MotifRARG.H12INVITRO.0.P.B
Gene (human)RARG
(GeneCards)
Gene synonyms (human)NR1B3
Gene (mouse)Rarg
Gene synonyms (mouse)Nr1b3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length18
ConsensusbhvAGGTCAvnvhRvYYb
GC content58.41%
Information content (bits; total / per base)12.019 / 0.668
Data sourcesChIP-Seq
Aligned words920

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (21) 0.749 0.895 0.677 0.843 0.702 0.902 2.841 4.419 61.409 128.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.786 0.729 0.681 0.654 0.601 0.598
best 0.975 0.959 0.969 0.948 0.953 0.929
Methyl HT-SELEX, 2 experiments median 0.939 0.903 0.917 0.876 0.879 0.838
best 0.961 0.934 0.951 0.919 0.93 0.895
Non-Methyl HT-SELEX, 8 experiments median 0.731 0.681 0.636 0.616 0.573 0.572
best 0.975 0.959 0.969 0.948 0.953 0.929

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.88 0.026 0.911 0.458
batch 2 0.532 0.077 0.297 0.138
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyRAR (NR1B) {2.1.2.1} (TFClass)
TFClass IDTFClass: 2.1.2.1.3
HGNCHGNC:9866
MGIMGI:97858
EntrezGene (human)GeneID:5916
(SSTAR profile)
EntrezGene (mouse)GeneID:19411
(SSTAR profile)
UniProt ID (human)RARG_HUMAN
UniProt ID (mouse)RARG_MOUSE
UniProt AC (human)P13631
(TFClass)
UniProt AC (mouse)P18911
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 0 mouse
HT-SELEX 8
Methyl-HT-SELEX 2
PCM
ACGT
01111.0355.0219.0235.0
02169.0429.0152.0170.0
03251.0383.0155.0131.0
04700.011.0200.09.0
055.01.0816.098.0
0617.013.0843.047.0
0722.04.0105.0789.0
080.0853.059.08.0
09884.011.015.010.0
10123.0332.0352.0113.0
11232.0285.0289.0114.0
12178.0290.0324.0128.0
13176.0158.062.0524.0
14139.089.0640.052.0
15363.0266.0149.0142.0
1666.0650.071.0133.0
17101.0606.034.0179.0
1894.0343.0109.0374.0
PFM
ACGT
010.1210.3860.2380.255
020.1840.4660.1650.185
030.2730.4160.1680.142
040.7610.0120.2170.01
050.0050.0010.8870.107
060.0180.0140.9160.051
070.0240.0040.1140.858
080.00.9270.0640.009
090.9610.0120.0160.011
100.1340.3610.3830.123
110.2520.310.3140.124
120.1930.3150.3520.139
130.1910.1720.0670.57
140.1510.0970.6960.057
150.3950.2890.1620.154
160.0720.7070.0770.145
170.110.6590.0370.195
180.1020.3730.1180.407
PWM
ACGT
01-0.7210.431-0.0490.021
02-0.3060.62-0.41-0.3
030.0870.507-0.391-0.557
041.108-2.903-0.139-3.075
05-3.542-4.451.261-0.843
06-2.517-2.7571.294-1.56
07-2.28-3.704-0.7751.227
08-4.9111.305-1.339-3.173
091.341-2.903-2.63-2.985
10-0.620.3650.423-0.703
110.0090.2130.227-0.694
12-0.2540.230.341-0.58
13-0.265-0.372-1.2910.819
14-0.499-0.9381.019-1.462
150.4540.144-0.43-0.478
16-1.231.034-1.159-0.542
17-0.8140.964-1.87-0.249
18-0.8840.397-0.7390.483
Standard thresholds
P-value Threshold
0.001 4.22096
0.0005 5.18011
0.0001 7.15276