Motif | PO5F1.H12CORE.2.SM.B |
Gene (human) | POU5F1 (GeneCards) |
Gene synonyms (human) | OCT3, OCT4, OTF3 |
Gene (mouse) | Pou5f1 |
Gene synonyms (mouse) | Oct-3, Oct-4, Otf-3, Otf3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif | PO5F1.H12CORE.2.SM.B |
Gene (human) | POU5F1 (GeneCards) |
Gene synonyms (human) | OCT3, OCT4, OTF3 |
Gene (mouse) | Pou5f1 |
Gene synonyms (mouse) | Oct-3, Oct-4, Otf-3, Otf3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif length | 17 |
Consensus | vdWTATGCTAATKARbn |
GC content | 30.29% |
Information content (bits; total / per base) | 21.397 / 1.259 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 8781 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 27 (161) | 0.688 | 0.785 | 0.553 | 0.689 | 0.728 | 0.846 | 2.316 | 3.194 | 42.398 | 98.658 |
Mouse | 124 (789) | 0.676 | 0.769 | 0.538 | 0.672 | 0.707 | 0.808 | 2.167 | 3.211 | 47.678 | 176.569 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.971 | 0.975 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.942 | 0.949 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 0.942 | 0.949 | |
Non-Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU5 {3.1.10.5} (TFClass) |
TFClass ID | TFClass: 3.1.10.5.1 |
HGNC | HGNC:9221 |
MGI | MGI:101893 |
EntrezGene (human) | GeneID:5460 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18999 (SSTAR profile) |
UniProt ID (human) | PO5F1_HUMAN |
UniProt ID (mouse) | PO5F1_MOUSE |
UniProt AC (human) | Q01860 (TFClass) |
UniProt AC (mouse) | P20263 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 27 human, 124 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | PO5F1.H12CORE.2.SM.B.pcm |
PWM | PO5F1.H12CORE.2.SM.B.pwm |
PFM | PO5F1.H12CORE.2.SM.B.pfm |
Alignment | PO5F1.H12CORE.2.SM.B.words.tsv |
Threshold to P-value map | PO5F1.H12CORE.2.SM.B.thr |
Motif in other formats | |
JASPAR format | PO5F1.H12CORE.2.SM.B_jaspar_format.txt |
MEME format | PO5F1.H12CORE.2.SM.B_meme_format.meme |
Transfac format | PO5F1.H12CORE.2.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 3145.75 | 2016.75 | 2600.75 | 1017.75 |
02 | 4565.5 | 1044.5 | 1781.5 | 1389.5 |
03 | 1494.0 | 36.0 | 521.0 | 6730.0 |
04 | 1.0 | 4.0 | 2.0 | 8774.0 |
05 | 8778.0 | 2.0 | 1.0 | 0.0 |
06 | 5.0 | 0.0 | 10.0 | 8766.0 |
07 | 0.0 | 15.0 | 8766.0 | 0.0 |
08 | 12.0 | 7548.0 | 0.0 | 1221.0 |
09 | 1709.0 | 0.0 | 4.0 | 7068.0 |
10 | 8775.0 | 1.0 | 2.0 | 3.0 |
11 | 8780.0 | 0.0 | 0.0 | 1.0 |
12 | 0.0 | 1.0 | 0.0 | 8780.0 |
13 | 4.0 | 12.0 | 3698.0 | 5067.0 |
14 | 7983.0 | 55.0 | 399.0 | 344.0 |
15 | 3617.0 | 645.0 | 4290.0 | 229.0 |
16 | 397.0 | 2150.0 | 4565.0 | 1669.0 |
17 | 1102.0 | 2607.0 | 2438.0 | 2634.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.358 | 0.23 | 0.296 | 0.116 |
02 | 0.52 | 0.119 | 0.203 | 0.158 |
03 | 0.17 | 0.004 | 0.059 | 0.766 |
04 | 0.0 | 0.0 | 0.0 | 0.999 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.001 | 0.0 | 0.001 | 0.998 |
07 | 0.0 | 0.002 | 0.998 | 0.0 |
08 | 0.001 | 0.86 | 0.0 | 0.139 |
09 | 0.195 | 0.0 | 0.0 | 0.805 |
10 | 0.999 | 0.0 | 0.0 | 0.0 |
11 | 1.0 | 0.0 | 0.0 | 0.0 |
12 | 0.0 | 0.0 | 0.0 | 1.0 |
13 | 0.0 | 0.001 | 0.421 | 0.577 |
14 | 0.909 | 0.006 | 0.045 | 0.039 |
15 | 0.412 | 0.073 | 0.489 | 0.026 |
16 | 0.045 | 0.245 | 0.52 | 0.19 |
17 | 0.125 | 0.297 | 0.278 | 0.3 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.359 | -0.085 | 0.169 | -0.768 |
02 | 0.732 | -0.742 | -0.209 | -0.457 |
03 | -0.384 | -4.05 | -1.435 | 1.12 |
04 | -6.51 | -5.859 | -6.243 | 1.385 |
05 | 1.385 | -6.243 | -6.51 | -6.875 |
06 | -5.711 | -6.875 | -5.188 | 1.384 |
07 | -6.875 | -4.846 | 1.384 | -6.875 |
08 | -5.037 | 1.234 | -6.875 | -0.586 |
09 | -0.25 | -6.875 | -5.859 | 1.169 |
10 | 1.385 | -6.51 | -6.243 | -6.033 |
11 | 1.385 | -6.875 | -6.875 | -6.51 |
12 | -6.875 | -6.51 | -6.875 | 1.385 |
13 | -5.859 | -5.037 | 0.521 | 0.836 |
14 | 1.29 | -3.647 | -1.7 | -1.848 |
15 | 0.499 | -1.222 | 0.669 | -2.251 |
16 | -1.705 | -0.021 | 0.732 | -0.274 |
17 | -0.688 | 0.172 | 0.105 | 0.182 |
P-value | Threshold |
---|---|
0.001 | -6.79589 |
0.0005 | -4.49259 |
0.0001 | 0.32606 |