MotifPRRX2.H12INVIVO.1.S.D
Gene (human)PRRX2
(GeneCards)
Gene synonyms (human)PMX2, PRX2
Gene (mouse)Prrx2
Gene synonyms (mouse)Prx2, S8
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length16
ConsensusnbnbTAATTARhYdRn
GC content27.09%
Information content (bits; total / per base)14.974 / 0.936
Data sourcesHT-SELEX
Aligned words632

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.927 0.885 0.87 0.836 0.743 0.737
best 0.994 0.99 0.992 0.987 0.984 0.977
Methyl HT-SELEX, 2 experiments median 0.956 0.926 0.926 0.899 0.881 0.859
best 0.994 0.99 0.992 0.987 0.984 0.977
Non-Methyl HT-SELEX, 6 experiments median 0.927 0.885 0.834 0.816 0.679 0.699
best 0.969 0.945 0.954 0.927 0.875 0.851

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.878 0.79 0.835 0.606
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyPRRX {3.1.3.21} (TFClass)
TFClass IDTFClass: 3.1.3.21.2
HGNCHGNC:21338
MGIMGI:98218
EntrezGene (human)GeneID:51450
(SSTAR profile)
EntrezGene (mouse)GeneID:20204
(SSTAR profile)
UniProt ID (human)PRRX2_HUMAN
UniProt ID (mouse)PRRX2_MOUSE
UniProt AC (human)Q99811
(TFClass)
UniProt AC (mouse)Q06348
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
01116.75163.75162.75188.75
0283.0259.0131.0159.0
03174.0137.0231.090.0
0444.0322.094.0172.0
050.02.00.0630.0
06632.00.00.00.0
07632.00.00.00.0
080.00.00.0632.0
090.00.00.0632.0
10589.00.042.01.0
11348.016.0267.01.0
12265.062.048.0257.0
1318.083.048.0483.0
14130.085.0111.0306.0
15412.564.5108.546.5
16185.25119.25182.25145.25
PFM
ACGT
010.1850.2590.2580.299
020.1310.410.2070.252
030.2750.2170.3660.142
040.070.5090.1490.272
050.00.0030.00.997
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.00.01.0
100.9320.00.0660.002
110.5510.0250.4220.002
120.4190.0980.0760.407
130.0280.1310.0760.764
140.2060.1340.1760.484
150.6530.1020.1720.074
160.2930.1890.2880.23
PWM
ACGT
01-0.2990.0350.0290.176
02-0.6350.49-0.1850.006
030.096-0.1410.377-0.555
04-1.2530.707-0.5120.084
05-4.595-3.788-4.5951.376
061.379-4.595-4.595-4.595
071.379-4.595-4.595-4.595
08-4.595-4.595-4.5951.379
09-4.595-4.595-4.5951.379
101.308-4.595-1.297-4.113
110.784-2.2040.521-4.113
120.513-0.92-1.1690.483
13-2.097-0.635-1.1691.111
14-0.193-0.611-0.3490.656
150.953-0.881-0.371-1.199
160.158-0.2780.141-0.083
Standard thresholds
P-value Threshold
0.001 2.21976
0.0005 3.55091
0.0001 6.54461