| Motif | PO6F1.H12INVITRO.0.SM.B |
| Gene (human) | POU6F1 (GeneCards) |
| Gene synonyms (human) | BRN5, MPOU, TCFB1 |
| Gene (mouse) | Pou6f1 |
| Gene synonyms (mouse) | Emb |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | PO6F1.H12INVITRO.0.SM.B |
| Gene (human) | POU6F1 (GeneCards) |
| Gene synonyms (human) | BRN5, MPOU, TCFB1 |
| Gene (mouse) | Pou6f1 |
| Gene synonyms (mouse) | Emb |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 12 |
| Consensus | nvnTAATGAGbn |
| GC content | 38.31% |
| Information content (bits; total / per base) | 12.634 / 1.053 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 6711 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.978 | 0.963 | 0.958 | 0.938 | 0.914 | 0.89 |
| best | 0.986 | 0.977 | 0.975 | 0.962 | 0.94 | 0.922 | |
| Methyl HT-SELEX, 1 experiments | median | 0.986 | 0.977 | 0.975 | 0.962 | 0.94 | 0.922 |
| best | 0.986 | 0.977 | 0.975 | 0.962 | 0.94 | 0.922 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.969 | 0.949 | 0.941 | 0.915 | 0.888 | 0.858 |
| best | 0.969 | 0.949 | 0.941 | 0.915 | 0.888 | 0.858 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | POU {3.1.10} (TFClass) |
| TF subfamily | POU6 {3.1.10.6} (TFClass) |
| TFClass ID | TFClass: 3.1.10.6.1 |
| HGNC | HGNC:9224 |
| MGI | MGI:102935 |
| EntrezGene (human) | GeneID:5463 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | PO6F1_HUMAN |
| UniProt ID (mouse) | PO6F1_MOUSE |
| UniProt AC (human) | Q14863 (TFClass) |
| UniProt AC (mouse) | Q07916 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | PO6F1.H12INVITRO.0.SM.B.pcm |
| PWM | PO6F1.H12INVITRO.0.SM.B.pwm |
| PFM | PO6F1.H12INVITRO.0.SM.B.pfm |
| Alignment | PO6F1.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | PO6F1.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | PO6F1.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | PO6F1.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | PO6F1.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1601.0 | 1550.0 | 2030.0 | 1530.0 |
| 02 | 1133.5 | 2652.5 | 2454.5 | 470.5 |
| 03 | 2351.0 | 1270.0 | 1495.0 | 1595.0 |
| 04 | 39.0 | 34.0 | 15.0 | 6623.0 |
| 05 | 6707.0 | 0.0 | 0.0 | 4.0 |
| 06 | 6711.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 6.0 | 6705.0 |
| 08 | 3.0 | 3.0 | 5298.0 | 1407.0 |
| 09 | 6689.0 | 12.0 | 3.0 | 7.0 |
| 10 | 212.0 | 658.0 | 5573.0 | 268.0 |
| 11 | 914.75 | 1955.75 | 2811.75 | 1028.75 |
| 12 | 1624.75 | 1338.75 | 1693.75 | 2053.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.239 | 0.231 | 0.302 | 0.228 |
| 02 | 0.169 | 0.395 | 0.366 | 0.07 |
| 03 | 0.35 | 0.189 | 0.223 | 0.238 |
| 04 | 0.006 | 0.005 | 0.002 | 0.987 |
| 05 | 0.999 | 0.0 | 0.0 | 0.001 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.001 | 0.999 |
| 08 | 0.0 | 0.0 | 0.789 | 0.21 |
| 09 | 0.997 | 0.002 | 0.0 | 0.001 |
| 10 | 0.032 | 0.098 | 0.83 | 0.04 |
| 11 | 0.136 | 0.291 | 0.419 | 0.153 |
| 12 | 0.242 | 0.199 | 0.252 | 0.306 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.047 | -0.079 | 0.19 | -0.092 |
| 02 | -0.392 | 0.458 | 0.38 | -1.268 |
| 03 | 0.337 | -0.278 | -0.115 | -0.051 |
| 04 | -3.708 | -3.837 | -4.581 | 1.372 |
| 05 | 1.385 | -6.637 | -6.637 | -5.602 |
| 06 | 1.385 | -6.637 | -6.637 | -6.637 |
| 07 | -6.637 | -6.637 | -5.322 | 1.384 |
| 08 | -5.777 | -5.777 | 1.149 | -0.176 |
| 09 | 1.382 | -4.773 | -5.777 | -5.207 |
| 10 | -2.06 | -0.934 | 1.2 | -1.827 |
| 11 | -0.605 | 0.153 | 0.516 | -0.488 |
| 12 | -0.032 | -0.225 | 0.009 | 0.202 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.296565 |
| 0.0005 | 4.04601 |
| 0.0001 | 7.584785 |