MotifPO3F2.H12CORE.2.SM.B
Gene (human)POU3F2
(GeneCards)
Gene synonyms (human)BRN2, OCT7, OTF7
Gene (mouse)Pou3f2
Gene synonyms (mouse)Brn-2, Brn2, Otf7
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length16
ConsensusnvCTMATTAGCATAMh
GC content33.68%
Information content (bits; total / per base)18.185 / 1.137
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words5430

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (15) 0.478 0.5 0.323 0.332 0.415 0.444 0.853 0.943 0.131 0.959
Mouse 8 (51) 0.637 0.704 0.469 0.545 0.582 0.653 1.599 1.935 11.585 40.959

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.904 0.894 0.834 0.827 0.771 0.767
best 0.999 0.999 0.99 0.987 0.944 0.936
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.99 0.987 0.944 0.936
best 0.999 0.999 0.99 0.987 0.944 0.936
Non-Methyl HT-SELEX, 3 experiments median 0.813 0.796 0.688 0.682 0.608 0.614
best 0.995 0.992 0.979 0.972 0.933 0.92
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.2
HGNCHGNC:9215
MGIMGI:101895
EntrezGene (human)GeneID:5454
(SSTAR profile)
EntrezGene (mouse)GeneID:18992
(SSTAR profile)
UniProt ID (human)PO3F2_HUMAN
UniProt ID (mouse)PO3F2_MOUSE
UniProt AC (human)P20265
(TFClass)
UniProt AC (mouse)P31360
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 8 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011928.51507.51084.5909.5
02835.52738.51160.5695.5
03197.04382.0363.0488.0
04106.087.090.05147.0
052604.02787.036.03.0
065427.02.01.00.0
070.01.00.05429.0
085.04.08.05413.0
094253.08.00.01169.0
10515.0301.04458.0156.0
119.05121.0176.0124.0
124918.0216.0198.098.0
13101.0274.076.04979.0
144431.0213.0448.0338.0
153212.01044.0270.0904.0
161016.751229.75977.752205.75
PFM
ACGT
010.3550.2780.20.167
020.1540.5040.2140.128
030.0360.8070.0670.09
040.020.0160.0170.948
050.480.5130.0070.001
060.9990.00.00.0
070.00.00.01.0
080.0010.0010.0010.997
090.7830.0010.00.215
100.0950.0550.8210.029
110.0020.9430.0320.023
120.9060.040.0360.018
130.0190.050.0140.917
140.8160.0390.0830.062
150.5920.1920.050.166
160.1870.2260.180.406
PWM
ACGT
010.3510.105-0.224-0.4
02-0.4840.701-0.157-0.667
03-1.9211.171-1.315-1.02
04-2.531-2.725-2.6921.332
050.6510.719-3.573-5.576
061.385-5.792-6.068-6.45
07-6.45-6.068-6.451.385
08-5.248-5.399-4.8981.382
091.141-4.898-6.45-0.149
10-0.967-1.5011.188-2.151
11-4.8041.327-2.032-2.378
121.286-1.83-1.916-2.608
13-2.579-1.594-2.8561.298
141.182-1.844-1.105-1.386
150.86-0.262-1.609-0.406
16-0.289-0.099-0.3280.485
Standard thresholds
P-value Threshold
0.001 0.27976
0.0005 1.86406
0.0001 5.12986