REST.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	REST.H12INVIVO.0.P.B
Gene (human)	REST (GeneCards)
Gene synonyms (human)	NRSF, XBR
Gene (mouse)	Rest
Gene synonyms (mouse)	Nrsf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	21
Consensus	YYRSnRCSvhGGACAGMdMMh
GC content	61.98%
Information content (bits; total / per base)	18.655 / 0.888
Data sources	ChIP-Seq
Aligned words	983

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	63 (418)	0.976	0.994	0.967	0.989	0.972	0.993	10.173	11.971	659.975	1088.538
Mouse	25 (165)	0.981	0.992	0.968	0.984	0.977	0.99	10.001	10.738	593.328	807.046

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.005	8.458	0.131	0.055

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.27
HGNC	HGNC:9966
MGI	MGI:104897
EntrezGene (human)	GeneID:5978 (SSTAR profile)
EntrezGene (mouse)	GeneID:19712 (SSTAR profile)
UniProt ID (human)	REST_HUMAN
UniProt ID (mouse)	REST_MOUSE
UniProt AC (human)	Q13127 (TFClass)
UniProt AC (mouse)	Q8VIG1 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	63 human, 25 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	REST.H12INVIVO.0.P.B.pcm
PWM	REST.H12INVIVO.0.P.B.pwm
PFM	REST.H12INVIVO.0.P.B.pfm
Alignment	REST.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	REST.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	REST.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	REST.H12INVIVO.0.P.B_meme_format.meme
Transfac format	REST.H12INVIVO.0.P.B_transfac_format.txt
Homer format	REST.H12INVIVO.0.P.B_homer_format_0.001.txt REST.H12INVIVO.0.P.B_homer_format_0.0005.txt REST.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	48.25	241.25	123.25	570.25
02	74.25	731.25	60.25	117.25
03	678.25	90.25	137.25	77.25
04	64.25	126.25	754.25	38.25
05	105.25	537.25	235.25	105.25
06	783.25	57.25	84.25	58.25
07	56.25	810.25	64.25	52.25
08	45.25	743.25	107.25	87.25
09	469.25	180.25	177.25	156.25
10	119.25	262.25	69.25	532.25
11	22.25	6.25	946.25	8.25
12	11.25	7.25	955.25	9.25
13	850.25	80.25	19.25	33.25
14	17.25	830.25	120.25	15.25
15	952.25	8.25	13.25	9.25
16	27.0	5.0	947.0	4.0
17	124.0	714.0	64.0	81.0
18	212.0	13.0	378.0	380.0
19	155.0	636.0	150.0	42.0
20	113.0	738.0	25.0	107.0
21	225.0	448.0	97.0	213.0

PFM

	A	C	G	T
01	0.049	0.245	0.125	0.58
02	0.076	0.744	0.061	0.119
03	0.69	0.092	0.14	0.079
04	0.065	0.128	0.767	0.039
05	0.107	0.547	0.239	0.107
06	0.797	0.058	0.086	0.059
07	0.057	0.824	0.065	0.053
08	0.046	0.756	0.109	0.089
09	0.477	0.183	0.18	0.159
10	0.121	0.267	0.07	0.541
11	0.023	0.006	0.963	0.008
12	0.011	0.007	0.972	0.009
13	0.865	0.082	0.02	0.034
14	0.018	0.845	0.122	0.016
15	0.969	0.008	0.013	0.009
16	0.027	0.005	0.963	0.004
17	0.126	0.726	0.065	0.082
18	0.216	0.013	0.385	0.387
19	0.158	0.647	0.153	0.043
20	0.115	0.751	0.025	0.109
21	0.229	0.456	0.099	0.217

PWM

	A	C	G	T
01	-1.6	-0.018	-0.683	0.838
02	-1.181	1.086	-1.385	-0.732
03	1.011	-0.99	-0.577	-1.142
04	-1.322	-0.659	1.117	-1.823
05	-0.839	0.778	-0.043	-0.839
06	1.154	-1.434	-1.057	-1.417
07	-1.451	1.188	-1.322	-1.523
08	-1.662	1.102	-0.82	-1.023
09	0.643	-0.307	-0.324	-0.449
10	-0.716	0.065	-1.249	0.769
11	-2.334	-3.435	1.343	-3.211
12	-2.948	-3.317	1.352	-3.116
13	1.236	-1.105	-2.468	-1.957
14	-2.568	1.212	-0.708	-2.68
15	1.349	-3.211	-2.805	-3.116
16	-2.154	-3.606	1.344	-3.767
17	-0.677	1.062	-1.326	-1.096
18	-0.147	-2.822	0.428	0.433
19	-0.457	0.947	-0.489	-1.733
20	-0.769	1.095	-2.226	-0.822
21	-0.088	0.597	-0.919	-0.142

Standard thresholds

P-value	Threshold
0.001	1.83996
0.0005	3.06036
0.0001	5.65241