MotifPPARD.H12INVIVO.0.PSM.A
Gene (human)PPARD
(GeneCards)
Gene synonyms (human)NR1C2, PPARB
Gene (mouse)Ppard
Gene synonyms (mouse)Nr1c2, Pparb
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length15
ConsensusbWRGGbSARAGKKYR
GC content51.9%
Information content (bits; total / per base)12.651 / 0.843
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1002

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (12) 0.856 0.884 0.785 0.835 0.852 0.886 3.558 4.134 158.463 213.42

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.954 0.95 0.768 0.782 0.644 0.671
best 0.967 0.962 0.792 0.801 0.661 0.686
Methyl HT-SELEX, 1 experiments median 0.967 0.962 0.792 0.801 0.661 0.686
best 0.967 0.962 0.792 0.801 0.661 0.686
Non-Methyl HT-SELEX, 1 experiments median 0.941 0.939 0.745 0.763 0.626 0.657
best 0.941 0.939 0.745 0.763 0.626 0.657
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyPPAR (NR1C) {2.1.2.5} (TFClass)
TFClass IDTFClass: 2.1.2.5.2
HGNCHGNC:9235
MGIMGI:101884
EntrezGene (human)GeneID:5467
(SSTAR profile)
EntrezGene (mouse)GeneID:19015
(SSTAR profile)
UniProt ID (human)PPARD_HUMAN
UniProt ID (mouse)PPARD_MOUSE
UniProt AC (human)Q03181
(TFClass)
UniProt AC (mouse)P35396
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01107.0393.0374.0128.0
02111.0105.088.0698.0
03495.021.0456.030.0
0478.07.0809.0108.0
05111.016.0838.037.0
06121.0157.0363.0361.0
0760.0554.0279.0109.0
08941.015.033.013.0
09751.033.0185.033.0
10879.01.0114.08.0
1165.05.0914.018.0
1238.011.0761.0192.0
1342.092.0242.0626.0
1473.0638.0140.0151.0
15763.070.086.083.0
PFM
ACGT
010.1070.3920.3730.128
020.1110.1050.0880.697
030.4940.0210.4550.03
040.0780.0070.8070.108
050.1110.0160.8360.037
060.1210.1570.3620.36
070.060.5530.2780.109
080.9390.0150.0330.013
090.750.0330.1850.033
100.8770.0010.1140.008
110.0650.0050.9120.018
120.0380.0110.7590.192
130.0420.0920.2420.625
140.0730.6370.140.151
150.7610.070.0860.083
PWM
ACGT
01-0.8410.4480.399-0.665
02-0.805-0.86-1.0341.02
030.678-2.4070.596-2.073
04-1.152-3.3641.168-0.832
05-0.805-2.6551.203-1.874
06-0.72-0.4630.3690.363
07-1.4080.790.107-0.823
081.318-2.713-1.983-2.841
091.093-1.983-0.301-1.983
101.25-4.527-0.779-3.255
11-1.33-3.6241.289-2.548
12-1.848-2.9871.107-0.264
13-1.752-0.99-0.0340.912
14-1.2160.931-0.576-0.502
151.109-1.257-1.056-1.091
Standard thresholds
P-value Threshold
0.001 4.05801
0.0005 5.01636
0.0001 7.01771