MotifRFX2.H12CORE.1.PSM.A
Gene (human)RFX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length16
ConsensusbGTTRCCATGGhdAYn
GC content49.66%
Information content (bits; total / per base)17.695 / 1.106
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9788

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (13) 0.845 0.951 0.825 0.919 0.866 0.94 5.525 5.857 70.959 496.538
Mouse 2 (14) 0.963 0.979 0.941 0.966 0.961 0.982 7.09 8.009 357.146 593.276

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 1.0 0.999 0.869 0.881 0.694 0.733
best 1 1 1.0 1.0 1.0 1.0
Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 1.0 0.956 0.959
best 1.0 1.0 1.0 1.0 0.956 0.959
Non-Methyl HT-SELEX, 5 experiments median 0.999 0.999 0.851 0.869 0.675 0.72
best 1 1 1.0 1.0 1.0 1.0

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.901 0.485 0.864 0.514
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.2
HGNCHGNC:9983
MGIMGI:106583
EntrezGene (human)GeneID:5990
(SSTAR profile)
EntrezGene (mouse)GeneID:19725
(SSTAR profile)
UniProt ID (human)RFX2_HUMAN
UniProt ID (mouse)RFX2_MOUSE
UniProt AC (human)P48378
(TFClass)
UniProt AC (mouse)P48379
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
011396.53884.52832.51674.5
0237.7542.759674.7532.75
0325.087.032.09644.0
04629.054.07.09098.0
052674.017.06451.0646.0
061.09019.06.0762.0
070.06936.023.02829.0
089534.025.0110.0119.0
09440.091.0307.08950.0
101161.057.08348.0222.0
11943.0373.08400.072.0
121773.02740.01157.04118.0
134924.0526.01765.02573.0
148829.0405.0218.0336.0
15767.757787.75175.751056.75
161951.52813.53406.51616.5
PFM
ACGT
010.1430.3970.2890.171
020.0040.0040.9880.003
030.0030.0090.0030.985
040.0640.0060.0010.93
050.2730.0020.6590.066
060.00.9210.0010.078
070.00.7090.0020.289
080.9740.0030.0110.012
090.0450.0090.0310.914
100.1190.0060.8530.023
110.0960.0380.8580.007
120.1810.280.1180.421
130.5030.0540.180.263
140.9020.0410.0220.034
150.0780.7960.0180.108
160.1990.2870.3480.165
PWM
ACGT
01-0.560.4620.146-0.379
02-4.113-3.9961.374-4.247
03-4.497-3.312-4.2681.371
04-1.356-3.773-5.5741.313
050.089-4.8440.969-1.329
06-6.611.304-5.688-1.165
07-6.9721.041-4.5730.145
081.359-4.497-3.082-3.005
09-1.712-3.268-2.0691.296
10-0.745-3.7211.226-2.391
11-0.952-1.8761.233-3.495
12-0.3220.113-0.7480.52
130.699-1.534-0.3260.05
141.283-1.794-2.409-1.98
15-1.1571.157-2.622-0.838
16-0.2260.1390.331-0.414
Standard thresholds
P-value Threshold
0.001 0.91311
0.0005 2.36566
0.0001 5.39411