PO3F2.H12RSNP.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F2.H12RSNP.0.P.D
Gene (human)	POU3F2 (GeneCards)
Gene synonyms (human)	BRN2, OCT7, OTF7
Gene (mouse)	Pou3f2
Gene synonyms (mouse)	Brn-2, Brn2, Otf7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	16
Consensus	bWCATGAATAWKSAWd
GC content	32.05%
Information content (bits; total / per base)	17.856 / 1.116
Data sources	ChIP-Seq
Aligned words	563

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (15)	0.674	0.732	0.66	0.729	0.608	0.672	3.341	3.912	170.569	264.538
Mouse	8 (51)	0.805	0.938	0.776	0.925	0.771	0.93	4.417	6.421	333.032	500.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.847	0.815	0.766	0.739	0.698	0.68
Overall, 4 experiments	best	0.928	0.902	0.872	0.835	0.808	0.77
Methyl HT-SELEX, 1 experiments	median	0.928	0.902	0.872	0.835	0.808	0.77
Methyl HT-SELEX, 1 experiments	best	0.928	0.902	0.872	0.835	0.808	0.77
Non-Methyl HT-SELEX, 3 experiments	median	0.772	0.742	0.664	0.65	0.591	0.594
Non-Methyl HT-SELEX, 3 experiments	best	0.921	0.889	0.869	0.827	0.806	0.766

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.2
HGNC	HGNC:9215
MGI	MGI:101895
EntrezGene (human)	GeneID:5454 (SSTAR profile)
EntrezGene (mouse)	GeneID:18992 (SSTAR profile)
UniProt ID (human)	PO3F2_HUMAN
UniProt ID (mouse)	PO3F2_MOUSE
UniProt AC (human)	P20265 (TFClass)
UniProt AC (mouse)	P31360 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 8 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	PO3F2.H12RSNP.0.P.D.pcm
PWM	PO3F2.H12RSNP.0.P.D.pwm
PFM	PO3F2.H12RSNP.0.P.D.pfm
Alignment	PO3F2.H12RSNP.0.P.D.words.tsv
Threshold to P-value map	PO3F2.H12RSNP.0.P.D.thr
Motif in other formats
JASPAR format	PO3F2.H12RSNP.0.P.D_jaspar_format.txt
MEME format	PO3F2.H12RSNP.0.P.D_meme_format.meme
Transfac format	PO3F2.H12RSNP.0.P.D_transfac_format.txt
Homer format	PO3F2.H12RSNP.0.P.D_homer_format_0.001.txt PO3F2.H12RSNP.0.P.D_homer_format_0.0005.txt PO3F2.H12RSNP.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	23.0	306.0	138.0	96.0
02	111.0	81.0	26.0	345.0
03	16.0	457.0	27.0	63.0
04	499.0	32.0	6.0	26.0
05	1.0	1.0	8.0	553.0
06	11.0	3.0	549.0	0.0
07	359.0	202.0	0.0	2.0
08	558.0	4.0	0.0	1.0
09	0.0	0.0	1.0	562.0
10	523.0	3.0	13.0	24.0
11	156.0	35.0	1.0	371.0
12	37.0	3.0	105.0	418.0
13	12.0	334.0	147.0	70.0
14	423.0	131.0	4.0	5.0
15	195.0	4.0	24.0	340.0
16	139.0	24.0	218.0	182.0

PFM

	A	C	G	T
01	0.041	0.544	0.245	0.171
02	0.197	0.144	0.046	0.613
03	0.028	0.812	0.048	0.112
04	0.886	0.057	0.011	0.046
05	0.002	0.002	0.014	0.982
06	0.02	0.005	0.975	0.0
07	0.638	0.359	0.0	0.004
08	0.991	0.007	0.0	0.002
09	0.0	0.0	0.002	0.998
10	0.929	0.005	0.023	0.043
11	0.277	0.062	0.002	0.659
12	0.066	0.005	0.187	0.742
13	0.021	0.593	0.261	0.124
14	0.751	0.233	0.007	0.009
15	0.346	0.007	0.043	0.604
16	0.247	0.043	0.387	0.323

PWM

	A	C	G	T
01	-1.756	0.771	-0.02	-0.377
02	-0.234	-0.544	-1.641	0.89
03	-2.091	1.17	-1.605	-0.79
04	1.258	-1.444	-2.932	-1.641
05	-4.009	-4.009	-2.698	1.36
06	-2.426	-3.436	1.353	-4.499
07	0.93	0.358	-4.499	-3.682
08	1.369	-3.238	-4.499	-4.009
09	-4.499	-4.499	-4.009	1.376
10	1.304	-3.436	-2.278	-1.716
11	0.102	-1.359	-4.009	0.962
12	-1.305	-3.436	-0.289	1.081
13	-2.349	0.858	0.043	-0.687
14	1.093	-0.071	-3.238	-3.074
15	0.323	-3.238	-1.716	0.875
16	-0.012	-1.716	0.434	0.254

Standard thresholds

P-value	Threshold
0.001	1.33446
0.0005	2.71801
0.0001	5.61601