PO5F1.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO5F1.H12INVITRO.0.P.B
Gene (human)	POU5F1 (GeneCards)
Gene synonyms (human)	OCT3, OCT4, OTF3
Gene (mouse)	Pou5f1
Gene synonyms (mouse)	Oct-3, Oct-4, Otf-3, Otf3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	bhWYWbWhATGYARAWd
GC content	30.48%
Information content (bits; total / per base)	12.503 / 0.735
Data sources	ChIP-Seq
Aligned words	1026

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	27 (161)	0.841	0.945	0.798	0.908	0.884	0.973	4.625	5.837	206.523	429.796
Mouse	124 (789)	0.859	0.965	0.794	0.941	0.886	0.976	4.104	5.679	189.229	503.456

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.993	0.988	0.984	0.977	0.926	0.924
Overall, 2 experiments	best	0.995	0.992	0.991	0.986	0.981	0.973
Methyl HT-SELEX, 1 experiments	median	0.991	0.985	0.977	0.967	0.871	0.874
Methyl HT-SELEX, 1 experiments	best	0.991	0.985	0.977	0.967	0.871	0.874
Non-Methyl HT-SELEX, 1 experiments	median	0.995	0.992	0.991	0.986	0.981	0.973
Non-Methyl HT-SELEX, 1 experiments	best	0.995	0.992	0.991	0.986	0.981	0.973

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU5 {3.1.10.5} (TFClass)
TFClass ID	TFClass: 3.1.10.5.1
HGNC	HGNC:9221
MGI	MGI:101893
EntrezGene (human)	GeneID:5460 (SSTAR profile)
EntrezGene (mouse)	GeneID:18999 (SSTAR profile)
UniProt ID (human)	PO5F1_HUMAN
UniProt ID (mouse)	PO5F1_MOUSE
UniProt AC (human)	Q01860 (TFClass)
UniProt AC (mouse)	P20263 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	27 human, 124 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	PO5F1.H12INVITRO.0.P.B.pcm
PWM	PO5F1.H12INVITRO.0.P.B.pwm
PFM	PO5F1.H12INVITRO.0.P.B.pfm
Alignment	PO5F1.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	PO5F1.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	PO5F1.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	PO5F1.H12INVITRO.0.P.B_meme_format.meme
Transfac format	PO5F1.H12INVITRO.0.P.B_transfac_format.txt
Homer format	PO5F1.H12INVITRO.0.P.B_homer_format_0.001.txt PO5F1.H12INVITRO.0.P.B_homer_format_0.0005.txt PO5F1.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	117.0	373.0	230.0	306.0
02	165.0	460.0	70.0	331.0
03	477.0	57.0	53.0	439.0
04	63.0	113.0	85.0	765.0
05	160.0	39.0	117.0	710.0
06	147.0	331.0	393.0	155.0
07	420.0	37.0	50.0	519.0
08	235.0	173.0	107.0	511.0
09	903.0	11.0	26.0	86.0
10	15.0	3.0	13.0	995.0
11	5.0	10.0	814.0	197.0
12	13.0	714.0	99.0	200.0
13	769.0	12.0	5.0	240.0
14	779.0	32.0	163.0	52.0
15	960.0	14.0	33.0	19.0
16	167.0	75.0	125.0	659.0
17	183.0	158.0	321.0	364.0

PFM

	A	C	G	T
01	0.114	0.364	0.224	0.298
02	0.161	0.448	0.068	0.323
03	0.465	0.056	0.052	0.428
04	0.061	0.11	0.083	0.746
05	0.156	0.038	0.114	0.692
06	0.143	0.323	0.383	0.151
07	0.409	0.036	0.049	0.506
08	0.229	0.169	0.104	0.498
09	0.88	0.011	0.025	0.084
10	0.015	0.003	0.013	0.97
11	0.005	0.01	0.793	0.192
12	0.013	0.696	0.096	0.195
13	0.75	0.012	0.005	0.234
14	0.759	0.031	0.159	0.051
15	0.936	0.014	0.032	0.019
16	0.163	0.073	0.122	0.642
17	0.178	0.154	0.313	0.355

PWM

	A	C	G	T
01	-0.777	0.372	-0.108	0.175
02	-0.437	0.581	-1.281	0.253
03	0.617	-1.481	-1.551	0.535
04	-1.384	-0.811	-1.091	1.088
05	-0.468	-1.847	-0.777	1.014
06	-0.552	0.253	0.424	-0.499
07	0.491	-1.897	-1.608	0.701
08	-0.087	-0.391	-0.865	0.686
09	1.254	-3.01	-2.231	-1.08
10	-2.736	-3.999	-2.864	1.351
11	-3.647	-3.091	1.15	-0.262
12	-2.864	1.019	-0.941	-0.247
13	1.093	-2.934	-3.647	-0.066
14	1.106	-2.035	-0.45	-1.57
15	1.315	-2.798	-2.006	-2.522
16	-0.426	-1.214	-0.712	0.939
17	-0.335	-0.48	0.223	0.348

Standard thresholds

P-value	Threshold
0.001	4.07846
0.0005	5.04926
0.0001	7.06241