Motif | PO4F1.H12CORE.1.SM.B |
Gene (human) | POU4F1 (GeneCards) |
Gene synonyms (human) | BRN3A, RDC1 |
Gene (mouse) | Pou4f1 |
Gene synonyms (mouse) | Brn-3, Brn3, Brn3a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | PO4F1.H12CORE.1.SM.B |
Gene (human) | POU4F1 (GeneCards) |
Gene synonyms (human) | BRN3A, RDC1 |
Gene (mouse) | Pou4f1 |
Gene synonyms (mouse) | Brn-3, Brn3, Brn3a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 17 |
Consensus | hvRTWAATWATKMAbdn |
GC content | 25.57% |
Information content (bits; total / per base) | 16.222 / 0.954 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 7448 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.985 | 0.975 | 0.951 | 0.936 | 0.835 | 0.839 |
best | 0.995 | 0.992 | 0.99 | 0.985 | 0.977 | 0.968 | |
Methyl HT-SELEX, 1 experiments | median | 0.995 | 0.992 | 0.99 | 0.985 | 0.977 | 0.968 |
best | 0.995 | 0.992 | 0.99 | 0.985 | 0.977 | 0.968 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.975 | 0.958 | 0.944 | 0.935 | 0.751 | 0.786 |
best | 0.994 | 0.991 | 0.957 | 0.938 | 0.919 | 0.891 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU4 {3.1.10.4} (TFClass) |
TFClass ID | TFClass: 3.1.10.4.1 |
HGNC | HGNC:9218 |
MGI | MGI:102525 |
EntrezGene (human) | GeneID:5457 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18996 (SSTAR profile) |
UniProt ID (human) | PO4F1_HUMAN |
UniProt ID (mouse) | PO4F1_MOUSE |
UniProt AC (human) | Q01851 (TFClass) |
UniProt AC (mouse) | P17208 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | PO4F1.H12CORE.1.SM.B.pcm |
PWM | PO4F1.H12CORE.1.SM.B.pwm |
PFM | PO4F1.H12CORE.1.SM.B.pfm |
Alignment | PO4F1.H12CORE.1.SM.B.words.tsv |
Threshold to P-value map | PO4F1.H12CORE.1.SM.B.thr |
Motif in other formats | |
JASPAR format | PO4F1.H12CORE.1.SM.B_jaspar_format.txt |
MEME format | PO4F1.H12CORE.1.SM.B_meme_format.meme |
Transfac format | PO4F1.H12CORE.1.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1484.25 | 1373.25 | 1342.25 | 3248.25 |
02 | 2167.0 | 3491.0 | 948.0 | 842.0 |
03 | 5319.0 | 743.0 | 850.0 | 536.0 |
04 | 58.0 | 59.0 | 68.0 | 7263.0 |
05 | 930.0 | 579.0 | 761.0 | 5178.0 |
06 | 6915.0 | 337.0 | 25.0 | 171.0 |
07 | 6393.0 | 54.0 | 29.0 | 972.0 |
08 | 109.0 | 37.0 | 86.0 | 7216.0 |
09 | 2402.0 | 164.0 | 86.0 | 4796.0 |
10 | 7407.0 | 12.0 | 11.0 | 18.0 |
11 | 127.0 | 75.0 | 80.0 | 7166.0 |
12 | 33.0 | 29.0 | 3828.0 | 3558.0 |
13 | 896.0 | 5816.0 | 265.0 | 471.0 |
14 | 6317.0 | 163.0 | 909.0 | 59.0 |
15 | 654.0 | 1556.0 | 1123.0 | 4115.0 |
16 | 1517.25 | 1184.25 | 3075.25 | 1671.25 |
17 | 2534.75 | 1724.75 | 1492.75 | 1695.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.199 | 0.184 | 0.18 | 0.436 |
02 | 0.291 | 0.469 | 0.127 | 0.113 |
03 | 0.714 | 0.1 | 0.114 | 0.072 |
04 | 0.008 | 0.008 | 0.009 | 0.975 |
05 | 0.125 | 0.078 | 0.102 | 0.695 |
06 | 0.928 | 0.045 | 0.003 | 0.023 |
07 | 0.858 | 0.007 | 0.004 | 0.131 |
08 | 0.015 | 0.005 | 0.012 | 0.969 |
09 | 0.323 | 0.022 | 0.012 | 0.644 |
10 | 0.994 | 0.002 | 0.001 | 0.002 |
11 | 0.017 | 0.01 | 0.011 | 0.962 |
12 | 0.004 | 0.004 | 0.514 | 0.478 |
13 | 0.12 | 0.781 | 0.036 | 0.063 |
14 | 0.848 | 0.022 | 0.122 | 0.008 |
15 | 0.088 | 0.209 | 0.151 | 0.552 |
16 | 0.204 | 0.159 | 0.413 | 0.224 |
17 | 0.34 | 0.232 | 0.2 | 0.228 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.226 | -0.304 | -0.327 | 0.556 |
02 | 0.152 | 0.628 | -0.674 | -0.792 |
03 | 1.049 | -0.917 | -0.783 | -1.242 |
04 | -3.432 | -3.416 | -3.279 | 1.36 |
05 | -0.693 | -1.165 | -0.893 | 1.022 |
06 | 1.311 | -1.704 | -4.226 | -2.376 |
07 | 1.233 | -3.501 | -4.089 | -0.649 |
08 | -2.819 | -3.861 | -3.051 | 1.354 |
09 | 0.254 | -2.417 | -3.051 | 0.945 |
10 | 1.38 | -4.875 | -4.948 | -4.523 |
11 | -2.669 | -3.184 | -3.121 | 1.347 |
12 | -3.969 | -4.089 | 0.72 | 0.647 |
13 | -0.73 | 1.138 | -1.942 | -1.371 |
14 | 1.221 | -2.423 | -0.716 | -3.416 |
15 | -1.044 | -0.179 | -0.505 | 0.792 |
16 | -0.204 | -0.452 | 0.501 | -0.108 |
17 | 0.308 | -0.076 | -0.221 | -0.093 |
P-value | Threshold |
---|---|
0.001 | 2.05181 |
0.0005 | 3.35826 |
0.0001 | 6.08156 |