PRGR.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PRGR.H12INVITRO.0.P.D
Gene (human)	PGR (GeneCards)
Gene synonyms (human)	NR3C3
Gene (mouse)	Pgr
Gene synonyms (mouse)	Nr3c3, Pr
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	15
Consensus	RGdACWbTnTGThCY
GC content	42.8%
Information content (bits; total / per base)	13.976 / 0.932
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	28 (158)	0.856	0.971	0.765	0.95	0.831	0.97	2.998	5.364	178.313	563.481
Mouse	8 (55)	0.861	0.952	0.792	0.916	0.872	0.945	3.486	4.398	199.081	489.201

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	9.799	6.725	0.275	0.182

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Steroid hormone receptors {2.1.1} (TFClass)
TF subfamily	GR-like (NR3C) {2.1.1.1} (TFClass)
TFClass ID	TFClass: 2.1.1.1.3
HGNC	HGNC:8910
MGI	MGI:97567
EntrezGene (human)	GeneID:5241 (SSTAR profile)
EntrezGene (mouse)	GeneID:18667 (SSTAR profile)
UniProt ID (human)	PRGR_HUMAN
UniProt ID (mouse)	PRGR_MOUSE
UniProt AC (human)	P06401 (TFClass)
UniProt AC (mouse)	Q00175 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	28 human, 8 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	PRGR.H12INVITRO.0.P.D.pcm
PWM	PRGR.H12INVITRO.0.P.D.pwm
PFM	PRGR.H12INVITRO.0.P.D.pfm
Alignment	PRGR.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	PRGR.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	PRGR.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	PRGR.H12INVITRO.0.P.D_meme_format.meme
Transfac format	PRGR.H12INVITRO.0.P.D_transfac_format.txt
Homer format	PRGR.H12INVITRO.0.P.D_homer_format_0.001.txt PRGR.H12INVITRO.0.P.D_homer_format_0.0005.txt PRGR.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	508.0	10.0	367.0	115.0
02	83.0	7.0	851.0	59.0
03	547.0	96.0	177.0	180.0
04	960.0	8.0	7.0	25.0
05	0.0	969.0	11.0	20.0
06	747.0	19.0	75.0	159.0
07	96.0	188.0	241.0	475.0
08	0.0	282.0	0.0	718.0
09	262.0	315.0	168.0	255.0
10	95.0	74.0	20.0	811.0
11	28.0	25.0	941.0	6.0
12	22.0	10.0	11.0	957.0
13	229.0	188.0	111.0	472.0
14	60.0	841.0	7.0	92.0
15	119.0	377.0	24.0	480.0

PFM

	A	C	G	T
01	0.508	0.01	0.367	0.115
02	0.083	0.007	0.851	0.059
03	0.547	0.096	0.177	0.18
04	0.96	0.008	0.007	0.025
05	0.0	0.969	0.011	0.02
06	0.747	0.019	0.075	0.159
07	0.096	0.188	0.241	0.475
08	0.0	0.282	0.0	0.718
09	0.262	0.315	0.168	0.255
10	0.095	0.074	0.02	0.811
11	0.028	0.025	0.941	0.006
12	0.022	0.01	0.011	0.957
13	0.229	0.188	0.111	0.472
14	0.06	0.841	0.007	0.092
15	0.119	0.377	0.024	0.48

PWM

	A	C	G	T
01	0.706	-3.066	0.382	-0.769
02	-1.089	-3.362	1.22	-1.422
03	0.779	-0.946	-0.342	-0.326
04	1.34	-3.253	-3.362	-2.243
05	-4.982	1.35	-2.985	-2.45
06	1.09	-2.497	-1.188	-0.449
07	-0.946	-0.283	-0.036	0.639
08	-4.982	0.12	-4.982	1.051
09	0.047	0.23	-0.394	0.02
10	-0.956	-1.201	-2.45	1.172
11	-2.136	-2.243	1.32	-3.484
12	-2.362	-3.066	-2.985	1.337
13	-0.087	-0.283	-0.803	0.632
14	-1.406	1.208	-3.362	-0.988
15	-0.735	0.408	-2.281	0.649

Standard thresholds

P-value	Threshold
0.001	3.42241
0.0005	4.53146
0.0001	6.83281