MotifPO4F1.H12INVIVO.0.S.D
Gene (human)POU4F1
(GeneCards)
Gene synonyms (human)BRN3A, RDC1
Gene (mouse)Pou4f1
Gene synonyms (mouse)Brn-3, Brn3, Brn3a
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length13
ConsensusnvWTWATKMAYdn
GC content30.05%
Information content (bits; total / per base)11.209 / 0.862
Data sourcesHT-SELEX
Aligned words9462

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.981 0.972 0.951 0.934 0.859 0.852
best 0.99 0.983 0.977 0.966 0.954 0.936
Methyl HT-SELEX, 1 experiments median 0.99 0.983 0.977 0.966 0.954 0.936
best 0.99 0.983 0.977 0.966 0.954 0.936
Non-Methyl HT-SELEX, 3 experiments median 0.977 0.964 0.943 0.929 0.791 0.804
best 0.986 0.979 0.959 0.938 0.928 0.901
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU4 {3.1.10.4} (TFClass)
TFClass IDTFClass: 3.1.10.4.1
HGNCHGNC:9218
MGIMGI:102525
EntrezGene (human)GeneID:5457
(SSTAR profile)
EntrezGene (mouse)GeneID:18996
(SSTAR profile)
UniProt ID (human)PO4F1_HUMAN
UniProt ID (mouse)PO4F1_MOUSE
UniProt AC (human)Q01851
(TFClass)
UniProt AC (mouse)P17208
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012136.251941.252644.252740.25
024154.253103.251233.25971.25
035725.01158.0864.01715.0
04329.0112.0484.08537.0
053681.01214.0192.04375.0
069444.07.00.011.0
070.032.011.09419.0
085.00.04830.04627.0
093122.05974.088.0278.0
109322.027.0108.05.0
11391.01301.0854.06916.0
121343.51296.54790.52031.5
132793.02758.01940.01971.0
PFM
ACGT
010.2260.2050.2790.29
020.4390.3280.130.103
030.6050.1220.0910.181
040.0350.0120.0510.902
050.3890.1280.020.462
060.9980.0010.00.001
070.00.0030.0010.995
080.0010.00.510.489
090.330.6310.0090.029
100.9850.0030.0110.001
110.0410.1370.090.731
120.1420.1370.5060.215
130.2950.2910.2050.208
PWM
ACGT
01-0.102-0.1970.1110.147
020.5630.271-0.65-0.889
030.883-0.713-1.005-0.321
04-1.967-3.031-1.5831.283
050.442-0.666-2.50.614
061.384-5.541-6.942-5.183
07-6.942-4.235-5.1831.381
08-5.783-6.9420.7130.67
090.2770.926-3.267-2.134
101.371-4.393-3.067-5.783
11-1.795-0.597-1.0171.072
12-0.565-0.6010.705-0.152
130.1660.153-0.198-0.182
Standard thresholds
P-value Threshold
0.001 4.33571
0.0005 5.46586
0.0001 7.54862