PO4F3.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO4F3.H12INVIVO.0.SM.D
Gene (human)	POU4F3 (GeneCards)
Gene synonyms (human)	BRN3C
Gene (mouse)	Pou4f3
Gene synonyms (mouse)	Brn-3.1, Brn-3c, Brn3c
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	17
Consensus	nvvTnAATAATKhAbbn
GC content	28.75%
Information content (bits; total / per base)	15.003 / 0.883
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9842

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.994	0.99	0.986	0.979	0.94	0.925
Overall, 6 experiments	best	0.998	0.998	0.996	0.993	0.989	0.984
Methyl HT-SELEX, 2 experiments	median	0.995	0.992	0.989	0.983	0.962	0.953
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.996	0.993	0.989	0.984
Non-Methyl HT-SELEX, 4 experiments	median	0.99	0.983	0.982	0.972	0.93	0.924
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.998	0.994	0.992	0.971	0.961

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU4 {3.1.10.4} (TFClass)
TFClass ID	TFClass: 3.1.10.4.3
HGNC	HGNC:9220
MGI	MGI:102523
EntrezGene (human)	GeneID:5459 (SSTAR profile)
EntrezGene (mouse)	GeneID:18998 (SSTAR profile)
UniProt ID (human)	PO4F3_HUMAN
UniProt ID (mouse)	PO4F3_MOUSE
UniProt AC (human)	Q15319 (TFClass)
UniProt AC (mouse)	Q63955 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	PO4F3.H12INVIVO.0.SM.D.pcm
PWM	PO4F3.H12INVIVO.0.SM.D.pwm
PFM	PO4F3.H12INVIVO.0.SM.D.pfm
Alignment	PO4F3.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	PO4F3.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	PO4F3.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	PO4F3.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	PO4F3.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	PO4F3.H12INVIVO.0.SM.D_homer_format_0.001.txt PO4F3.H12INVIVO.0.SM.D_homer_format_0.0005.txt PO4F3.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1756.5	2349.5	2378.5	3357.5
02	1780.25	5074.25	1817.25	1170.25
03	5041.0	1579.0	2266.0	956.0
04	38.0	155.0	124.0	9525.0
05	2298.0	1523.0	3627.0	2394.0
06	7575.0	2046.0	100.0	121.0
07	8064.0	154.0	46.0	1578.0
08	58.0	30.0	32.0	9722.0
09	9360.0	482.0	0.0	0.0
10	9675.0	37.0	17.0	113.0
11	469.0	46.0	111.0	9216.0
12	277.0	49.0	2995.0	6521.0
13	2990.0	4245.0	952.0	1655.0
14	9322.0	142.0	305.0	73.0
15	930.0	2337.0	1517.0	5058.0
16	1300.0	1792.0	5022.0	1728.0
17	3390.75	2489.75	2266.75	1694.75

PFM

	A	C	G	T
01	0.178	0.239	0.242	0.341
02	0.181	0.516	0.185	0.119
03	0.512	0.16	0.23	0.097
04	0.004	0.016	0.013	0.968
05	0.233	0.155	0.369	0.243
06	0.77	0.208	0.01	0.012
07	0.819	0.016	0.005	0.16
08	0.006	0.003	0.003	0.988
09	0.951	0.049	0.0	0.0
10	0.983	0.004	0.002	0.011
11	0.048	0.005	0.011	0.936
12	0.028	0.005	0.304	0.663
13	0.304	0.431	0.097	0.168
14	0.947	0.014	0.031	0.007
15	0.094	0.237	0.154	0.514
16	0.132	0.182	0.51	0.176
17	0.345	0.253	0.23	0.172

PWM

	A	C	G	T
01	-0.337	-0.046	-0.034	0.311
02	-0.323	0.723	-0.303	-0.742
03	0.717	-0.443	-0.082	-0.944
04	-4.113	-2.751	-2.97	1.353
05	-0.068	-0.479	0.388	-0.027
06	1.124	-0.184	-3.181	-2.994
07	1.186	-2.757	-3.932	-0.444
08	-3.71	-4.334	-4.274	1.373
09	1.335	-1.626	-6.977	-6.977
10	1.368	-4.138	-4.849	-3.062
11	-1.654	-3.932	-3.079	1.32
12	-2.177	-3.871	0.196	0.974
13	0.195	0.545	-0.948	-0.396
14	1.331	-2.837	-2.081	-3.488
15	-0.971	-0.051	-0.483	0.72
16	-0.637	-0.317	0.713	-0.353
17	0.32	0.012	-0.082	-0.372

Standard thresholds

P-value	Threshold
0.001	2.42221
0.0005	3.73491
0.0001	6.43291