0 | 67.0 |
| 04 | 39.0 | 28.0 | 109.0 | 359.0 |
| 05 | 13.0 | 8.0 | 177.0 | 337.0 |
| 06 | 16.0 | 5.0 | 488.0 | 26.0 |
| 07 | 4.0 | 1.0 | 164.0 | 366.0 |
| 08 | 505.0 | 2.0 | 10.0 | 18.0 |
| 09 | 0.0 | 1.0 | 532.0 | 2.0 |
| 10 | 0.0 | 0.0 | 531.0 | 4.0 |
| 11 | 17.0 | 7.0 | 210.0 | 301.0 |
| 12 | 119.0 | 18.0 | 88.0 | 310.0 |
| 13 | 326.0 | 7.0 | 164.0 | 38.0 |
| 14 | 36.0 | 7.0 | 477.0 | 15.0 |
| 15 | 28.0 | 5.0 | 491.0 | 11.0 |
| 16 | 93.0 | 43.0 | 342.0 | 57.0 |
| 17 | 216.0 | 46.0 | 211.0 | 62.0 |
| 18 | 94.0 | 19.0 | 290.0 | 132.0 |
| 19 | 74.25 | 34.25 | 289.25 | 137.25 |
| 20 | 95.5 | 61.5 | 199.5 | 178.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.169 | 0.144 | 0.438 | 0.249 |
| 02 | 0.243 | 0.107 | 0.411 | 0.239 |
| 03 | 0.065 | 0.047 | 0.763 | 0.125 |
| 04 | 0.073 | 0.052 | 0.204 | 0.671 |
| 05 | 0.024 | 0.015 | 0.331 | 0.63 |
| 06 | 0.03 | 0.009 | 0.912 | 0.049 |
| 07 | 0.007 | 0.002 | 0.307 | 0.684 |
| 08 | 0.944 | 0.004 | 0.019 | 0.034 |
| 09 | 0.0 | 0.002 | 0.994 | 0.004 |
| 10 | 0.0 | 0.0 | 0.993 | 0.007 |
| 11 | 0.032 | 0.013 | 0.393 | 0.563 |
| 12 | 0.222 | 0.034 | 0.164 | 0.579 |
| 13 | 0.609 | 0.013 | 0.307 | 0.071 |
| 14 | 0.067 | 0.013 | 0.892 | 0.028 |
| 15 | 0.052 | 0.009 | 0.918 | 0.021 |
| 16 | 0.174 | 0.08 | 0.639 | 0.107 |
| 17 | 0.404 | 0.086 | 0.394 | 0.116 |
| 18 | 0.176 | 0.036 | 0.542 | 0.247 |
| 19 | 0.139 | 0.064 | 0.541 | 0.257 |
| 20 | 0.179 | 0.115 | 0.373 | 0.334 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.388 | -0.54 | 0.555 | -0.004 |
| 02 | -0.028 | -0.837 | 0.493 | -0.043 |
| 03 | -1.308 | -1.628 | 1.107 | -0.68 |
| 04 | -1.205 | -1.521 | -0.202 | 0.98 |
| 05 | -2.229 | -2.649 | 0.277 | 0.917 |
| 06 | -2.041 | -3.025 | 1.286 | -1.591 |
| 07 | -3.19 | -3.964 | 0.202 | 0.999 |
| 08 | 1.32 | -3.635 | -2.459 | -1.934 |
| 09 | -4.456 | -3.964 | 1.372 | -3.635 |
| 10 | -4.456 | -4.456 | 1.37 | -3.19 |
| 11 | -1.986 | -2.759 | 0.447 | 0.805 |
| 12 | -0.115 | -1.934 | -0.413 | 0.834 |
| 13 | 0.884 | -2.759 | 0.202 | -1.23 |
| 14 | -1.281 | -2.759 | 1.263 | -2.1 |
| 15 | -1.521 | -3.025 | 1.292 | -2.376 |
| 16 | -0.358 | -1.111 | 0.932 | -0.837 |
| 17 | 0.475 | -1.045 | 0.452 | -0.755 |
| 18 | -0.348 | -1.884 | 0.768 | -0.013 |
| 19 | -0.579 | -1.329 | 0.765 | 0.026 |
| 20 | -0.332 | -0.763 | 0.396 | 0.286 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.20291 |
| 0.0005 | 3.44996 |
| 0.0001 | 6.06286 |