MotifPO5F1.H12CORE.1.P.B
Gene (human)POU5F1
(GeneCards)
Gene synonyms (human)OCT3, OCT4, OTF3
Gene (mouse)Pou5f1
Gene synonyms (mouse)Oct-3, Oct-4, Otf-3, Otf3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusdhATGYARAWd
GC content26.8%
Information content (bits; total / per base)11.416 / 1.038
Data sourcesChIP-Seq
Aligned words994

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 27 (161) 0.776 0.883 0.664 0.799 0.821 0.933 2.92 3.737 127.523 256.201
Mouse 124 (789) 0.791 0.882 0.666 0.794 0.804 0.884 2.697 3.464 127.215 349.398

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 1.0 0.999 0.999 0.999 0.965 0.969
best 1.0 1.0 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.93 0.939
best 0.999 0.999 0.999 0.998 0.93 0.939
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 0.999 0.999 0.999
best 1.0 1.0 1.0 0.999 0.999 0.999
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU5 {3.1.10.5} (TFClass)
TFClass IDTFClass: 3.1.10.5.1
HGNCHGNC:9221
MGIMGI:101893
EntrezGene (human)GeneID:5460
(SSTAR profile)
EntrezGene (mouse)GeneID:18999
(SSTAR profile)
UniProt ID (human)PO5F1_HUMAN
UniProt ID (mouse)PO5F1_MOUSE
UniProt AC (human)Q01860
(TFClass)
UniProt AC (mouse)P20263
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 27 human, 124 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01410.055.0111.0418.0
02237.0153.050.0554.0
03948.01.013.032.0
047.01.012.0974.0
050.03.0924.067.0
0623.0739.086.0146.0
07748.02.07.0237.0
08771.037.0134.052.0
09961.03.021.09.0
10164.053.076.0701.0
11177.0101.0348.0368.0
PFM
ACGT
010.4120.0550.1120.421
020.2380.1540.050.557
030.9540.0010.0130.032
040.0070.0010.0120.98
050.00.0030.930.067
060.0230.7430.0870.147
070.7530.0020.0070.238
080.7760.0370.1350.052
090.9670.0030.0210.009
100.1650.0530.0760.705
110.1780.1020.350.37
PWM
ACGT
010.498-1.484-0.7970.517
02-0.047-0.481-1.5760.798
031.334-4.52-2.833-2.004
04-3.356-4.52-2.9031.361
05-4.977-3.9691.308-1.292
06-2.3151.085-1.048-0.527
071.097-4.207-3.356-0.047
081.128-1.866-0.612-1.538
091.347-3.969-2.399-3.15
10-0.412-1.52-1.1691.033
11-0.337-0.890.3350.39
Standard thresholds
P-value Threshold
0.001 4.339035
0.0005 5.345485
0.0001 7.325055