PO4F2.H12INVIVO.0.S.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO4F2.H12INVIVO.0.S.D
Gene (human)	POU4F2 (GeneCards)
Gene synonyms (human)	BRN3B
Gene (mouse)	Pou4f2
Gene synonyms (mouse)	Brn-3.2, Brn3b
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	17
Consensus	nnKhATTAATWATKMWn
GC content	21.35%
Information content (bits; total / per base)	17.202 / 1.012
Data sources	HT-SELEX
Aligned words	8097

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 4 experiments	median	0.894	0.888	0.697	0.724	0.58	0.624
Non-Methyl HT-SELEX, 4 experiments	best	0.996	0.994	0.96	0.955	0.738	0.787

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU4 {3.1.10.4} (TFClass)
TFClass ID	TFClass: 3.1.10.4.2
HGNC	HGNC:9219
MGI	MGI:102524
EntrezGene (human)	GeneID:5458 (SSTAR profile)
EntrezGene (mouse)	GeneID:18997 (SSTAR profile)
UniProt ID (human)	PO4F2_HUMAN
UniProt ID (mouse)	PO4F2_MOUSE
UniProt AC (human)	Q12837 (TFClass)
UniProt AC (mouse)	Q63934 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	0

PCM	PO4F2.H12INVIVO.0.S.D.pcm
PWM	PO4F2.H12INVIVO.0.S.D.pwm
PFM	PO4F2.H12INVIVO.0.S.D.pfm
Alignment	PO4F2.H12INVIVO.0.S.D.words.tsv
Threshold to P-value map	PO4F2.H12INVIVO.0.S.D.thr
Motif in other formats
JASPAR format	PO4F2.H12INVIVO.0.S.D_jaspar_format.txt
MEME format	PO4F2.H12INVIVO.0.S.D_meme_format.meme
Transfac format	PO4F2.H12INVIVO.0.S.D_transfac_format.txt
Homer format	PO4F2.H12INVIVO.0.S.D_homer_format_0.001.txt PO4F2.H12INVIVO.0.S.D_homer_format_0.0005.txt PO4F2.H12INVIVO.0.S.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2177.25	1816.25	2238.25	1865.25
02	1263.25	2442.25	1806.25	2585.25
03	984.0	831.0	1389.0	4893.0
04	2147.0	4282.0	603.0	1065.0
05	7427.0	202.0	246.0	222.0
06	9.0	10.0	7.0	8071.0
07	505.0	30.0	1152.0	6410.0
08	7762.0	146.0	1.0	188.0
09	7803.0	3.0	18.0	273.0
10	132.0	34.0	37.0	7894.0
11	3227.0	24.0	61.0	4785.0
12	7974.0	29.0	15.0	79.0
13	377.0	52.0	90.0	7578.0
14	235.0	93.0	2281.0	5488.0
15	1888.0	4688.0	339.0	1182.0
16	6206.0	581.0	626.0	684.0
17	1858.5	1739.5	1472.5	3026.5

PFM

	A	C	G	T
01	0.269	0.224	0.276	0.23
02	0.156	0.302	0.223	0.319
03	0.122	0.103	0.172	0.604
04	0.265	0.529	0.074	0.132
05	0.917	0.025	0.03	0.027
06	0.001	0.001	0.001	0.997
07	0.062	0.004	0.142	0.792
08	0.959	0.018	0.0	0.023
09	0.964	0.0	0.002	0.034
10	0.016	0.004	0.005	0.975
11	0.399	0.003	0.008	0.591
12	0.985	0.004	0.002	0.01
13	0.047	0.006	0.011	0.936
14	0.029	0.011	0.282	0.678
15	0.233	0.579	0.042	0.146
16	0.766	0.072	0.077	0.084
17	0.23	0.215	0.182	0.374

PWM

	A	C	G	T
01	0.073	-0.108	0.1	-0.082
02	-0.471	0.188	-0.114	0.244
03	-0.72	-0.889	-0.376	0.882
04	0.059	0.749	-1.208	-0.641
05	1.299	-2.295	-2.1	-2.201
06	-5.194	-5.109	-5.389	1.382
07	-1.385	-4.141	-0.563	1.152
08	1.343	-2.615	-6.435	-2.366
09	1.348	-5.956	-4.606	-1.996
10	-2.714	-4.024	-3.944	1.36
11	0.466	-4.346	-3.467	0.86
12	1.37	-4.172	-4.766	-3.217
13	-1.676	-3.62	-3.09	1.319
14	-2.145	-3.058	0.119	0.997
15	-0.07	0.839	-1.781	-0.537
16	1.12	-1.245	-1.171	-1.083
17	-0.085	-0.151	-0.318	0.402

Standard thresholds

P-value	Threshold
0.001	1.16366
0.0005	2.59881
0.0001	5.59146