PPARA.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PPARA.H12CORE.0.P.B
Gene (human)	PPARA (GeneCards)
Gene synonyms (human)	NR1C1, PPAR
Gene (mouse)	Ppara
Gene synonyms (mouse)	Nr1c1, Ppar
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	hdbdRGGbvARAGKKSW
GC content	48.98%
Information content (bits; total / per base)	12.081 / 0.711
Data sources	ChIP-Seq
Aligned words	1011

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	19 (106)	0.845	0.937	0.791	0.907	0.836	0.921	3.4	4.47	116.94	350.886

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	Thyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamily	PPAR (NR1C) {2.1.2.5} (TFClass)
TFClass ID	TFClass: 2.1.2.5.1
HGNC	HGNC:9232
MGI	MGI:104740
EntrezGene (human)	GeneID:5465 (SSTAR profile)
EntrezGene (mouse)	GeneID:19013 (SSTAR profile)
UniProt ID (human)	PPARA_HUMAN
UniProt ID (mouse)	PPARA_MOUSE
UniProt AC (human)	Q07869 (TFClass)
UniProt AC (mouse)	P23204 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 19 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	PPARA.H12CORE.0.P.B.pcm
PWM	PPARA.H12CORE.0.P.B.pwm
PFM	PPARA.H12CORE.0.P.B.pfm
Alignment	PPARA.H12CORE.0.P.B.words.tsv
Threshold to P-value map	PPARA.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	PPARA.H12CORE.0.P.B_jaspar_format.txt
MEME format	PPARA.H12CORE.0.P.B_meme_format.meme
Transfac format	PPARA.H12CORE.0.P.B_transfac_format.txt
Homer format	PPARA.H12CORE.0.P.B_homer_format_0.001.txt PPARA.H12CORE.0.P.B_homer_format_0.0005.txt PPARA.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	515.0	237.0	107.0	152.0
02	565.0	81.0	124.0	241.0
03	152.0	385.0	287.0	187.0
04	145.0	118.0	148.0	600.0
05	479.0	26.0	461.0	45.0
06	83.0	5.0	816.0	107.0
07	91.0	35.0	841.0	44.0
08	113.0	162.0	339.0	397.0
09	117.0	551.0	231.0	112.0
10	899.0	44.0	42.0	26.0
11	686.0	42.0	228.0	55.0
12	847.0	6.0	142.0	16.0
13	51.0	4.0	920.0	36.0
14	52.0	17.0	761.0	181.0
15	53.0	108.0	208.0	642.0
16	54.0	637.0	179.0	141.0
17	798.0	54.0	73.0	86.0

PFM

	A	C	G	T
01	0.509	0.234	0.106	0.15
02	0.559	0.08	0.123	0.238
03	0.15	0.381	0.284	0.185
04	0.143	0.117	0.146	0.593
05	0.474	0.026	0.456	0.045
06	0.082	0.005	0.807	0.106
07	0.09	0.035	0.832	0.044
08	0.112	0.16	0.335	0.393
09	0.116	0.545	0.228	0.111
10	0.889	0.044	0.042	0.026
11	0.679	0.042	0.226	0.054
12	0.838	0.006	0.14	0.016
13	0.05	0.004	0.91	0.036
14	0.051	0.017	0.753	0.179
15	0.052	0.107	0.206	0.635
16	0.053	0.63	0.177	0.139
17	0.789	0.053	0.072	0.085

PWM

	A	C	G	T
01	0.708	-0.064	-0.85	-0.504
02	0.801	-1.124	-0.705	-0.047
03	-0.504	0.419	0.126	-0.299
04	-0.551	-0.754	-0.53	0.861
05	0.636	-2.217	0.598	-1.695
06	-1.1	-3.633	1.167	-0.85
07	-1.01	-1.936	1.197	-1.716
08	-0.797	-0.441	0.292	0.449
09	-0.762	0.776	-0.089	-0.805
10	1.264	-1.716	-1.761	-2.217
11	0.994	-1.761	-0.102	-1.501
12	1.205	-3.494	-0.571	-2.664
13	-1.574	-3.794	1.287	-1.909
14	-1.555	-2.609	1.098	-0.331
15	-1.537	-0.841	-0.193	0.928
16	-1.519	0.92	-0.342	-0.578
17	1.145	-1.519	-1.225	-1.065

Standard thresholds

P-value	Threshold
0.001	4.24131
0.0005	5.14176
0.0001	7.03421