MotifPO3F3.H12INVIVO.2.S.B
Gene (human)POU3F3
(GeneCards)
Gene synonyms (human)BRN1, OTF8
Gene (mouse)Pou3f3
Gene synonyms (mouse)Brn-1, Brn1, Otf8
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length12
ConsensusdbvhTAATTWRn
GC content24.3%
Information content (bits; total / per base)11.392 / 0.949
Data sourcesHT-SELEX
Aligned words6799

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.661 0.671 0.474 0.482 0.671 0.684 1.906 1.941 44.119 50.721

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.779 0.727 0.7 0.667 0.627 0.615
best 0.875 0.818 0.787 0.745 0.681 0.668
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.3
HGNCHGNC:9216
MGIMGI:102564
EntrezGene (human)GeneID:5455
(SSTAR profile)
EntrezGene (mouse)GeneID:18993
(SSTAR profile)
UniProt ID (human)PO3F3_HUMAN
UniProt ID (mouse)PO3F3_MOUSE
UniProt AC (human)P20264
(TFClass)
UniProt AC (mouse)P31361
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
011672.25994.251063.253069.25
02854.251094.252673.252177.25
032360.02369.01904.0166.0
042209.02323.0301.01966.0
050.00.00.06799.0
066777.022.00.00.0
076799.00.00.00.0
080.00.00.06799.0
090.029.01267.05503.0
104961.0803.051.0984.0
113984.5902.51485.5426.5
121978.51359.51180.52280.5
PFM
ACGT
010.2460.1460.1560.451
020.1260.1610.3930.32
030.3470.3480.280.024
040.3250.3420.0440.289
050.00.00.01.0
060.9970.0030.00.0
071.00.00.00.0
080.00.00.01.0
090.00.0040.1860.809
100.730.1180.0080.145
110.5860.1330.2180.063
120.2910.20.1740.335
PWM
ACGT
01-0.016-0.535-0.4680.59
02-0.687-0.440.4520.247
030.3280.3320.113-2.314
040.2620.312-1.7250.145
05-6.648-6.648-6.6481.385
061.382-4.253-6.648-6.648
071.385-6.648-6.648-6.648
08-6.648-6.648-6.6481.385
09-6.648-3.999-0.2931.174
101.07-0.748-3.465-0.546
110.851-0.632-0.135-1.379
120.152-0.223-0.3640.294
Standard thresholds
P-value Threshold
0.001 3.987275
0.0005 5.62935
0.0001 7.704395