MotifRFX3.H12CORE.0.PSM.A
Gene (human)RFX3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length14
ConsensusGTTGCCddGRnRMY
GC content56.71%
Information content (bits; total / per base)14.389 / 1.028
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words862

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.971 0.974 0.946 0.949 0.961 0.965 6.003 6.047 747.658 760.886
Mouse 1 (5) 0.975 0.977 0.955 0.957 0.965 0.967 6.284 6.309 791.032 891.237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.717 0.738 0.587 0.617 0.536 0.564
best 1.0 1.0 1.0 1.0 0.93 0.94
Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 1.0 0.93 0.94
best 1.0 1.0 1.0 1.0 0.93 0.94
Non-Methyl HT-SELEX, 5 experiments median 0.656 0.682 0.564 0.588 0.53 0.549
best 1.0 1.0 1.0 1.0 0.891 0.908

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.777 0.375 0.772 0.565
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.3
HGNCHGNC:9984
MGIMGI:106582
EntrezGene (human)GeneID:5991
(SSTAR profile)
EntrezGene (mouse)GeneID:19726
(SSTAR profile)
UniProt ID (human)RFX3_HUMAN
UniProt ID (mouse)RFX3_MOUSE
UniProt AC (human)P48380
(TFClass)
UniProt AC (mouse)P48381
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 1 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
017.05.0849.01.0
025.033.04.0820.0
0316.084.013.0749.0
0475.07.0728.052.0
050.0803.03.056.0
066.0620.03.0233.0
07663.047.076.076.0
08138.040.0207.0477.0
0938.09.0805.010.0
10117.068.0663.014.0
11239.0292.0199.0132.0
12431.054.0309.068.0
13596.0171.062.033.0
1470.0621.069.0102.0
PFM
ACGT
010.0080.0060.9850.001
020.0060.0380.0050.951
030.0190.0970.0150.869
040.0870.0080.8450.06
050.00.9320.0030.065
060.0070.7190.0030.27
070.7690.0550.0880.088
080.160.0460.240.553
090.0440.010.9340.012
100.1360.0790.7690.016
110.2770.3390.2310.153
120.50.0630.3580.079
130.6910.1980.0720.038
140.0810.720.080.118
PWM
ACGT
01-3.219-3.481.365-4.391
02-3.48-1.834-3.6421.331
03-2.508-0.93-2.6941.24
04-1.041-3.2191.212-1.398
05-4.8561.31-3.835-1.326
06-3.3411.052-3.8350.077
071.119-1.495-1.028-1.028
08-0.441-1.651-0.040.79
09-1.7-3.0111.312-2.922
10-0.604-1.1371.119-2.628
110.1030.302-0.079-0.485
120.689-1.3610.358-1.137
131.012-0.229-1.227-1.834
14-1.1081.053-1.122-0.739
Standard thresholds
P-value Threshold
0.001 3.32466
0.0005 4.44571
0.0001 6.75341