MotifPO5F1.H12INVIVO.0.P.B
Gene (human)POU5F1
(GeneCards)
Gene synonyms (human)OCT3, OCT4, OTF3
Gene (mouse)Pou5f1
Gene synonyms (mouse)Oct-3, Oct-4, Otf-3, Otf3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusbbYWTTSWhATGCWdAd
GC content35.41%
Information content (bits; total / per base)14.108 / 0.83
Data sourcesChIP-Seq
Aligned words1022

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 27 (161) 0.883 0.976 0.859 0.956 0.903 0.979 4.874 6.358 235.721 487.046
Mouse 124 (789) 0.888 0.977 0.841 0.974 0.898 0.979 4.222 6.335 213.0 532.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.968 0.95 0.941 0.915 0.88 0.855
best 0.978 0.964 0.96 0.94 0.924 0.898
Methyl HT-SELEX, 1 experiments median 0.958 0.936 0.921 0.89 0.835 0.812
best 0.958 0.936 0.921 0.89 0.835 0.812
Non-Methyl HT-SELEX, 1 experiments median 0.978 0.964 0.96 0.94 0.924 0.898
best 0.978 0.964 0.96 0.94 0.924 0.898
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU5 {3.1.10.5} (TFClass)
TFClass IDTFClass: 3.1.10.5.1
HGNCHGNC:9221
MGIMGI:101893
EntrezGene (human)GeneID:5460
(SSTAR profile)
EntrezGene (mouse)GeneID:18999
(SSTAR profile)
UniProt ID (human)PO5F1_HUMAN
UniProt ID (mouse)PO5F1_MOUSE
UniProt AC (human)Q01860
(TFClass)
UniProt AC (mouse)P20263
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 27 human, 124 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01116.0257.0285.0364.0
0266.0490.0232.0234.0
0353.0606.059.0304.0
04533.033.030.0426.0
0513.038.033.0938.0
0652.014.0130.0826.0
07113.0300.0562.047.0
08344.09.035.0634.0
09160.0258.0110.0494.0
10950.011.027.034.0
119.06.011.0996.0
121.05.0926.090.0
1318.0824.065.0115.0
14776.020.045.0181.0
15573.098.0201.0150.0
16829.042.093.058.0
17169.0136.0161.0556.0
PFM
ACGT
010.1140.2510.2790.356
020.0650.4790.2270.229
030.0520.5930.0580.297
040.5220.0320.0290.417
050.0130.0370.0320.918
060.0510.0140.1270.808
070.1110.2940.550.046
080.3370.0090.0340.62
090.1570.2520.1080.483
100.930.0110.0260.033
110.0090.0060.0110.975
120.0010.0050.9060.088
130.0180.8060.0640.113
140.7590.020.0440.177
150.5610.0960.1970.147
160.8110.0410.0910.057
170.1650.1330.1580.544
PWM
ACGT
01-0.7820.0060.1090.352
02-1.3340.648-0.096-0.087
03-1.5480.86-1.4440.173
040.732-2.002-2.0930.509
05-2.86-1.868-2.0021.296
06-1.566-2.794-0.6691.169
07-0.8070.160.785-1.664
080.296-3.177-1.9460.905
09-0.4640.01-0.8340.656
101.308-3.006-2.192-1.974
11-3.177-3.505-3.0061.356
12-4.545-3.6431.283-1.031
13-2.5681.166-1.349-0.79
141.106-2.471-1.706-0.342
150.804-0.947-0.238-0.528
161.172-1.772-0.999-1.46
17-0.41-0.625-0.4580.774
Standard thresholds
P-value Threshold
0.001 3.52606
0.0005 4.58086
0.0001 6.78836