Motif | PRRX2.H12CORE.1.S.B |
Gene (human) | PRRX2 (GeneCards) |
Gene synonyms (human) | PMX2, PRX2 |
Gene (mouse) | Prrx2 |
Gene synonyms (mouse) | Prx2, S8 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | PRRX2.H12CORE.1.S.B |
Gene (human) | PRRX2 (GeneCards) |
Gene synonyms (human) | PMX2, PRX2 |
Gene (mouse) | Prrx2 |
Gene synonyms (mouse) | Prx2, S8 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 16 |
Consensus | nbnbTAATTARhYdRn |
GC content | 27.09% |
Information content (bits; total / per base) | 14.974 / 0.936 |
Data sources | HT-SELEX |
Aligned words | 632 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.927 | 0.885 | 0.87 | 0.836 | 0.743 | 0.737 |
best | 0.994 | 0.99 | 0.992 | 0.987 | 0.984 | 0.977 | |
Methyl HT-SELEX, 2 experiments | median | 0.956 | 0.926 | 0.926 | 0.899 | 0.881 | 0.859 |
best | 0.994 | 0.99 | 0.992 | 0.987 | 0.984 | 0.977 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.927 | 0.885 | 0.834 | 0.816 | 0.679 | 0.699 |
best | 0.969 | 0.945 | 0.954 | 0.927 | 0.875 | 0.851 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.878 | 0.79 | 0.835 | 0.606 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | PRRX {3.1.3.21} (TFClass) |
TFClass ID | TFClass: 3.1.3.21.2 |
HGNC | HGNC:21338 |
MGI | MGI:98218 |
EntrezGene (human) | GeneID:51450 (SSTAR profile) |
EntrezGene (mouse) | GeneID:20204 (SSTAR profile) |
UniProt ID (human) | PRRX2_HUMAN |
UniProt ID (mouse) | PRRX2_MOUSE |
UniProt AC (human) | Q99811 (TFClass) |
UniProt AC (mouse) | Q06348 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | PRRX2.H12CORE.1.S.B.pcm |
PWM | PRRX2.H12CORE.1.S.B.pwm |
PFM | PRRX2.H12CORE.1.S.B.pfm |
Alignment | PRRX2.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | PRRX2.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | PRRX2.H12CORE.1.S.B_jaspar_format.txt |
MEME format | PRRX2.H12CORE.1.S.B_meme_format.meme |
Transfac format | PRRX2.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 116.75 | 163.75 | 162.75 | 188.75 |
02 | 83.0 | 259.0 | 131.0 | 159.0 |
03 | 174.0 | 137.0 | 231.0 | 90.0 |
04 | 44.0 | 322.0 | 94.0 | 172.0 |
05 | 0.0 | 2.0 | 0.0 | 630.0 |
06 | 632.0 | 0.0 | 0.0 | 0.0 |
07 | 632.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.0 | 632.0 |
09 | 0.0 | 0.0 | 0.0 | 632.0 |
10 | 589.0 | 0.0 | 42.0 | 1.0 |
11 | 348.0 | 16.0 | 267.0 | 1.0 |
12 | 265.0 | 62.0 | 48.0 | 257.0 |
13 | 18.0 | 83.0 | 48.0 | 483.0 |
14 | 130.0 | 85.0 | 111.0 | 306.0 |
15 | 412.5 | 64.5 | 108.5 | 46.5 |
16 | 185.25 | 119.25 | 182.25 | 145.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.185 | 0.259 | 0.258 | 0.299 |
02 | 0.131 | 0.41 | 0.207 | 0.252 |
03 | 0.275 | 0.217 | 0.366 | 0.142 |
04 | 0.07 | 0.509 | 0.149 | 0.272 |
05 | 0.0 | 0.003 | 0.0 | 0.997 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.0 | 1.0 |
09 | 0.0 | 0.0 | 0.0 | 1.0 |
10 | 0.932 | 0.0 | 0.066 | 0.002 |
11 | 0.551 | 0.025 | 0.422 | 0.002 |
12 | 0.419 | 0.098 | 0.076 | 0.407 |
13 | 0.028 | 0.131 | 0.076 | 0.764 |
14 | 0.206 | 0.134 | 0.176 | 0.484 |
15 | 0.653 | 0.102 | 0.172 | 0.074 |
16 | 0.293 | 0.189 | 0.288 | 0.23 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.299 | 0.035 | 0.029 | 0.176 |
02 | -0.635 | 0.49 | -0.185 | 0.006 |
03 | 0.096 | -0.141 | 0.377 | -0.555 |
04 | -1.253 | 0.707 | -0.512 | 0.084 |
05 | -4.595 | -3.788 | -4.595 | 1.376 |
06 | 1.379 | -4.595 | -4.595 | -4.595 |
07 | 1.379 | -4.595 | -4.595 | -4.595 |
08 | -4.595 | -4.595 | -4.595 | 1.379 |
09 | -4.595 | -4.595 | -4.595 | 1.379 |
10 | 1.308 | -4.595 | -1.297 | -4.113 |
11 | 0.784 | -2.204 | 0.521 | -4.113 |
12 | 0.513 | -0.92 | -1.169 | 0.483 |
13 | -2.097 | -0.635 | -1.169 | 1.111 |
14 | -0.193 | -0.611 | -0.349 | 0.656 |
15 | 0.953 | -0.881 | -0.371 | -1.199 |
16 | 0.158 | -0.278 | 0.141 | -0.083 |
P-value | Threshold |
---|---|
0.001 | 2.21976 |
0.0005 | 3.55091 |
0.0001 | 6.54461 |