MotifPRRX2.H12CORE.0.SM.B
Gene (human)PRRX2
(GeneCards)
Gene synonyms (human)PMX2, PRX2
Gene (mouse)Prrx2
Gene synonyms (mouse)Prx2, S8
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnvbTAATYRn
GC content32.22%
Information content (bits; total / per base)9.771 / 0.977
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9196

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.942 0.907 0.897 0.859 0.784 0.768
best 0.998 0.996 0.995 0.993 0.987 0.982
Methyl HT-SELEX, 2 experiments median 0.962 0.941 0.941 0.917 0.902 0.88
best 0.998 0.996 0.995 0.993 0.987 0.982
Non-Methyl HT-SELEX, 6 experiments median 0.941 0.906 0.868 0.838 0.719 0.726
best 0.991 0.986 0.985 0.976 0.975 0.963

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.833 0.601 0.794 0.604
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyPRRX {3.1.3.21} (TFClass)
TFClass IDTFClass: 3.1.3.21.2
HGNCHGNC:21338
MGIMGI:98218
EntrezGene (human)GeneID:51450
(SSTAR profile)
EntrezGene (mouse)GeneID:20204
(SSTAR profile)
UniProt ID (human)PRRX2_HUMAN
UniProt ID (mouse)PRRX2_MOUSE
UniProt AC (human)Q99811
(TFClass)
UniProt AC (mouse)Q06348
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
011877.03232.02152.01935.0
021834.02763.03964.0635.0
03790.03834.01413.03159.0
040.08.00.09188.0
059196.00.00.00.0
069196.00.00.00.0
070.01.00.09195.0
08138.01602.0854.06602.0
094417.75690.753582.75504.75
102048.52723.52809.51614.5
PFM
ACGT
010.2040.3510.2340.21
020.1990.30.4310.069
030.0860.4170.1540.344
040.00.0010.00.999
051.00.00.00.0
061.00.00.00.0
070.00.00.01.0
080.0150.1740.0930.718
090.480.0750.390.055
100.2230.2960.3060.176
PWM
ACGT
01-0.2030.34-0.066-0.172
02-0.2260.1840.544-1.284
03-1.0660.511-0.4860.318
04-6.916-5.411-6.9161.385
051.386-6.916-6.916-6.916
061.386-6.916-6.916-6.916
07-6.916-6.553-6.9161.385
08-2.798-0.361-0.9891.054
090.653-1.20.443-1.513
10-0.1150.1690.2-0.353
Standard thresholds
P-value Threshold
0.001 5.326535
0.0005 6.205115
0.0001 7.63783