MotifPRDM1.H12INVIVO.0.S.B
Gene (human)PRDM1
(GeneCards)
Gene synonyms (human)BLIMP1
Gene (mouse)Prdm1
Gene synonyms (mouse)Blimp1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusdRKKGAAAGTdn
GC content39.34%
Information content (bits; total / per base)13.527 / 1.127
Data sourcesHT-SELEX
Aligned words2214

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (35) 0.91 0.98 0.866 0.967 0.895 0.968 4.133 5.277 242.137 588.155
Mouse 13 (72) 0.917 0.973 0.87 0.948 0.915 0.966 4.198 4.995 176.473 634.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.855 0.854 0.756 0.757 0.653 0.669
best 0.991 0.985 0.971 0.96 0.855 0.859
Methyl HT-SELEX, 1 experiments median 0.991 0.985 0.971 0.96 0.855 0.859
best 0.991 0.985 0.971 0.96 0.855 0.859
Non-Methyl HT-SELEX, 3 experiments median 0.745 0.759 0.609 0.633 0.552 0.576
best 0.966 0.948 0.902 0.88 0.755 0.761

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 6.892 5.331 0.152 0.127

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.846 0.64 0.758 0.619
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyPRDM1-like {2.3.3.12} (TFClass)
TFClass IDTFClass: 2.3.3.12.1
HGNCHGNC:9346
MGIMGI:99655
EntrezGene (human)GeneID:639
(SSTAR profile)
EntrezGene (mouse)GeneID:12142
(SSTAR profile)
UniProt ID (human)PRDM1_HUMAN
UniProt ID (mouse)PRDM1_MOUSE
UniProt AC (human)O75626
(TFClass)
UniProt AC (mouse)Q60636
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 13 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011283.0292.0319.0320.0
021584.25162.25257.25210.25
03219.0159.01615.0221.0
04146.0325.0332.01411.0
0520.06.02181.07.0
062211.01.01.01.0
072194.02.014.04.0
082210.00.02.02.0
0916.010.02170.018.0
1033.0108.0148.01925.0
11347.25190.251252.25424.25
12804.75429.75475.75503.75
PFM
ACGT
010.5790.1320.1440.145
020.7160.0730.1160.095
030.0990.0720.7290.1
040.0660.1470.150.637
050.0090.0030.9850.003
060.9990.00.00.0
070.9910.0010.0060.002
080.9980.00.0010.001
090.0070.0050.980.008
100.0150.0490.0670.869
110.1570.0860.5660.192
120.3630.1940.2150.228
PWM
ACGT
010.839-0.636-0.549-0.545
021.049-1.219-0.762-0.962
03-0.922-1.2391.069-0.913
04-1.323-0.53-0.5090.934
05-3.232-4.251.369-4.131
061.382-5.246-5.246-5.246
071.375-4.952-3.552-4.54
081.382-5.664-4.952-4.952
09-3.434-3.8411.364-3.328
10-2.767-1.62-1.311.244
11-0.464-1.0610.814-0.265
120.373-0.252-0.151-0.094
Standard thresholds
P-value Threshold
0.001 3.11931
0.0005 4.42594
0.0001 7.068915