PROX1.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PROX1.H12INVIVO.0.SM.D
Gene (human)	PROX1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Prox1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	13
Consensus	nnvYGTCTTRvvn
GC content	50.16%
Information content (bits; total / per base)	10.681 / 0.822
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2121

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.783	0.759	0.737	0.717	0.692	0.677
Overall, 4 experiments	best	0.955	0.927	0.934	0.899	0.892	0.854
Methyl HT-SELEX, 1 experiments	median	0.955	0.927	0.934	0.899	0.892	0.854
Methyl HT-SELEX, 1 experiments	best	0.955	0.927	0.934	0.899	0.892	0.854
Non-Methyl HT-SELEX, 3 experiments	median	0.614	0.595	0.558	0.554	0.522	0.53
Non-Methyl HT-SELEX, 3 experiments	best	0.951	0.922	0.915	0.88	0.861	0.823

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HD-PROS {3.1.7} (TFClass)
TF subfamily	{3.1.7.0} (TFClass)
TFClass ID	TFClass: 3.1.7.0.1
HGNC	HGNC:9459
MGI	MGI:97772
EntrezGene (human)	GeneID:5629 (SSTAR profile)
EntrezGene (mouse)	GeneID:19130 (SSTAR profile)
UniProt ID (human)	PROX1_HUMAN
UniProt ID (mouse)	PROX1_MOUSE
UniProt AC (human)	Q92786 (TFClass)
UniProt AC (mouse)	P48437 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	PROX1.H12INVIVO.0.SM.D.pcm
PWM	PROX1.H12INVIVO.0.SM.D.pwm
PFM	PROX1.H12INVIVO.0.SM.D.pfm
Alignment	PROX1.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	PROX1.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	PROX1.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	PROX1.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	PROX1.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	PROX1.H12INVIVO.0.SM.D_homer_format_0.001.txt PROX1.H12INVIVO.0.SM.D_homer_format_0.0005.txt PROX1.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	629.75	431.75	542.75	516.75
02	328.0	493.0	745.0	555.0
03	876.0	260.0	740.0	245.0
04	101.0	1584.0	75.0	361.0
05	331.0	0.0	1641.0	149.0
06	0.0	139.0	0.0	1982.0
07	0.0	2121.0	0.0	0.0
08	0.0	0.0	0.0	2121.0
09	0.0	3.0	0.0	2118.0
10	704.0	231.0	1175.0	11.0
11	778.0	569.0	565.0	209.0
12	470.25	532.25	836.25	282.25
13	492.75	426.75	718.75	482.75

PFM

	A	C	G	T
01	0.297	0.204	0.256	0.244
02	0.155	0.232	0.351	0.262
03	0.413	0.123	0.349	0.116
04	0.048	0.747	0.035	0.17
05	0.156	0.0	0.774	0.07
06	0.0	0.066	0.0	0.934
07	0.0	1.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.001	0.0	0.999
10	0.332	0.109	0.554	0.005
11	0.367	0.268	0.266	0.099
12	0.222	0.251	0.394	0.133
13	0.232	0.201	0.339	0.228

PWM

	A	C	G	T
01	0.171	-0.205	0.023	-0.026
02	-0.478	-0.073	0.339	0.045
03	0.501	-0.709	0.332	-0.768
04	-1.643	1.092	-1.934	-0.383
05	-0.469	-5.627	1.127	-1.26
06	-5.627	-1.329	-5.627	1.316
07	-5.627	1.384	-5.627	-5.627
08	-5.627	-5.627	-5.627	1.384
09	-5.627	-4.685	-5.627	1.382
10	0.283	-0.826	0.794	-3.719
11	0.382	0.07	0.063	-0.925
12	-0.12	0.004	0.454	-0.627
13	-0.073	-0.216	0.303	-0.093

Standard thresholds

P-value	Threshold
0.001	4.73321
0.0005	5.817515
0.0001	7.61691