REST.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	REST.H12RSNP.0.P.B
Gene (human)	REST (GeneCards)
Gene synonyms (human)	NRSF, XBR
Gene (mouse)	Rest
Gene synonyms (mouse)	Nrsf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	21
Consensus	dYYRSbACShhGGACAGMnMM
GC content	58.99%
Information content (bits; total / per base)	18.635 / 0.887
Data sources	ChIP-Seq
Aligned words	744

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	63 (418)	0.965	0.987	0.953	0.979	0.96	0.984	10.352	12.201	629.328	1040.959
Mouse	25 (165)	0.97	0.984	0.953	0.974	0.963	0.98	9.99	10.932	565.553	781.036

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.398	9.168	0.137	0.05

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.27
HGNC	HGNC:9966
MGI	MGI:104897
EntrezGene (human)	GeneID:5978 (SSTAR profile)
EntrezGene (mouse)	GeneID:19712 (SSTAR profile)
UniProt ID (human)	REST_HUMAN
UniProt ID (mouse)	REST_MOUSE
UniProt AC (human)	Q13127 (TFClass)
UniProt AC (mouse)	Q8VIG1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	63 human, 25 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	REST.H12RSNP.0.P.B.pcm
PWM	REST.H12RSNP.0.P.B.pwm
PFM	REST.H12RSNP.0.P.B.pfm
Alignment	REST.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	REST.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	REST.H12RSNP.0.P.B_jaspar_format.txt
MEME format	REST.H12RSNP.0.P.B_meme_format.meme
Transfac format	REST.H12RSNP.0.P.B_transfac_format.txt
Homer format	REST.H12RSNP.0.P.B_homer_format_0.001.txt REST.H12RSNP.0.P.B_homer_format_0.0005.txt REST.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	133.0	117.0	159.0	335.0
02	39.0	164.0	79.0	462.0
03	63.0	570.0	37.0	74.0
04	575.0	40.0	89.0	40.0
05	44.0	88.0	585.0	27.0
06	77.0	418.0	167.0	82.0
07	608.0	32.0	50.0	54.0
08	24.0	649.0	38.0	33.0
09	39.0	599.0	61.0	45.0
10	395.0	120.0	94.0	135.0
11	108.0	155.0	57.0	424.0
12	24.0	18.0	697.0	5.0
13	21.0	24.0	691.0	8.0
14	637.0	35.0	19.0	53.0
15	13.0	610.0	89.0	32.0
16	719.0	7.0	7.0	11.0
17	24.0	7.0	712.0	1.0
18	98.0	510.0	46.0	90.0
19	214.0	12.0	259.0	259.0
20	131.0	457.0	110.0	46.0
21	112.0	524.0	15.0	93.0

PFM

	A	C	G	T
01	0.179	0.157	0.214	0.45
02	0.052	0.22	0.106	0.621
03	0.085	0.766	0.05	0.099
04	0.773	0.054	0.12	0.054
05	0.059	0.118	0.786	0.036
06	0.103	0.562	0.224	0.11
07	0.817	0.043	0.067	0.073
08	0.032	0.872	0.051	0.044
09	0.052	0.805	0.082	0.06
10	0.531	0.161	0.126	0.181
11	0.145	0.208	0.077	0.57
12	0.032	0.024	0.937	0.007
13	0.028	0.032	0.929	0.011
14	0.856	0.047	0.026	0.071
15	0.017	0.82	0.12	0.043
16	0.966	0.009	0.009	0.015
17	0.032	0.009	0.957	0.001
18	0.132	0.685	0.062	0.121
19	0.288	0.016	0.348	0.348
20	0.176	0.614	0.148	0.062
21	0.151	0.704	0.02	0.125

PWM

	A	C	G	T
01	-0.332	-0.458	-0.155	0.584
02	-1.53	-0.125	-0.844	0.905
03	-1.066	1.114	-1.58	-0.908
04	1.123	-1.505	-0.728	-1.505
05	-1.414	-0.739	1.14	-1.879
06	-0.87	0.805	-0.107	-0.808
07	1.178	-1.718	-1.29	-1.215
08	-1.99	1.243	-1.554	-1.689
09	-1.53	1.163	-1.097	-1.392
10	0.748	-0.433	-0.674	-0.317
11	-0.537	-0.181	-1.163	0.819
12	-1.99	-2.256	1.315	-3.34
13	-2.114	-1.99	1.306	-2.967
14	1.225	-1.633	-2.207	-1.234
15	-2.55	1.182	-0.728	-1.718
16	1.346	-3.077	-3.077	-2.697
17	-1.99	-3.077	1.336	-4.259
18	-0.633	1.003	-1.371	-0.717
19	0.139	-2.621	0.329	0.329
20	-0.347	0.894	-0.519	-1.371
21	-0.501	1.03	-2.422	-0.684

Standard thresholds

P-value	Threshold
0.001	2.03501
0.0005	3.21526
0.0001	5.73076