MotifRFX1.H12INVITRO.2.S.C
Gene (human)RFX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Rfx1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length11
ConsensusnnSGTTGCYdn
GC content54.69%
Information content (bits; total / per base)11.032 / 1.003
Data sourcesHT-SELEX
Aligned words731

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (35) 0.857 0.892 0.775 0.817 0.766 0.8 2.228 2.419 384.155 515.086
Mouse 4 (20) 0.835 0.855 0.721 0.74 0.749 0.778 2.137 2.247 366.235 424.143

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.958 0.94 0.88 0.864 0.782 0.775
best 0.985 0.977 0.976 0.962 0.919 0.905
Methyl HT-SELEX, 2 experiments median 0.899 0.86 0.838 0.81 0.764 0.744
best 0.97 0.951 0.956 0.931 0.879 0.857
Non-Methyl HT-SELEX, 2 experiments median 0.966 0.953 0.89 0.88 0.802 0.799
best 0.985 0.977 0.976 0.962 0.919 0.905

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 2.369 6.321 0.131 0.052

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.666 0.193 0.632 0.457
batch 2 0.618 0.333 0.757 0.52
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classFork head/winged helix factors {3.3} (TFClass)
TF familyRFX {3.3.3} (TFClass)
TF subfamily {3.3.3.0} (TFClass)
TFClass IDTFClass: 3.3.3.0.1
HGNCHGNC:9982
MGIMGI:105982
EntrezGene (human)GeneID:5989
(SSTAR profile)
EntrezGene (mouse)GeneID:19724
(SSTAR profile)
UniProt ID (human)RFX1_HUMAN
UniProt ID (mouse)RFX1_MOUSE
UniProt AC (human)P22670
(TFClass)
UniProt AC (mouse)P48377
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01206.75146.75241.75135.75
02183.25112.25255.25180.25
0328.0317.0311.075.0
040.00.0731.00.0
050.00.05.0726.0
063.00.00.0728.0
073.00.0728.00.0
080.0698.032.01.0
092.0154.081.0494.0
10305.75116.75132.75175.75
11153.75145.75189.75241.75
PFM
ACGT
010.2830.2010.3310.186
020.2510.1540.3490.247
030.0380.4340.4250.103
040.00.01.00.0
050.00.00.0070.993
060.0040.00.00.996
070.0040.00.9960.0
080.00.9550.0440.001
090.0030.2110.1110.676
100.4180.160.1820.24
110.210.1990.260.331
PWM
ACGT
010.122-0.2170.278-0.294
020.003-0.4820.332-0.014
03-1.8280.5470.528-0.878
04-4.717-4.7171.38-4.717
05-4.717-4.717-3.3231.373
06-3.681-4.717-4.7171.375
07-3.681-4.7171.375-4.717
08-4.7171.333-1.701-4.243
09-3.923-0.169-0.8030.989
100.511-0.443-0.316-0.039
11-0.171-0.2240.0370.278
Standard thresholds
P-value Threshold
0.001 3.937165
0.0005 5.727605
0.0001 7.86294