PO3F2.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F2.H12INVITRO.0.P.B
Gene (human)	POU3F2 (GeneCards)
Gene synonyms (human)	BRN2, OCT7, OTF7
Gene (mouse)	Pou3f2
Gene synonyms (mouse)	Brn-2, Brn2, Otf7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	hhYATGMATATKYAW
GC content	29.22%
Information content (bits; total / per base)	14.797 / 0.986
Data sources	ChIP-Seq
Aligned words	966

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (15)	0.652	0.725	0.618	0.697	0.612	0.69	3.221	3.798	124.377	214.796
Mouse	8 (51)	0.778	0.929	0.722	0.914	0.751	0.939	4.213	6.856	281.959	459.041

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.859	0.827	0.777	0.75	0.707	0.69
Overall, 4 experiments	best	0.941	0.916	0.895	0.858	0.834	0.796
Methyl HT-SELEX, 1 experiments	median	0.941	0.916	0.895	0.858	0.834	0.796
Methyl HT-SELEX, 1 experiments	best	0.941	0.916	0.895	0.858	0.834	0.796
Non-Methyl HT-SELEX, 3 experiments	median	0.79	0.758	0.671	0.66	0.591	0.598
Non-Methyl HT-SELEX, 3 experiments	best	0.928	0.895	0.882	0.84	0.822	0.781

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.2
HGNC	HGNC:9215
MGI	MGI:101895
EntrezGene (human)	GeneID:5454 (SSTAR profile)
EntrezGene (mouse)	GeneID:18992 (SSTAR profile)
UniProt ID (human)	PO3F2_HUMAN
UniProt ID (mouse)	PO3F2_MOUSE
UniProt AC (human)	P20265 (TFClass)
UniProt AC (mouse)	P31360 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 8 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	PO3F2.H12INVITRO.0.P.B.pcm
PWM	PO3F2.H12INVITRO.0.P.B.pwm
PFM	PO3F2.H12INVITRO.0.P.B.pfm
Alignment	PO3F2.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	PO3F2.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	PO3F2.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	PO3F2.H12INVITRO.0.P.B_meme_format.meme
Transfac format	PO3F2.H12INVITRO.0.P.B_transfac_format.txt
Homer format	PO3F2.H12INVITRO.0.P.B_homer_format_0.001.txt PO3F2.H12INVITRO.0.P.B_homer_format_0.0005.txt PO3F2.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	118.0	437.0	86.0	325.0
02	329.0	99.0	78.0	460.0
03	104.0	637.0	12.0	213.0
04	883.0	48.0	10.0	25.0
05	9.0	2.0	9.0	946.0
06	83.0	8.0	852.0	23.0
07	434.0	506.0	6.0	20.0
08	924.0	24.0	8.0	10.0
09	72.0	10.0	20.0	864.0
10	869.0	26.0	4.0	67.0
11	222.0	13.0	8.0	723.0
12	136.0	9.0	385.0	436.0
13	53.0	527.0	110.0	276.0
14	756.0	163.0	28.0	19.0
15	326.0	54.0	55.0	531.0

PFM

	A	C	G	T
01	0.122	0.452	0.089	0.336
02	0.341	0.102	0.081	0.476
03	0.108	0.659	0.012	0.22
04	0.914	0.05	0.01	0.026
05	0.009	0.002	0.009	0.979
06	0.086	0.008	0.882	0.024
07	0.449	0.524	0.006	0.021
08	0.957	0.025	0.008	0.01
09	0.075	0.01	0.021	0.894
10	0.9	0.027	0.004	0.069
11	0.23	0.013	0.008	0.748
12	0.141	0.009	0.399	0.451
13	0.055	0.546	0.114	0.286
14	0.783	0.169	0.029	0.02
15	0.337	0.056	0.057	0.55

PWM

	A	C	G	T
01	-0.709	0.59	-1.02	0.295
02	0.307	-0.882	-1.115	0.641
03	-0.833	0.966	-2.875	-0.125
04	1.291	-1.588	-3.033	-2.209
05	-3.122	-4.181	-3.122	1.36
06	-1.055	-3.22	1.256	-2.286
07	0.583	0.736	-3.45	-2.416
08	1.337	-2.247	-3.22	-3.033
09	-1.194	-3.033	-2.416	1.27
10	1.275	-2.172	-3.75	-1.264
11	-0.084	-2.805	-3.22	1.092
12	-0.569	-3.122	0.464	0.588
13	-1.492	0.776	-0.778	0.133
14	1.136	-0.39	-2.102	-2.463
15	0.298	-1.474	-1.456	0.784

Standard thresholds

P-value	Threshold
0.001	3.11131
0.0005	4.24786
0.0001	6.62386