MotifPROX1.H12INVIVO.0.SM.D
Gene (human)PROX1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Prox1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length13
ConsensusnnvYGTCTTRvvn
GC content50.16%
Information content (bits; total / per base)10.681 / 0.822
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2121

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.783 0.759 0.737 0.717 0.692 0.677
best 0.955 0.927 0.934 0.899 0.892 0.854
Methyl HT-SELEX, 1 experiments median 0.955 0.927 0.934 0.899 0.892 0.854
best 0.955 0.927 0.934 0.899 0.892 0.854
Non-Methyl HT-SELEX, 3 experiments median 0.614 0.595 0.558 0.554 0.522 0.53
best 0.951 0.922 0.915 0.88 0.861 0.823
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-PROS {3.1.7} (TFClass)
TF subfamily {3.1.7.0} (TFClass)
TFClass IDTFClass: 3.1.7.0.1
HGNCHGNC:9459
MGIMGI:97772
EntrezGene (human)GeneID:5629
(SSTAR profile)
EntrezGene (mouse)GeneID:19130
(SSTAR profile)
UniProt ID (human)PROX1_HUMAN
UniProt ID (mouse)PROX1_MOUSE
UniProt AC (human)Q92786
(TFClass)
UniProt AC (mouse)P48437
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01629.75431.75542.75516.75
02328.0493.0745.0555.0
03876.0260.0740.0245.0
04101.01584.075.0361.0
05331.00.01641.0149.0
060.0139.00.01982.0
070.02121.00.00.0
080.00.00.02121.0
090.03.00.02118.0
10704.0231.01175.011.0
11778.0569.0565.0209.0
12470.25532.25836.25282.25
13492.75426.75718.75482.75
PFM
ACGT
010.2970.2040.2560.244
020.1550.2320.3510.262
030.4130.1230.3490.116
040.0480.7470.0350.17
050.1560.00.7740.07
060.00.0660.00.934
070.01.00.00.0
080.00.00.01.0
090.00.0010.00.999
100.3320.1090.5540.005
110.3670.2680.2660.099
120.2220.2510.3940.133
130.2320.2010.3390.228
PWM
ACGT
010.171-0.2050.023-0.026
02-0.478-0.0730.3390.045
030.501-0.7090.332-0.768
04-1.6431.092-1.934-0.383
05-0.469-5.6271.127-1.26
06-5.627-1.329-5.6271.316
07-5.6271.384-5.627-5.627
08-5.627-5.627-5.6271.384
09-5.627-4.685-5.6271.382
100.283-0.8260.794-3.719
110.3820.070.063-0.925
12-0.120.0040.454-0.627
13-0.073-0.2160.303-0.093
Standard thresholds
P-value Threshold
0.001 4.73321
0.0005 5.817515
0.0001 7.61691