MotifPO6F1.H12CORE.0.SM.B
Gene (human)POU6F1
(GeneCards)
Gene synonyms (human)BRN5, MPOU, TCFB1
Gene (mouse)Pou6f1
Gene synonyms (mouse)Emb
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnvnTAATGAGbn
GC content38.31%
Information content (bits; total / per base)12.634 / 1.053
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6711

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.978 0.963 0.958 0.938 0.914 0.89
best 0.986 0.977 0.975 0.962 0.94 0.922
Methyl HT-SELEX, 1 experiments median 0.986 0.977 0.975 0.962 0.94 0.922
best 0.986 0.977 0.975 0.962 0.94 0.922
Non-Methyl HT-SELEX, 1 experiments median 0.969 0.949 0.941 0.915 0.888 0.858
best 0.969 0.949 0.941 0.915 0.888 0.858
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU6 {3.1.10.6} (TFClass)
TFClass IDTFClass: 3.1.10.6.1
HGNCHGNC:9224
MGIMGI:102935
EntrezGene (human)GeneID:5463
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)PO6F1_HUMAN
UniProt ID (mouse)PO6F1_MOUSE
UniProt AC (human)Q14863
(TFClass)
UniProt AC (mouse)Q07916
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011601.01550.02030.01530.0
021133.52652.52454.5470.5
032351.01270.01495.01595.0
0439.034.015.06623.0
056707.00.00.04.0
066711.00.00.00.0
070.00.06.06705.0
083.03.05298.01407.0
096689.012.03.07.0
10212.0658.05573.0268.0
11914.751955.752811.751028.75
121624.751338.751693.752053.75
PFM
ACGT
010.2390.2310.3020.228
020.1690.3950.3660.07
030.350.1890.2230.238
040.0060.0050.0020.987
050.9990.00.00.001
061.00.00.00.0
070.00.00.0010.999
080.00.00.7890.21
090.9970.0020.00.001
100.0320.0980.830.04
110.1360.2910.4190.153
120.2420.1990.2520.306
PWM
ACGT
01-0.047-0.0790.19-0.092
02-0.3920.4580.38-1.268
030.337-0.278-0.115-0.051
04-3.708-3.837-4.5811.372
051.385-6.637-6.637-5.602
061.385-6.637-6.637-6.637
07-6.637-6.637-5.3221.384
08-5.777-5.7771.149-0.176
091.382-4.773-5.777-5.207
10-2.06-0.9341.2-1.827
11-0.6050.1530.516-0.488
12-0.032-0.2250.0090.202
Standard thresholds
P-value Threshold
0.001 2.296565
0.0005 4.04601
0.0001 7.584785