Motif | PROP1.H12CORE.0.PSM.A |
Gene (human) | PROP1 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Prop1 |
Gene synonyms (mouse) | Prop-1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | PROP1.H12CORE.0.PSM.A |
Gene (human) | PROP1 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Prop1 |
Gene synonyms (mouse) | Prop-1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 16 |
Consensus | nvbTAATTRvRTTAvn |
GC content | 29.52% |
Information content (bits; total / per base) | 16.099 / 1.006 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9455 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 1 (7) | 0.925 | 0.934 | 0.853 | 0.88 | 0.897 | 0.91 | 3.592 | 3.669 | 367.824 | 415.959 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 10 experiments | median | 0.999 | 0.997 | 0.996 | 0.994 | 0.975 | 0.972 |
best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.999 | |
Methyl HT-SELEX, 3 experiments | median | 0.999 | 0.999 | 0.999 | 0.998 | 0.989 | 0.987 |
best | 1.0 | 0.999 | 0.999 | 0.999 | 0.998 | 0.996 | |
Non-Methyl HT-SELEX, 7 experiments | median | 0.998 | 0.996 | 0.993 | 0.99 | 0.865 | 0.883 |
best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.999 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.953 | 0.796 | 0.938 | 0.642 |
batch 2 | 0.866 | 0.626 | 0.839 | 0.655 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | Paired-related HD {3.1.3} (TFClass) |
TF subfamily | PROP {3.1.3.20} (TFClass) |
TFClass ID | TFClass: 3.1.3.20.1 |
HGNC | HGNC:9455 |
MGI | MGI:109330 |
EntrezGene (human) | GeneID:5626 (SSTAR profile) |
EntrezGene (mouse) | GeneID:19127 (SSTAR profile) |
UniProt ID (human) | PROP1_HUMAN |
UniProt ID (mouse) | PROP1_MOUSE |
UniProt AC (human) | O75360 (TFClass) |
UniProt AC (mouse) | P97458 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 1 mouse |
HT-SELEX | 7 |
Methyl-HT-SELEX | 3 |
PCM | PROP1.H12CORE.0.PSM.A.pcm |
PWM | PROP1.H12CORE.0.PSM.A.pwm |
PFM | PROP1.H12CORE.0.PSM.A.pfm |
Alignment | PROP1.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | PROP1.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | PROP1.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | PROP1.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | PROP1.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2120.25 | 2706.25 | 2649.25 | 1979.25 |
02 | 1934.0 | 2376.0 | 3820.0 | 1325.0 |
03 | 1051.0 | 3452.0 | 2361.0 | 2591.0 |
04 | 299.0 | 337.0 | 93.0 | 8726.0 |
05 | 9162.0 | 7.0 | 225.0 | 61.0 |
06 | 9453.0 | 0.0 | 2.0 | 0.0 |
07 | 8.0 | 47.0 | 21.0 | 9379.0 |
08 | 33.0 | 1770.0 | 336.0 | 7316.0 |
09 | 6252.0 | 18.0 | 2808.0 | 377.0 |
10 | 2503.0 | 2949.0 | 3901.0 | 102.0 |
11 | 6403.0 | 83.0 | 2803.0 | 166.0 |
12 | 4.0 | 7.0 | 8.0 | 9436.0 |
13 | 63.0 | 148.0 | 21.0 | 9223.0 |
14 | 8692.0 | 84.0 | 314.0 | 365.0 |
15 | 2843.5 | 1872.5 | 3539.5 | 1199.5 |
16 | 1413.0 | 3293.0 | 2602.0 | 2147.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.224 | 0.286 | 0.28 | 0.209 |
02 | 0.205 | 0.251 | 0.404 | 0.14 |
03 | 0.111 | 0.365 | 0.25 | 0.274 |
04 | 0.032 | 0.036 | 0.01 | 0.923 |
05 | 0.969 | 0.001 | 0.024 | 0.006 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.001 | 0.005 | 0.002 | 0.992 |
08 | 0.003 | 0.187 | 0.036 | 0.774 |
09 | 0.661 | 0.002 | 0.297 | 0.04 |
10 | 0.265 | 0.312 | 0.413 | 0.011 |
11 | 0.677 | 0.009 | 0.296 | 0.018 |
12 | 0.0 | 0.001 | 0.001 | 0.998 |
13 | 0.007 | 0.016 | 0.002 | 0.975 |
14 | 0.919 | 0.009 | 0.033 | 0.039 |
15 | 0.301 | 0.198 | 0.374 | 0.127 |
16 | 0.149 | 0.348 | 0.275 | 0.227 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.109 | 0.135 | 0.114 | -0.177 |
02 | -0.2 | 0.005 | 0.48 | -0.578 |
03 | -0.809 | 0.378 | -0.001 | 0.092 |
04 | -2.061 | -1.942 | -3.212 | 1.305 |
05 | 1.354 | -5.54 | -2.343 | -3.621 |
06 | 1.385 | -6.941 | -6.313 | -6.941 |
07 | -5.438 | -3.871 | -4.621 | 1.378 |
08 | -4.205 | -0.289 | -1.945 | 1.129 |
09 | 0.972 | -4.759 | 0.172 | -1.831 |
10 | 0.057 | 0.221 | 0.501 | -3.122 |
11 | 0.996 | -3.323 | 0.17 | -2.643 |
12 | -5.93 | -5.54 | -5.438 | 1.384 |
13 | -3.59 | -2.756 | -4.621 | 1.361 |
14 | 1.301 | -3.311 | -2.012 | -1.863 |
15 | 0.185 | -0.233 | 0.403 | -0.677 |
16 | -0.514 | 0.331 | 0.096 | -0.096 |
P-value | Threshold |
---|---|
0.001 | 1.11351 |
0.0005 | 2.65276 |
0.0001 | 5.79856 |