Motif | PO5F1.H12CORE.1.P.B |
Gene (human) | POU5F1 (GeneCards) |
Gene synonyms (human) | OCT3, OCT4, OTF3 |
Gene (mouse) | Pou5f1 |
Gene synonyms (mouse) | Oct-3, Oct-4, Otf-3, Otf3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | PO5F1.H12CORE.1.P.B |
Gene (human) | POU5F1 (GeneCards) |
Gene synonyms (human) | OCT3, OCT4, OTF3 |
Gene (mouse) | Pou5f1 |
Gene synonyms (mouse) | Oct-3, Oct-4, Otf-3, Otf3 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 11 |
Consensus | dhATGYARAWd |
GC content | 26.8% |
Information content (bits; total / per base) | 11.416 / 1.038 |
Data sources | ChIP-Seq |
Aligned words | 994 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 27 (161) | 0.776 | 0.883 | 0.664 | 0.799 | 0.821 | 0.933 | 2.92 | 3.737 | 127.523 | 256.201 |
Mouse | 124 (789) | 0.791 | 0.882 | 0.666 | 0.794 | 0.804 | 0.884 | 2.697 | 3.464 | 127.215 | 349.398 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 1.0 | 0.999 | 0.999 | 0.999 | 0.965 | 0.969 |
best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.999 | |
Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.999 | 0.998 | 0.93 | 0.939 |
best | 0.999 | 0.999 | 0.999 | 0.998 | 0.93 | 0.939 | |
Non-Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.999 |
best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.999 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU5 {3.1.10.5} (TFClass) |
TFClass ID | TFClass: 3.1.10.5.1 |
HGNC | HGNC:9221 |
MGI | MGI:101893 |
EntrezGene (human) | GeneID:5460 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18999 (SSTAR profile) |
UniProt ID (human) | PO5F1_HUMAN |
UniProt ID (mouse) | PO5F1_MOUSE |
UniProt AC (human) | Q01860 (TFClass) |
UniProt AC (mouse) | P20263 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 27 human, 124 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | PO5F1.H12CORE.1.P.B.pcm |
PWM | PO5F1.H12CORE.1.P.B.pwm |
PFM | PO5F1.H12CORE.1.P.B.pfm |
Alignment | PO5F1.H12CORE.1.P.B.words.tsv |
Threshold to P-value map | PO5F1.H12CORE.1.P.B.thr |
Motif in other formats | |
JASPAR format | PO5F1.H12CORE.1.P.B_jaspar_format.txt |
MEME format | PO5F1.H12CORE.1.P.B_meme_format.meme |
Transfac format | PO5F1.H12CORE.1.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 410.0 | 55.0 | 111.0 | 418.0 |
02 | 237.0 | 153.0 | 50.0 | 554.0 |
03 | 948.0 | 1.0 | 13.0 | 32.0 |
04 | 7.0 | 1.0 | 12.0 | 974.0 |
05 | 0.0 | 3.0 | 924.0 | 67.0 |
06 | 23.0 | 739.0 | 86.0 | 146.0 |
07 | 748.0 | 2.0 | 7.0 | 237.0 |
08 | 771.0 | 37.0 | 134.0 | 52.0 |
09 | 961.0 | 3.0 | 21.0 | 9.0 |
10 | 164.0 | 53.0 | 76.0 | 701.0 |
11 | 177.0 | 101.0 | 348.0 | 368.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.412 | 0.055 | 0.112 | 0.421 |
02 | 0.238 | 0.154 | 0.05 | 0.557 |
03 | 0.954 | 0.001 | 0.013 | 0.032 |
04 | 0.007 | 0.001 | 0.012 | 0.98 |
05 | 0.0 | 0.003 | 0.93 | 0.067 |
06 | 0.023 | 0.743 | 0.087 | 0.147 |
07 | 0.753 | 0.002 | 0.007 | 0.238 |
08 | 0.776 | 0.037 | 0.135 | 0.052 |
09 | 0.967 | 0.003 | 0.021 | 0.009 |
10 | 0.165 | 0.053 | 0.076 | 0.705 |
11 | 0.178 | 0.102 | 0.35 | 0.37 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.498 | -1.484 | -0.797 | 0.517 |
02 | -0.047 | -0.481 | -1.576 | 0.798 |
03 | 1.334 | -4.52 | -2.833 | -2.004 |
04 | -3.356 | -4.52 | -2.903 | 1.361 |
05 | -4.977 | -3.969 | 1.308 | -1.292 |
06 | -2.315 | 1.085 | -1.048 | -0.527 |
07 | 1.097 | -4.207 | -3.356 | -0.047 |
08 | 1.128 | -1.866 | -0.612 | -1.538 |
09 | 1.347 | -3.969 | -2.399 | -3.15 |
10 | -0.412 | -1.52 | -1.169 | 1.033 |
11 | -0.337 | -0.89 | 0.335 | 0.39 |
P-value | Threshold |
---|---|
0.001 | 4.339035 |
0.0005 | 5.345485 |
0.0001 | 7.325055 |