| Motif | PRRX2.H12INVIVO.0.SM.D |
| Gene (human) | PRRX2 (GeneCards) |
| Gene synonyms (human) | PMX2, PRX2 |
| Gene (mouse) | Prrx2 |
| Gene synonyms (mouse) | Prx2, S8 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | PRRX2.H12INVIVO.0.SM.D |
| Gene (human) | PRRX2 (GeneCards) |
| Gene synonyms (human) | PMX2, PRX2 |
| Gene (mouse) | Prrx2 |
| Gene synonyms (mouse) | Prx2, S8 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 10 |
| Consensus | nvbTAATYRn |
| GC content | 32.22% |
| Information content (bits; total / per base) | 9.771 / 0.977 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9196 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.942 | 0.907 | 0.897 | 0.859 | 0.784 | 0.768 |
| best | 0.998 | 0.996 | 0.995 | 0.993 | 0.987 | 0.982 | |
| Methyl HT-SELEX, 2 experiments | median | 0.962 | 0.941 | 0.941 | 0.917 | 0.902 | 0.88 |
| best | 0.998 | 0.996 | 0.995 | 0.993 | 0.987 | 0.982 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.941 | 0.906 | 0.868 | 0.838 | 0.719 | 0.726 |
| best | 0.991 | 0.986 | 0.985 | 0.976 | 0.975 | 0.963 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.833 | 0.601 | 0.794 | 0.604 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | PRRX {3.1.3.21} (TFClass) |
| TFClass ID | TFClass: 3.1.3.21.2 |
| HGNC | HGNC:21338 |
| MGI | MGI:98218 |
| EntrezGene (human) | GeneID:51450 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20204 (SSTAR profile) |
| UniProt ID (human) | PRRX2_HUMAN |
| UniProt ID (mouse) | PRRX2_MOUSE |
| UniProt AC (human) | Q99811 (TFClass) |
| UniProt AC (mouse) | Q06348 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | PRRX2.H12INVIVO.0.SM.D.pcm |
| PWM | PRRX2.H12INVIVO.0.SM.D.pwm |
| PFM | PRRX2.H12INVIVO.0.SM.D.pfm |
| Alignment | PRRX2.H12INVIVO.0.SM.D.words.tsv |
| Threshold to P-value map | PRRX2.H12INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | PRRX2.H12INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | PRRX2.H12INVIVO.0.SM.D_meme_format.meme |
| Transfac format | PRRX2.H12INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1877.0 | 3232.0 | 2152.0 | 1935.0 |
| 02 | 1834.0 | 2763.0 | 3964.0 | 635.0 |
| 03 | 790.0 | 3834.0 | 1413.0 | 3159.0 |
| 04 | 0.0 | 8.0 | 0.0 | 9188.0 |
| 05 | 9196.0 | 0.0 | 0.0 | 0.0 |
| 06 | 9196.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 1.0 | 0.0 | 9195.0 |
| 08 | 138.0 | 1602.0 | 854.0 | 6602.0 |
| 09 | 4417.75 | 690.75 | 3582.75 | 504.75 |
| 10 | 2048.5 | 2723.5 | 2809.5 | 1614.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.204 | 0.351 | 0.234 | 0.21 |
| 02 | 0.199 | 0.3 | 0.431 | 0.069 |
| 03 | 0.086 | 0.417 | 0.154 | 0.344 |
| 04 | 0.0 | 0.001 | 0.0 | 0.999 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1.0 |
| 08 | 0.015 | 0.174 | 0.093 | 0.718 |
| 09 | 0.48 | 0.075 | 0.39 | 0.055 |
| 10 | 0.223 | 0.296 | 0.306 | 0.176 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.203 | 0.34 | -0.066 | -0.172 |
| 02 | -0.226 | 0.184 | 0.544 | -1.284 |
| 03 | -1.066 | 0.511 | -0.486 | 0.318 |
| 04 | -6.916 | -5.411 | -6.916 | 1.385 |
| 05 | 1.386 | -6.916 | -6.916 | -6.916 |
| 06 | 1.386 | -6.916 | -6.916 | -6.916 |
| 07 | -6.916 | -6.553 | -6.916 | 1.385 |
| 08 | -2.798 | -0.361 | -0.989 | 1.054 |
| 09 | 0.653 | -1.2 | 0.443 | -1.513 |
| 10 | -0.115 | 0.169 | 0.2 | -0.353 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.326535 |
| 0.0005 | 6.205115 |
| 0.0001 | 7.63783 |