| Motif | RFX1.H12CORE.1.PSM.A |
| Gene (human) | RFX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx1 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | A |
| Motif | RFX1.H12CORE.1.PSM.A |
| Gene (human) | RFX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Rfx1 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | A |
| Motif length | 18 |
| Consensus | bbbGTTGCCAKGGhRACv |
| GC content | 57.09% |
| Information content (bits; total / per base) | 17.66 / 0.981 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 836 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (35) | 0.974 | 0.992 | 0.953 | 0.986 | 0.966 | 0.988 | 6.888 | 8.62 | 680.886 | 939.409 |
| Mouse | 4 (20) | 0.962 | 0.969 | 0.935 | 0.951 | 0.95 | 0.96 | 6.571 | 7.599 | 668.951 | 848.027 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.997 | 0.996 | 0.953 | 0.952 | 0.865 | 0.877 |
| best | 1 | 1 | 1.0 | 1.0 | 0.995 | 0.994 | |
| Methyl HT-SELEX, 2 experiments | median | 0.997 | 0.996 | 0.953 | 0.952 | 0.865 | 0.877 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.99 | 0.99 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.858 | 0.858 | 0.797 | 0.806 | 0.766 | 0.778 |
| best | 1 | 1 | 1.0 | 1.0 | 0.995 | 0.994 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 3.742 | 13.283 | 0.217 | 0.105 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.942 | 0.561 | 0.909 | 0.551 |
| batch 2 | 0.913 | 0.791 | 0.826 | 0.427 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Fork head/winged helix factors {3.3} (TFClass) |
| TF family | RFX {3.3.3} (TFClass) |
| TF subfamily | {3.3.3.0} (TFClass) |
| TFClass ID | TFClass: 3.3.3.0.1 |
| HGNC | HGNC:9982 |
| MGI | MGI:105982 |
| EntrezGene (human) | GeneID:5989 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:19724 (SSTAR profile) |
| UniProt ID (human) | RFX1_HUMAN |
| UniProt ID (mouse) | RFX1_MOUSE |
| UniProt AC (human) | P22670 (TFClass) |
| UniProt AC (mouse) | P48377 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 4 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 2 |
| PCM | RFX1.H12CORE.1.PSM.A.pcm |
| PWM | RFX1.H12CORE.1.PSM.A.pwm |
| PFM | RFX1.H12CORE.1.PSM.A.pfm |
| Alignment | RFX1.H12CORE.1.PSM.A.words.tsv |
| Threshold to P-value map | RFX1.H12CORE.1.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | RFX1.H12CORE.1.PSM.A_jaspar_format.txt |
| MEME format | RFX1.H12CORE.1.PSM.A_meme_format.meme |
| Transfac format | RFX1.H12CORE.1.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 106.0 | 276.0 | 317.0 | 137.0 |
| 02 | 50.0 | 419.0 | 165.0 | 202.0 |
| 03 | 85.0 | 181.0 | 351.0 | 219.0 |
| 04 | 3.0 | 0.0 | 832.0 | 1.0 |
| 05 | 3.0 | 10.0 | 2.0 | 821.0 |
| 06 | 30.0 | 65.0 | 3.0 | 738.0 |
| 07 | 75.0 | 7.0 | 710.0 | 44.0 |
| 08 | 0.0 | 746.0 | 0.0 | 90.0 |
| 09 | 3.0 | 622.0 | 2.0 | 209.0 |
| 10 | 728.0 | 19.0 | 50.0 | 39.0 |
| 11 | 75.0 | 25.0 | 123.0 | 613.0 |
| 12 | 30.0 | 2.0 | 803.0 | 1.0 |
| 13 | 57.0 | 39.0 | 739.0 | 1.0 |
| 14 | 246.0 | 284.0 | 84.0 | 222.0 |
| 15 | 443.0 | 26.0 | 299.0 | 68.0 |
| 16 | 692.0 | 76.0 | 45.0 | 23.0 |
| 17 | 21.0 | 681.0 | 37.0 | 97.0 |
| 18 | 186.0 | 225.0 | 326.0 | 99.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.127 | 0.33 | 0.379 | 0.164 |
| 02 | 0.06 | 0.501 | 0.197 | 0.242 |
| 03 | 0.102 | 0.217 | 0.42 | 0.262 |
| 04 | 0.004 | 0.0 | 0.995 | 0.001 |
| 05 | 0.004 | 0.012 | 0.002 | 0.982 |
| 06 | 0.036 | 0.078 | 0.004 | 0.883 |
| 07 | 0.09 | 0.008 | 0.849 | 0.053 |
| 08 | 0.0 | 0.892 | 0.0 | 0.108 |
| 09 | 0.004 | 0.744 | 0.002 | 0.25 |
| 10 | 0.871 | 0.023 | 0.06 | 0.047 |
| 11 | 0.09 | 0.03 | 0.147 | 0.733 |
| 12 | 0.036 | 0.002 | 0.961 | 0.001 |
| 13 | 0.068 | 0.047 | 0.884 | 0.001 |
| 14 | 0.294 | 0.34 | 0.1 | 0.266 |
| 15 | 0.53 | 0.031 | 0.358 | 0.081 |
| 16 | 0.828 | 0.091 | 0.054 | 0.028 |
| 17 | 0.025 | 0.815 | 0.044 | 0.116 |
| 18 | 0.222 | 0.269 | 0.39 | 0.118 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.671 | 0.276 | 0.414 | -0.418 |
| 02 | -1.405 | 0.692 | -0.234 | -0.034 |
| 03 | -0.888 | -0.143 | 0.515 | 0.046 |
| 04 | -3.807 | -4.83 | 1.376 | -4.364 |
| 05 | -3.807 | -2.892 | -4.047 | 1.362 |
| 06 | -1.895 | -1.15 | -3.807 | 1.256 |
| 07 | -1.011 | -3.189 | 1.217 | -1.529 |
| 08 | -4.83 | 1.267 | -4.83 | -0.832 |
| 09 | -3.807 | 1.085 | -4.047 | 0.0 |
| 10 | 1.242 | -2.321 | -1.405 | -1.645 |
| 11 | -1.011 | -2.066 | -0.525 | 1.071 |
| 12 | -1.895 | -4.047 | 1.34 | -4.364 |
| 13 | -1.278 | -1.645 | 1.257 | -4.364 |
| 14 | 0.162 | 0.305 | -0.9 | 0.06 |
| 15 | 0.747 | -2.03 | 0.356 | -1.106 |
| 16 | 1.192 | -0.998 | -1.507 | -2.144 |
| 17 | -2.229 | 1.176 | -1.695 | -0.758 |
| 18 | -0.116 | 0.073 | 0.442 | -0.738 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.68536 |
| 0.0005 | 3.00796 |
| 0.0001 | 5.77336 |