PRRX1.H12RSNP.1.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PRRX1.H12RSNP.1.S.D
Gene (human)	PRRX1 (GeneCards)
Gene synonyms (human)	PMX1
Gene (mouse)	Prrx1
Gene synonyms (mouse)	Pmx, Pmx1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	17
Consensus	nvYTAATTARhYhAdWd
GC content	27.04%
Information content (bits; total / per base)	15.863 / 0.933
Data sources	HT-SELEX
Aligned words	5328

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.965	0.947	0.893	0.876	0.744	0.756
Non-Methyl HT-SELEX, 4 experiments	best	0.995	0.992	0.989	0.983	0.974	0.964

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	Paired-related HD {3.1.3} (TFClass)
TF subfamily	PRRX {3.1.3.21} (TFClass)
TFClass ID	TFClass: 3.1.3.21.1
HGNC	HGNC:9142
MGI	MGI:97712
EntrezGene (human)	GeneID:5396 (SSTAR profile)
EntrezGene (mouse)	GeneID:18933 (SSTAR profile)
UniProt ID (human)	PRRX1_HUMAN
UniProt ID (mouse)	PRRX1_MOUSE
UniProt AC (human)	P54821 (TFClass)
UniProt AC (mouse)	P63013 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	PRRX1.H12RSNP.1.S.D.pcm
PWM	PRRX1.H12RSNP.1.S.D.pwm
PFM	PRRX1.H12RSNP.1.S.D.pfm
Alignment	PRRX1.H12RSNP.1.S.D.words.tsv
Threshold to P-value map	PRRX1.H12RSNP.1.S.D.thr
Motif in other formats
JASPAR format	PRRX1.H12RSNP.1.S.D_jaspar_format.txt
MEME format	PRRX1.H12RSNP.1.S.D_meme_format.meme
Transfac format	PRRX1.H12RSNP.1.S.D_transfac_format.txt
Homer format	PRRX1.H12RSNP.1.S.D_homer_format_0.001.txt PRRX1.H12RSNP.1.S.D_homer_format_0.0005.txt PRRX1.H12RSNP.1.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1008.25	1964.25	1465.25	890.25
02	1240.75	1682.75	1944.75	459.75
03	109.0	3087.0	881.0	1251.0
04	0.0	77.0	0.0	5251.0
05	5328.0	0.0	0.0	0.0
06	5328.0	0.0	0.0	0.0
07	0.0	0.0	0.0	5328.0
08	0.0	0.0	0.0	5328.0
09	4022.0	0.0	1306.0	0.0
10	1228.0	224.0	3875.0	1.0
11	2012.0	1181.0	583.0	1552.0
12	417.0	761.0	448.0	3702.0
13	2254.0	461.0	363.0	2250.0
14	4313.0	192.0	145.0	678.0
15	1638.0	380.0	760.0	2550.0
16	1055.25	634.25	468.25	3170.25
17	2034.5	556.5	1048.5	1688.5

PFM

	A	C	G	T
01	0.189	0.369	0.275	0.167
02	0.233	0.316	0.365	0.086
03	0.02	0.579	0.165	0.235
04	0.0	0.014	0.0	0.986
05	1.0	0.0	0.0	0.0
06	1.0	0.0	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.755	0.0	0.245	0.0
10	0.23	0.042	0.727	0.0
11	0.378	0.222	0.109	0.291
12	0.078	0.143	0.084	0.695
13	0.423	0.087	0.068	0.422
14	0.809	0.036	0.027	0.127
15	0.307	0.071	0.143	0.479
16	0.198	0.119	0.088	0.595
17	0.382	0.104	0.197	0.317

PWM

	A	C	G	T
01	-0.278	0.388	0.095	-0.402
02	-0.071	0.233	0.378	-1.061
03	-2.485	0.84	-0.413	-0.063
04	-6.433	-2.825	-6.433	1.371
05	1.385	-6.433	-6.433	-6.433
06	1.385	-6.433	-6.433	-6.433
07	-6.433	-6.433	-6.433	1.385
08	-6.433	-6.433	-6.433	1.385
09	1.104	-6.433	-0.02	-6.433
10	-0.081	-1.775	1.067	-6.05
11	0.412	-0.12	-0.824	0.153
12	-1.158	-0.559	-1.086	1.021
13	0.525	-1.058	-1.296	0.524
14	1.174	-1.927	-2.205	-0.674
15	0.206	-1.25	-0.56	0.649
16	-0.232	-0.74	-1.042	0.866
17	0.423	-0.871	-0.239	0.237

Standard thresholds

P-value	Threshold
0.001	0.31816
0.0005	2.04246
0.0001	6.01076