MotifPO3F4.H12CORE.0.SM.B
Gene (human)POU3F4
(GeneCards)
Gene synonyms (human)BRN4, OTF9
Gene (mouse)Pou3f4
Gene synonyms (mouse)Brn-4, Brn4, Otf9
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length15
ConsensusnYTMATTWGCATAWh
GC content29.74%
Information content (bits; total / per base)19.548 / 1.303
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7817

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.996 0.995 0.962 0.956 0.861 0.86
best 1.0 1.0 0.999 0.999 0.972 0.97
Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.999 0.999 0.972 0.97
best 1.0 1.0 0.999 0.999 0.972 0.97
Non-Methyl HT-SELEX, 3 experiments median 0.995 0.994 0.941 0.934 0.807 0.813
best 0.997 0.996 0.983 0.978 0.914 0.906
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.4
HGNCHGNC:9217
MGIMGI:101894
EntrezGene (human)GeneID:5456
(SSTAR profile)
EntrezGene (mouse)GeneID:18994
(SSTAR profile)
UniProt ID (human)PO3F4_HUMAN
UniProt ID (mouse)PO3F4_MOUSE
UniProt AC (human)P49335
(TFClass)
UniProt AC (mouse)P62515
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011583.02822.02035.01377.0
02429.05636.0644.01108.0
03242.0108.0137.07330.0
044365.03265.0111.076.0
057792.011.010.04.0
060.09.05.07803.0
0717.010.066.07724.0
084940.077.00.02800.0
09332.075.07402.08.0
106.07748.017.046.0
117710.023.048.036.0
1242.061.023.07691.0
137274.083.0203.0257.0
144945.751010.75227.751632.75
151587.51547.51452.53229.5
PFM
ACGT
010.2030.3610.260.176
020.0550.7210.0820.142
030.0310.0140.0180.938
040.5580.4180.0140.01
050.9970.0010.0010.001
060.00.0010.0010.998
070.0020.0010.0080.988
080.6320.010.00.358
090.0420.010.9470.001
100.0010.9910.0020.006
110.9860.0030.0060.005
120.0050.0080.0030.984
130.9310.0110.0260.033
140.6330.1290.0290.209
150.2030.1980.1860.413
PWM
ACGT
01-0.210.3670.04-0.35
02-1.5121.058-1.108-0.567
03-2.081-2.876-2.6431.321
040.8030.513-2.849-3.219
051.382-4.996-5.074-5.748
06-6.772-5.159-5.5991.384
07-4.622-5.074-3.3561.373
080.927-3.206-6.7720.359
09-1.767-3.2321.331-5.253
10-5.471.377-4.622-3.703
111.372-4.35-3.662-3.935
12-3.789-3.432-4.351.369
131.313-3.133-2.255-2.021
140.928-0.658-2.141-0.18
15-0.208-0.233-0.2960.502
Standard thresholds
P-value Threshold
0.001 -1.46569
0.0005 0.23451
0.0001 3.84571