PO3F3.H12RSNP.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F3.H12RSNP.0.P.D
Gene (human)	POU3F3 (GeneCards)
Gene synonyms (human)	BRN1, OTF8
Gene (mouse)	Pou3f3
Gene synonyms (mouse)	Brn-1, Brn1, Otf8
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	bdhATGMAWAWK
GC content	30.96%
Information content (bits; total / per base)	11.048 / 0.921
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.814	0.827	0.739	0.749	0.82	0.834	3.415	3.534	230.77	239.155

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.768	0.718	0.69	0.657	0.617	0.606
Non-Methyl HT-SELEX, 2 experiments	best	0.848	0.799	0.754	0.718	0.655	0.646

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.3
HGNC	HGNC:9216
MGI	MGI:102564
EntrezGene (human)	GeneID:5455 (SSTAR profile)
EntrezGene (mouse)	GeneID:18993 (SSTAR profile)
UniProt ID (human)	PO3F3_HUMAN
UniProt ID (mouse)	PO3F3_MOUSE
UniProt AC (human)	P20264 (TFClass)
UniProt AC (mouse)	P31361 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	PO3F3.H12RSNP.0.P.D.pcm
PWM	PO3F3.H12RSNP.0.P.D.pwm
PFM	PO3F3.H12RSNP.0.P.D.pfm
Alignment	PO3F3.H12RSNP.0.P.D.words.tsv
Threshold to P-value map	PO3F3.H12RSNP.0.P.D.thr
Motif in other formats
JASPAR format	PO3F3.H12RSNP.0.P.D_jaspar_format.txt
MEME format	PO3F3.H12RSNP.0.P.D_meme_format.meme
Transfac format	PO3F3.H12RSNP.0.P.D_transfac_format.txt
Homer format	PO3F3.H12RSNP.0.P.D_homer_format_0.001.txt PO3F3.H12RSNP.0.P.D_homer_format_0.0005.txt PO3F3.H12RSNP.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	124.0	388.0	245.0	239.0
02	204.0	91.0	177.0	524.0
03	143.0	554.0	84.0	215.0
04	927.0	48.0	2.0	19.0
05	6.0	1.0	10.0	979.0
06	39.0	16.0	908.0	33.0
07	350.0	551.0	42.0	53.0
08	827.0	17.0	2.0	150.0
09	401.0	11.0	59.0	525.0
10	913.0	31.0	14.0	38.0
11	211.0	22.0	39.0	724.0
12	39.0	52.0	336.0	569.0

PFM

	A	C	G	T
01	0.124	0.39	0.246	0.24
02	0.205	0.091	0.178	0.526
03	0.144	0.556	0.084	0.216
04	0.931	0.048	0.002	0.019
05	0.006	0.001	0.01	0.983
06	0.039	0.016	0.912	0.033
07	0.351	0.553	0.042	0.053
08	0.83	0.017	0.002	0.151
09	0.403	0.011	0.059	0.527
10	0.917	0.031	0.014	0.038
11	0.212	0.022	0.039	0.727
12	0.039	0.052	0.337	0.571

PWM

	A	C	G	T
01	-0.69	0.441	-0.016	-0.041
02	-0.198	-0.995	-0.339	0.74
03	-0.55	0.796	-1.073	-0.146
04	1.309	-1.618	-4.209	-2.493
05	-3.48	-4.522	-3.063	1.364
06	-1.817	-2.649	1.289	-1.977
07	0.338	0.791	-1.746	-1.522
08	1.196	-2.594	-4.209	-0.502
09	0.474	-2.981	-1.418	0.742
10	1.294	-2.036	-2.769	-1.842
11	-0.164	-2.358	-1.817	1.063
12	-1.817	-1.54	0.298	0.823

Standard thresholds

P-value	Threshold
0.001	4.462765
0.0005	5.39167
0.0001	7.285435