PRGR.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PRGR.H12RSNP.0.P.B
Gene (human)	PGR (GeneCards)
Gene synonyms (human)	NR3C3
Gene (mouse)	Pgr
Gene synonyms (mouse)	Nr3c3, Pr
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	RKnMCWYYbYSTbCY
GC content	48.2%
Information content (bits; total / per base)	10.598 / 0.707
Data sources	ChIP-Seq
Aligned words	1008

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	28 (158)	0.838	0.954	0.736	0.923	0.822	0.942	2.849	4.743	138.508	489.018
Mouse	8 (55)	0.832	0.932	0.749	0.881	0.842	0.924	3.167	4.04	161.523	418.585

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	10.331	7.06	0.277	0.187

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.3
HGNC	HGNC:8910
MGI	MGI:97567
EntrezGene (human)	GeneID:5241 (SSTAR profile)
EntrezGene (mouse)	GeneID:18667 (SSTAR profile)
UniProt ID (human)	PRGR_HUMAN
UniProt ID (mouse)	PRGR_MOUSE
UniProt AC (human)	P06401 (TFClass)
UniProt AC (mouse)	Q00175 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	28 human, 8 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	PRGR.H12RSNP.0.P.B.pcm
PWM	PRGR.H12RSNP.0.P.B.pwm
PFM	PRGR.H12RSNP.0.P.B.pfm
Alignment	PRGR.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	PRGR.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	PRGR.H12RSNP.0.P.B_jaspar_format.txt
MEME format	PRGR.H12RSNP.0.P.B_meme_format.meme
Transfac format	PRGR.H12RSNP.0.P.B_transfac_format.txt
Homer format	PRGR.H12RSNP.0.P.B_homer_format_0.001.txt PRGR.H12RSNP.0.P.B_homer_format_0.0005.txt PRGR.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	526.0	46.0	330.0	106.0
02	96.0	40.0	745.0	127.0
03	375.0	189.0	231.0	213.0
04	724.0	206.0	40.0	38.0
05	16.0	964.0	20.0	8.0
06	726.0	35.0	61.0	186.0
07	49.0	201.0	137.0	621.0
08	47.0	222.0	153.0	586.0
09	49.0	535.0	180.0	244.0
10	89.0	179.0	74.0	666.0
11	95.0	137.0	723.0	53.0
12	36.0	82.0	26.0	864.0
13	95.0	227.0	130.0	556.0
14	35.0	864.0	15.0	94.0
15	56.0	476.0	20.0	456.0

PFM

	A	C	G	T
01	0.522	0.046	0.327	0.105
02	0.095	0.04	0.739	0.126
03	0.372	0.188	0.229	0.211
04	0.718	0.204	0.04	0.038
05	0.016	0.956	0.02	0.008
06	0.72	0.035	0.061	0.185
07	0.049	0.199	0.136	0.616
08	0.047	0.22	0.152	0.581
09	0.049	0.531	0.179	0.242
10	0.088	0.178	0.073	0.661
11	0.094	0.136	0.717	0.053
12	0.036	0.081	0.026	0.857
13	0.094	0.225	0.129	0.552
14	0.035	0.857	0.015	0.093
15	0.056	0.472	0.02	0.452

PWM

	A	C	G	T
01	0.732	-1.671	0.268	-0.857
02	-0.954	-1.805	1.079	-0.679
03	0.395	-0.285	-0.086	-0.167
04	1.051	-0.2	-1.805	-1.854
05	-2.661	1.337	-2.458	-3.261
06	1.054	-1.933	-1.397	-0.301
07	-1.61	-0.224	-0.604	0.898
08	-1.65	-0.126	-0.495	0.84
09	-1.61	0.749	-0.334	-0.032
10	-1.028	-0.339	-1.209	0.968
11	-0.964	-0.604	1.05	-1.534
12	-1.906	-1.109	-2.214	1.227
13	-0.964	-0.104	-0.656	0.788
14	-1.933	1.227	-2.719	-0.975
15	-1.481	0.633	-2.458	0.59

Standard thresholds

P-value	Threshold
0.001	4.57576
0.0005	5.40461
0.0001	7.13501