MotifPROP1.H12CORE.0.PSM.A
Gene (human)PROP1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Prop1
Gene synonyms (mouse)Prop-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusnvbTAATTRvRTTAvn
GC content29.52%
Information content (bits; total / per base)16.099 / 1.006
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9455

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.925 0.934 0.853 0.88 0.897 0.91 3.592 3.669 367.824 415.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.999 0.997 0.996 0.994 0.975 0.972
best 1.0 1.0 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 3 experiments median 0.999 0.999 0.999 0.998 0.989 0.987
best 1.0 0.999 0.999 0.999 0.998 0.996
Non-Methyl HT-SELEX, 7 experiments median 0.998 0.996 0.993 0.99 0.865 0.883
best 1.0 1.0 1.0 0.999 0.999 0.999

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.953 0.796 0.938 0.642
batch 2 0.866 0.626 0.839 0.655
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyPROP {3.1.3.20} (TFClass)
TFClass IDTFClass: 3.1.3.20.1
HGNCHGNC:9455
MGIMGI:109330
EntrezGene (human)GeneID:5626
(SSTAR profile)
EntrezGene (mouse)GeneID:19127
(SSTAR profile)
UniProt ID (human)PROP1_HUMAN
UniProt ID (mouse)PROP1_MOUSE
UniProt AC (human)O75360
(TFClass)
UniProt AC (mouse)P97458
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
012120.252706.252649.251979.25
021934.02376.03820.01325.0
031051.03452.02361.02591.0
04299.0337.093.08726.0
059162.07.0225.061.0
069453.00.02.00.0
078.047.021.09379.0
0833.01770.0336.07316.0
096252.018.02808.0377.0
102503.02949.03901.0102.0
116403.083.02803.0166.0
124.07.08.09436.0
1363.0148.021.09223.0
148692.084.0314.0365.0
152843.51872.53539.51199.5
161413.03293.02602.02147.0
PFM
ACGT
010.2240.2860.280.209
020.2050.2510.4040.14
030.1110.3650.250.274
040.0320.0360.010.923
050.9690.0010.0240.006
061.00.00.00.0
070.0010.0050.0020.992
080.0030.1870.0360.774
090.6610.0020.2970.04
100.2650.3120.4130.011
110.6770.0090.2960.018
120.00.0010.0010.998
130.0070.0160.0020.975
140.9190.0090.0330.039
150.3010.1980.3740.127
160.1490.3480.2750.227
PWM
ACGT
01-0.1090.1350.114-0.177
02-0.20.0050.48-0.578
03-0.8090.378-0.0010.092
04-2.061-1.942-3.2121.305
051.354-5.54-2.343-3.621
061.385-6.941-6.313-6.941
07-5.438-3.871-4.6211.378
08-4.205-0.289-1.9451.129
090.972-4.7590.172-1.831
100.0570.2210.501-3.122
110.996-3.3230.17-2.643
12-5.93-5.54-5.4381.384
13-3.59-2.756-4.6211.361
141.301-3.311-2.012-1.863
150.185-0.2330.403-0.677
16-0.5140.3310.096-0.096
Standard thresholds
P-value Threshold
0.001 1.11351
0.0005 2.65276
0.0001 5.79856