MotifPO5F1.H12INVITRO.2.SM.B
Gene (human)POU5F1
(GeneCards)
Gene synonyms (human)OCT3, OCT4, OTF3
Gene (mouse)Pou5f1
Gene synonyms (mouse)Oct-3, Oct-4, Otf-3, Otf3
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length17
ConsensusvdWTATGCTAATKARbn
GC content30.29%
Information content (bits; total / per base)21.397 / 1.259
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8781

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 27 (161) 0.688 0.785 0.553 0.689 0.728 0.846 2.316 3.194 42.398 98.658
Mouse 124 (789) 0.676 0.769 0.538 0.672 0.707 0.808 2.167 3.211 47.678 176.569

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 1.0 1.0 1.0 1.0 0.971 0.975
best 1.0 1.0 1.0 1.0 1.0 1.0
Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 1.0 0.942 0.949
best 1.0 1.0 1.0 1.0 0.942 0.949
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 1.0 1.0 1.0
best 1.0 1.0 1.0 1.0 1.0 1.0
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU5 {3.1.10.5} (TFClass)
TFClass IDTFClass: 3.1.10.5.1
HGNCHGNC:9221
MGIMGI:101893
EntrezGene (human)GeneID:5460
(SSTAR profile)
EntrezGene (mouse)GeneID:18999
(SSTAR profile)
UniProt ID (human)PO5F1_HUMAN
UniProt ID (mouse)PO5F1_MOUSE
UniProt AC (human)Q01860
(TFClass)
UniProt AC (mouse)P20263
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 27 human, 124 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013145.752016.752600.751017.75
024565.51044.51781.51389.5
031494.036.0521.06730.0
041.04.02.08774.0
058778.02.01.00.0
065.00.010.08766.0
070.015.08766.00.0
0812.07548.00.01221.0
091709.00.04.07068.0
108775.01.02.03.0
118780.00.00.01.0
120.01.00.08780.0
134.012.03698.05067.0
147983.055.0399.0344.0
153617.0645.04290.0229.0
16397.02150.04565.01669.0
171102.02607.02438.02634.0
PFM
ACGT
010.3580.230.2960.116
020.520.1190.2030.158
030.170.0040.0590.766
040.00.00.00.999
051.00.00.00.0
060.0010.00.0010.998
070.00.0020.9980.0
080.0010.860.00.139
090.1950.00.00.805
100.9990.00.00.0
111.00.00.00.0
120.00.00.01.0
130.00.0010.4210.577
140.9090.0060.0450.039
150.4120.0730.4890.026
160.0450.2450.520.19
170.1250.2970.2780.3
PWM
ACGT
010.359-0.0850.169-0.768
020.732-0.742-0.209-0.457
03-0.384-4.05-1.4351.12
04-6.51-5.859-6.2431.385
051.385-6.243-6.51-6.875
06-5.711-6.875-5.1881.384
07-6.875-4.8461.384-6.875
08-5.0371.234-6.875-0.586
09-0.25-6.875-5.8591.169
101.385-6.51-6.243-6.033
111.385-6.875-6.875-6.51
12-6.875-6.51-6.8751.385
13-5.859-5.0370.5210.836
141.29-3.647-1.7-1.848
150.499-1.2220.669-2.251
16-1.705-0.0210.732-0.274
17-0.6880.1720.1050.182
Standard thresholds
P-value Threshold
0.001 -6.79589
0.0005 -4.49259
0.0001 0.32606