PO4F1.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO4F1.H12INVITRO.0.S.B
Gene (human)	POU4F1 (GeneCards)
Gene synonyms (human)	BRN3A, RDC1
Gene (mouse)	Pou4f1
Gene synonyms (mouse)	Brn-3, Brn3, Brn3a
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nvWTWATKMAYdn
GC content	30.05%
Information content (bits; total / per base)	11.209 / 0.862
Data sources	HT-SELEX
Aligned words	9462

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.981	0.972	0.951	0.934	0.859	0.852
Overall, 4 experiments	best	0.99	0.983	0.977	0.966	0.954	0.936
Methyl HT-SELEX, 1 experiments	median	0.99	0.983	0.977	0.966	0.954	0.936
Methyl HT-SELEX, 1 experiments	best	0.99	0.983	0.977	0.966	0.954	0.936
Non-Methyl HT-SELEX, 3 experiments	median	0.977	0.964	0.943	0.929	0.791	0.804
Non-Methyl HT-SELEX, 3 experiments	best	0.986	0.979	0.959	0.938	0.928	0.901

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU4 {3.1.10.4} (TFClass)
TFClass ID	TFClass: 3.1.10.4.1
HGNC	HGNC:9218
MGI	MGI:102525
EntrezGene (human)	GeneID:5457 (SSTAR profile)
EntrezGene (mouse)	GeneID:18996 (SSTAR profile)
UniProt ID (human)	PO4F1_HUMAN
UniProt ID (mouse)	PO4F1_MOUSE
UniProt AC (human)	Q01851 (TFClass)
UniProt AC (mouse)	P17208 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	PO4F1.H12INVITRO.0.S.B.pcm
PWM	PO4F1.H12INVITRO.0.S.B.pwm
PFM	PO4F1.H12INVITRO.0.S.B.pfm
Alignment	PO4F1.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	PO4F1.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	PO4F1.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	PO4F1.H12INVITRO.0.S.B_meme_format.meme
Transfac format	PO4F1.H12INVITRO.0.S.B_transfac_format.txt
Homer format	PO4F1.H12INVITRO.0.S.B_homer_format_0.001.txt PO4F1.H12INVITRO.0.S.B_homer_format_0.0005.txt PO4F1.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2136.25	1941.25	2644.25	2740.25
02	4154.25	3103.25	1233.25	971.25
03	5725.0	1158.0	864.0	1715.0
04	329.0	112.0	484.0	8537.0
05	3681.0	1214.0	192.0	4375.0
06	9444.0	7.0	0.0	11.0
07	0.0	32.0	11.0	9419.0
08	5.0	0.0	4830.0	4627.0
09	3122.0	5974.0	88.0	278.0
10	9322.0	27.0	108.0	5.0
11	391.0	1301.0	854.0	6916.0
12	1343.5	1296.5	4790.5	2031.5
13	2793.0	2758.0	1940.0	1971.0

PFM

	A	C	G	T
01	0.226	0.205	0.279	0.29
02	0.439	0.328	0.13	0.103
03	0.605	0.122	0.091	0.181
04	0.035	0.012	0.051	0.902
05	0.389	0.128	0.02	0.462
06	0.998	0.001	0.0	0.001
07	0.0	0.003	0.001	0.995
08	0.001	0.0	0.51	0.489
09	0.33	0.631	0.009	0.029
10	0.985	0.003	0.011	0.001
11	0.041	0.137	0.09	0.731
12	0.142	0.137	0.506	0.215
13	0.295	0.291	0.205	0.208

PWM

	A	C	G	T
01	-0.102	-0.197	0.111	0.147
02	0.563	0.271	-0.65	-0.889
03	0.883	-0.713	-1.005	-0.321
04	-1.967	-3.031	-1.583	1.283
05	0.442	-0.666	-2.5	0.614
06	1.384	-5.541	-6.942	-5.183
07	-6.942	-4.235	-5.183	1.381
08	-5.783	-6.942	0.713	0.67
09	0.277	0.926	-3.267	-2.134
10	1.371	-4.393	-3.067	-5.783
11	-1.795	-0.597	-1.017	1.072
12	-0.565	-0.601	0.705	-0.152
13	0.166	0.153	-0.198	-0.182

Standard thresholds

P-value	Threshold
0.001	4.33571
0.0005	5.46586
0.0001	7.54862