PO5F1.H12INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO5F1.H12INVIVO.1.P.B
Gene (human)	POU5F1 (GeneCards)
Gene synonyms (human)	OCT3, OCT4, OTF3
Gene (mouse)	Pou5f1
Gene synonyms (mouse)	Oct-3, Oct-4, Otf-3, Otf3
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	WvWhATGYARA
GC content	30.87%
Information content (bits; total / per base)	10.377 / 0.943
Data sources	ChIP-Seq
Aligned words	993

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (161)	0.821	0.917	0.741	0.866	0.84	0.939	3.238	3.949	159.244	367.745
Mouse	124 (789)	0.821	0.909	0.715	0.858	0.827	0.906	2.78	3.765	147.194	399.796

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.994	0.989	0.989	0.982	0.948	0.943
Overall, 2 experiments	best	0.995	0.991	0.994	0.989	0.989	0.982
Methyl HT-SELEX, 1 experiments	median	0.992	0.986	0.983	0.975	0.907	0.903
Methyl HT-SELEX, 1 experiments	best	0.992	0.986	0.983	0.975	0.907	0.903
Non-Methyl HT-SELEX, 1 experiments	median	0.995	0.991	0.994	0.989	0.989	0.982
Non-Methyl HT-SELEX, 1 experiments	best	0.995	0.991	0.994	0.989	0.989	0.982

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU5 {3.1.10.5} (TFClass)
TFClass ID	TFClass: 3.1.10.5.1
HGNC	HGNC:9221
MGI	MGI:101893
EntrezGene (human)	GeneID:5460 (SSTAR profile)
EntrezGene (mouse)	GeneID:18999 (SSTAR profile)
UniProt ID (human)	PO5F1_HUMAN
UniProt ID (mouse)	PO5F1_MOUSE
UniProt AC (human)	Q01860 (TFClass)
UniProt AC (mouse)	P20263 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 124 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	PO5F1.H12INVIVO.1.P.B.pcm
PWM	PO5F1.H12INVIVO.1.P.B.pwm
PFM	PO5F1.H12INVIVO.1.P.B.pfm
Alignment	PO5F1.H12INVIVO.1.P.B.words.tsv
Threshold to P-value map	PO5F1.H12INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	PO5F1.H12INVIVO.1.P.B_jaspar_format.txt
MEME format	PO5F1.H12INVIVO.1.P.B_meme_format.meme
Transfac format	PO5F1.H12INVIVO.1.P.B_transfac_format.txt
Homer format	PO5F1.H12INVIVO.1.P.B_homer_format_0.001.txt PO5F1.H12INVIVO.1.P.B_homer_format_0.0005.txt PO5F1.H12INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	172.0	46.0	149.0	626.0
02	188.0	271.0	412.0	122.0
03	390.0	46.0	45.0	512.0
04	195.0	183.0	79.0	536.0
05	921.0	5.0	28.0	39.0
06	5.0	1.0	20.0	967.0
07	3.0	5.0	845.0	140.0
08	16.0	777.0	74.0	126.0
09	830.0	5.0	14.0	144.0
10	659.0	76.0	190.0	68.0
11	878.0	35.0	66.0	14.0

PFM

	A	C	G	T
01	0.173	0.046	0.15	0.63
02	0.189	0.273	0.415	0.123
03	0.393	0.046	0.045	0.516
04	0.196	0.184	0.08	0.54
05	0.927	0.005	0.028	0.039
06	0.005	0.001	0.02	0.974
07	0.003	0.005	0.851	0.141
08	0.016	0.782	0.075	0.127
09	0.836	0.005	0.014	0.145
10	0.664	0.077	0.191	0.068
11	0.884	0.035	0.066	0.014

PWM

	A	C	G	T
01	-0.364	-1.656	-0.506	0.921
02	-0.276	0.087	0.504	-0.703
03	0.449	-1.656	-1.677	0.72
04	-0.24	-0.302	-1.13	0.766
05	1.306	-3.616	-2.129	-1.815
06	-3.616	-4.519	-2.443	1.355
07	-3.968	-3.616	1.22	-0.567
08	-2.646	1.136	-1.194	-0.671
09	1.202	-3.616	-2.766	-0.54
10	0.972	-1.168	-0.265	-1.277
11	1.258	-1.918	-1.306	-2.766

Standard thresholds

P-value	Threshold
0.001	4.66338
0.0005	5.532105
0.0001	7.308065