PO3F3.H12INVIVO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F3.H12INVIVO.1.P.C
Gene (human)	POU3F3 (GeneCards)
Gene synonyms (human)	BRN1, OTF8
Gene (mouse)	Pou3f3
Gene synonyms (mouse)	Brn-1, Brn1, Otf8
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	18
Consensus	bhYWTGMATWWdnMWdvv
GC content	34.88%
Information content (bits; total / per base)	11.53 / 0.641
Data sources	ChIP-Seq
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (7)	0.812	0.82	0.743	0.76	0.828	0.837	3.998	4.098	242.553	255.585

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.749	0.711	0.66	0.639	0.589	0.589
Non-Methyl HT-SELEX, 2 experiments	best	0.836	0.798	0.722	0.699	0.623	0.626

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.3
HGNC	HGNC:9216
MGI	MGI:102564
EntrezGene (human)	GeneID:5455 (SSTAR profile)
EntrezGene (mouse)	GeneID:18993 (SSTAR profile)
UniProt ID (human)	PO3F3_HUMAN
UniProt ID (mouse)	PO3F3_MOUSE
UniProt AC (human)	P20264 (TFClass)
UniProt AC (mouse)	P31361 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	PO3F3.H12INVIVO.1.P.C.pcm
PWM	PO3F3.H12INVIVO.1.P.C.pwm
PFM	PO3F3.H12INVIVO.1.P.C.pfm
Alignment	PO3F3.H12INVIVO.1.P.C.words.tsv
Threshold to P-value map	PO3F3.H12INVIVO.1.P.C.thr
Motif in other formats
JASPAR format	PO3F3.H12INVIVO.1.P.C_jaspar_format.txt
MEME format	PO3F3.H12INVIVO.1.P.C_meme_format.meme
Transfac format	PO3F3.H12INVIVO.1.P.C_transfac_format.txt
Homer format	PO3F3.H12INVIVO.1.P.C_homer_format_0.001.txt PO3F3.H12INVIVO.1.P.C_homer_format_0.0005.txt PO3F3.H12INVIVO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	145.0	457.0	249.0	147.0
02	409.0	153.0	75.0	361.0
03	48.0	442.0	89.0	419.0
04	471.0	129.0	33.0	365.0
05	89.0	9.0	44.0	856.0
06	34.0	33.0	922.0	9.0
07	382.0	603.0	6.0	7.0
08	970.0	14.0	3.0	11.0
09	43.0	10.0	15.0	930.0
10	670.0	54.0	96.0	178.0
11	301.0	131.0	30.0	536.0
12	122.0	117.0	156.0	603.0
13	268.0	341.0	148.0	241.0
14	680.0	217.0	33.0	68.0
15	353.0	29.0	87.0	529.0
16	120.0	106.0	455.0	317.0
17	389.0	185.0	268.0	156.0
18	368.0	224.0	303.0	103.0

PFM

	A	C	G	T
01	0.145	0.458	0.249	0.147
02	0.41	0.153	0.075	0.362
03	0.048	0.443	0.089	0.42
04	0.472	0.129	0.033	0.366
05	0.089	0.009	0.044	0.858
06	0.034	0.033	0.924	0.009
07	0.383	0.604	0.006	0.007
08	0.972	0.014	0.003	0.011
09	0.043	0.01	0.015	0.932
10	0.671	0.054	0.096	0.178
11	0.302	0.131	0.03	0.537
12	0.122	0.117	0.156	0.604
13	0.269	0.342	0.148	0.241
14	0.681	0.217	0.033	0.068
15	0.354	0.029	0.087	0.53
16	0.12	0.106	0.456	0.318
17	0.39	0.185	0.269	0.156
18	0.369	0.224	0.304	0.103

PWM

	A	C	G	T
01	-0.538	0.602	-0.002	-0.524
02	0.492	-0.485	-1.186	0.367
03	-1.62	0.569	-1.019	0.516
04	0.632	-0.653	-1.979	0.378
05	-1.019	-3.154	-1.704	1.228
06	-1.95	-1.979	1.302	-3.154
07	0.424	0.878	-3.482	-3.36
08	1.353	-2.771	-3.973	-2.983
09	-1.726	-3.065	-2.709	1.311
10	0.983	-1.506	-0.944	-0.335
11	0.186	-0.638	-2.069	0.761
12	-0.708	-0.75	-0.465	0.878
13	0.071	0.311	-0.518	-0.034
14	0.998	-0.139	-1.979	-1.282
15	0.345	-2.101	-1.041	0.748
16	-0.725	-0.847	0.598	0.238
17	0.442	-0.297	0.071	-0.465
18	0.386	-0.107	0.193	-0.875

Standard thresholds

P-value	Threshold
0.001	4.35311
0.0005	5.28036
0.0001	7.18971