MotifREST.H12CORE.0.P.B
Gene (human)REST
(GeneCards)
Gene synonyms (human)NRSF, XBR
Gene (mouse)Rest
Gene synonyms (mouse)Nrsf
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length22
ConsensusbbYRSnMCShhGGACAGMdSMh
GC content60.88%
Information content (bits; total / per base)18.577 / 0.844
Data sourcesChIP-Seq
Aligned words717

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 63 (418) 0.975 0.993 0.966 0.989 0.971 0.993 10.266 12.079 662.495 1089.244
Mouse 25 (165) 0.98 0.992 0.967 0.984 0.976 0.99 10.071 10.815 597.208 810.469

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.238 9.02 0.136 0.056
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMultiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamilyUnclassified {2.3.4.0} (TFClass)
TFClass IDTFClass: 2.3.4.0.27
HGNCHGNC:9966
MGIMGI:104897
EntrezGene (human)GeneID:5978
(SSTAR profile)
EntrezGene (mouse)GeneID:19712
(SSTAR profile)
UniProt ID (human)REST_HUMAN
UniProt ID (mouse)REST_MOUSE
UniProt AC (human)Q13127
(TFClass)
UniProt AC (mouse)Q8VIG1
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 63 human, 25 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01111.0145.0177.0284.0
0253.0207.078.0379.0
0361.0499.053.0104.0
04508.060.0109.040.0
0562.089.0534.032.0
0682.0395.0158.082.0
07562.054.050.051.0
0831.0595.045.046.0
0946.0541.090.040.0
10358.0122.0107.0130.0
1194.0178.063.0382.0
1214.09.0683.011.0
1310.014.0680.013.0
14635.040.012.030.0
157.0626.067.017.0
16699.05.08.05.0
176.05.0703.03.0
1889.0533.030.065.0
19185.010.0293.0229.0
2094.0452.0137.034.0
2174.0560.018.065.0
22180.0286.083.0168.0
PFM
ACGT
010.1550.2020.2470.396
020.0740.2890.1090.529
030.0850.6960.0740.145
040.7090.0840.1520.056
050.0860.1240.7450.045
060.1140.5510.220.114
070.7840.0750.070.071
080.0430.830.0630.064
090.0640.7550.1260.056
100.4990.170.1490.181
110.1310.2480.0880.533
120.020.0130.9530.015
130.0140.020.9480.018
140.8860.0560.0170.042
150.010.8730.0930.024
160.9750.0070.0110.007
170.0080.0070.980.004
180.1240.7430.0420.091
190.2580.0140.4090.319
200.1310.630.1910.047
210.1030.7810.0250.091
220.2510.3990.1160.234
PWM
ACGT
01-0.474-0.21-0.0130.457
02-1.1970.143-0.820.744
03-1.061.018-1.197-0.538
041.036-1.077-0.492-1.469
05-1.045-0.6911.086-1.682
06-0.7710.785-0.125-0.771
071.137-1.179-1.254-1.234
08-1.7121.193-1.355-1.334
09-1.3341.099-0.68-1.469
100.687-0.381-0.51-0.318
11-0.637-0.007-1.0290.752
12-2.448-2.8331.331-2.661
13-2.743-2.4481.327-2.514
141.258-1.469-2.585-1.743
15-3.0411.244-0.969-2.272
161.354-3.304-2.932-3.304
17-3.164-3.3041.36-3.662
18-0.6911.084-1.743-0.999
190.031-2.7430.4880.243
20-0.6370.919-0.266-1.624
21-0.8721.133-2.22-0.999
220.0040.464-0.759-0.064
Standard thresholds
P-value Threshold
0.001 1.95051
0.0005 3.15416
0.0001 5.71341