PO5F1.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO5F1.H12INVITRO.1.P.B
Gene (human)	POU5F1 (GeneCards)
Gene synonyms (human)	OCT3, OCT4, OTF3
Gene (mouse)	Pou5f1
Gene synonyms (mouse)	Oct-3, Oct-4, Otf-3, Otf3
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	dhATGYARAWd
GC content	26.8%
Information content (bits; total / per base)	11.416 / 1.038
Data sources	ChIP-Seq
Aligned words	994

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (161)	0.776	0.883	0.664	0.799	0.821	0.933	2.92	3.737	127.523	256.201
Mouse	124 (789)	0.791	0.882	0.666	0.794	0.804	0.884	2.697	3.464	127.215	349.398

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	0.999	0.999	0.999	0.965	0.969
Overall, 2 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.999	0.998	0.93	0.939
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.999	0.998	0.93	0.939
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	0.999	0.999	0.999
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	0.999	0.999	0.999

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU5 {3.1.10.5} (TFClass)
TFClass ID	TFClass: 3.1.10.5.1
HGNC	HGNC:9221
MGI	MGI:101893
EntrezGene (human)	GeneID:5460 (SSTAR profile)
EntrezGene (mouse)	GeneID:18999 (SSTAR profile)
UniProt ID (human)	PO5F1_HUMAN
UniProt ID (mouse)	PO5F1_MOUSE
UniProt AC (human)	Q01860 (TFClass)
UniProt AC (mouse)	P20263 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 124 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	PO5F1.H12INVITRO.1.P.B.pcm
PWM	PO5F1.H12INVITRO.1.P.B.pwm
PFM	PO5F1.H12INVITRO.1.P.B.pfm
Alignment	PO5F1.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	PO5F1.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	PO5F1.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	PO5F1.H12INVITRO.1.P.B_meme_format.meme
Transfac format	PO5F1.H12INVITRO.1.P.B_transfac_format.txt
Homer format	PO5F1.H12INVITRO.1.P.B_homer_format_0.001.txt PO5F1.H12INVITRO.1.P.B_homer_format_0.0005.txt PO5F1.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	410.0	55.0	111.0	418.0
02	237.0	153.0	50.0	554.0
03	948.0	1.0	13.0	32.0
04	7.0	1.0	12.0	974.0
05	0.0	3.0	924.0	67.0
06	23.0	739.0	86.0	146.0
07	748.0	2.0	7.0	237.0
08	771.0	37.0	134.0	52.0
09	961.0	3.0	21.0	9.0
10	164.0	53.0	76.0	701.0
11	177.0	101.0	348.0	368.0

PFM

	A	C	G	T
01	0.412	0.055	0.112	0.421
02	0.238	0.154	0.05	0.557
03	0.954	0.001	0.013	0.032
04	0.007	0.001	0.012	0.98
05	0.0	0.003	0.93	0.067
06	0.023	0.743	0.087	0.147
07	0.753	0.002	0.007	0.238
08	0.776	0.037	0.135	0.052
09	0.967	0.003	0.021	0.009
10	0.165	0.053	0.076	0.705
11	0.178	0.102	0.35	0.37

PWM

	A	C	G	T
01	0.498	-1.484	-0.797	0.517
02	-0.047	-0.481	-1.576	0.798
03	1.334	-4.52	-2.833	-2.004
04	-3.356	-4.52	-2.903	1.361
05	-4.977	-3.969	1.308	-1.292
06	-2.315	1.085	-1.048	-0.527
07	1.097	-4.207	-3.356	-0.047
08	1.128	-1.866	-0.612	-1.538
09	1.347	-3.969	-2.399	-3.15
10	-0.412	-1.52	-1.169	1.033
11	-0.337	-0.89	0.335	0.39

Standard thresholds

P-value	Threshold
0.001	4.339035
0.0005	5.345485
0.0001	7.325055