MotifPO4F1.H12CORE.1.SM.B
Gene (human)POU4F1
(GeneCards)
Gene synonyms (human)BRN3A, RDC1
Gene (mouse)Pou4f1
Gene synonyms (mouse)Brn-3, Brn3, Brn3a
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length17
ConsensushvRTWAATWATKMAbdn
GC content25.57%
Information content (bits; total / per base)16.222 / 0.954
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7448

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.985 0.975 0.951 0.936 0.835 0.839
best 0.995 0.992 0.99 0.985 0.977 0.968
Methyl HT-SELEX, 1 experiments median 0.995 0.992 0.99 0.985 0.977 0.968
best 0.995 0.992 0.99 0.985 0.977 0.968
Non-Methyl HT-SELEX, 3 experiments median 0.975 0.958 0.944 0.935 0.751 0.786
best 0.994 0.991 0.957 0.938 0.919 0.891
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU4 {3.1.10.4} (TFClass)
TFClass IDTFClass: 3.1.10.4.1
HGNCHGNC:9218
MGIMGI:102525
EntrezGene (human)GeneID:5457
(SSTAR profile)
EntrezGene (mouse)GeneID:18996
(SSTAR profile)
UniProt ID (human)PO4F1_HUMAN
UniProt ID (mouse)PO4F1_MOUSE
UniProt AC (human)Q01851
(TFClass)
UniProt AC (mouse)P17208
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011484.251373.251342.253248.25
022167.03491.0948.0842.0
035319.0743.0850.0536.0
0458.059.068.07263.0
05930.0579.0761.05178.0
066915.0337.025.0171.0
076393.054.029.0972.0
08109.037.086.07216.0
092402.0164.086.04796.0
107407.012.011.018.0
11127.075.080.07166.0
1233.029.03828.03558.0
13896.05816.0265.0471.0
146317.0163.0909.059.0
15654.01556.01123.04115.0
161517.251184.253075.251671.25
172534.751724.751492.751695.75
PFM
ACGT
010.1990.1840.180.436
020.2910.4690.1270.113
030.7140.10.1140.072
040.0080.0080.0090.975
050.1250.0780.1020.695
060.9280.0450.0030.023
070.8580.0070.0040.131
080.0150.0050.0120.969
090.3230.0220.0120.644
100.9940.0020.0010.002
110.0170.010.0110.962
120.0040.0040.5140.478
130.120.7810.0360.063
140.8480.0220.1220.008
150.0880.2090.1510.552
160.2040.1590.4130.224
170.340.2320.20.228
PWM
ACGT
01-0.226-0.304-0.3270.556
020.1520.628-0.674-0.792
031.049-0.917-0.783-1.242
04-3.432-3.416-3.2791.36
05-0.693-1.165-0.8931.022
061.311-1.704-4.226-2.376
071.233-3.501-4.089-0.649
08-2.819-3.861-3.0511.354
090.254-2.417-3.0510.945
101.38-4.875-4.948-4.523
11-2.669-3.184-3.1211.347
12-3.969-4.0890.720.647
13-0.731.138-1.942-1.371
141.221-2.423-0.716-3.416
15-1.044-0.179-0.5050.792
16-0.204-0.4520.501-0.108
170.308-0.076-0.221-0.093
Standard thresholds
P-value Threshold
0.001 2.05181
0.0005 3.35826
0.0001 6.08156