Motif | PO3F2.H12CORE.2.SM.B |
Gene (human) | POU3F2 (GeneCards) |
Gene synonyms (human) | BRN2, OCT7, OTF7 |
Gene (mouse) | Pou3f2 |
Gene synonyms (mouse) | Brn-2, Brn2, Otf7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif | PO3F2.H12CORE.2.SM.B |
Gene (human) | POU3F2 (GeneCards) |
Gene synonyms (human) | BRN2, OCT7, OTF7 |
Gene (mouse) | Pou3f2 |
Gene synonyms (mouse) | Brn-2, Brn2, Otf7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif length | 16 |
Consensus | nvCTMATTAGCATAMh |
GC content | 33.68% |
Information content (bits; total / per base) | 18.185 / 1.137 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 5430 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 3 (15) | 0.478 | 0.5 | 0.323 | 0.332 | 0.415 | 0.444 | 0.853 | 0.943 | 0.131 | 0.959 |
Mouse | 8 (51) | 0.637 | 0.704 | 0.469 | 0.545 | 0.582 | 0.653 | 1.599 | 1.935 | 11.585 | 40.959 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.904 | 0.894 | 0.834 | 0.827 | 0.771 | 0.767 |
best | 0.999 | 0.999 | 0.99 | 0.987 | 0.944 | 0.936 | |
Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.99 | 0.987 | 0.944 | 0.936 |
best | 0.999 | 0.999 | 0.99 | 0.987 | 0.944 | 0.936 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.813 | 0.796 | 0.688 | 0.682 | 0.608 | 0.614 |
best | 0.995 | 0.992 | 0.979 | 0.972 | 0.933 | 0.92 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU3 {3.1.10.3} (TFClass) |
TFClass ID | TFClass: 3.1.10.3.2 |
HGNC | HGNC:9215 |
MGI | MGI:101895 |
EntrezGene (human) | GeneID:5454 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18992 (SSTAR profile) |
UniProt ID (human) | PO3F2_HUMAN |
UniProt ID (mouse) | PO3F2_MOUSE |
UniProt AC (human) | P20265 (TFClass) |
UniProt AC (mouse) | P31360 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 3 human, 8 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | PO3F2.H12CORE.2.SM.B.pcm |
PWM | PO3F2.H12CORE.2.SM.B.pwm |
PFM | PO3F2.H12CORE.2.SM.B.pfm |
Alignment | PO3F2.H12CORE.2.SM.B.words.tsv |
Threshold to P-value map | PO3F2.H12CORE.2.SM.B.thr |
Motif in other formats | |
JASPAR format | PO3F2.H12CORE.2.SM.B_jaspar_format.txt |
MEME format | PO3F2.H12CORE.2.SM.B_meme_format.meme |
Transfac format | PO3F2.H12CORE.2.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1928.5 | 1507.5 | 1084.5 | 909.5 |
02 | 835.5 | 2738.5 | 1160.5 | 695.5 |
03 | 197.0 | 4382.0 | 363.0 | 488.0 |
04 | 106.0 | 87.0 | 90.0 | 5147.0 |
05 | 2604.0 | 2787.0 | 36.0 | 3.0 |
06 | 5427.0 | 2.0 | 1.0 | 0.0 |
07 | 0.0 | 1.0 | 0.0 | 5429.0 |
08 | 5.0 | 4.0 | 8.0 | 5413.0 |
09 | 4253.0 | 8.0 | 0.0 | 1169.0 |
10 | 515.0 | 301.0 | 4458.0 | 156.0 |
11 | 9.0 | 5121.0 | 176.0 | 124.0 |
12 | 4918.0 | 216.0 | 198.0 | 98.0 |
13 | 101.0 | 274.0 | 76.0 | 4979.0 |
14 | 4431.0 | 213.0 | 448.0 | 338.0 |
15 | 3212.0 | 1044.0 | 270.0 | 904.0 |
16 | 1016.75 | 1229.75 | 977.75 | 2205.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.355 | 0.278 | 0.2 | 0.167 |
02 | 0.154 | 0.504 | 0.214 | 0.128 |
03 | 0.036 | 0.807 | 0.067 | 0.09 |
04 | 0.02 | 0.016 | 0.017 | 0.948 |
05 | 0.48 | 0.513 | 0.007 | 0.001 |
06 | 0.999 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 0.001 | 0.001 | 0.001 | 0.997 |
09 | 0.783 | 0.001 | 0.0 | 0.215 |
10 | 0.095 | 0.055 | 0.821 | 0.029 |
11 | 0.002 | 0.943 | 0.032 | 0.023 |
12 | 0.906 | 0.04 | 0.036 | 0.018 |
13 | 0.019 | 0.05 | 0.014 | 0.917 |
14 | 0.816 | 0.039 | 0.083 | 0.062 |
15 | 0.592 | 0.192 | 0.05 | 0.166 |
16 | 0.187 | 0.226 | 0.18 | 0.406 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.351 | 0.105 | -0.224 | -0.4 |
02 | -0.484 | 0.701 | -0.157 | -0.667 |
03 | -1.921 | 1.171 | -1.315 | -1.02 |
04 | -2.531 | -2.725 | -2.692 | 1.332 |
05 | 0.651 | 0.719 | -3.573 | -5.576 |
06 | 1.385 | -5.792 | -6.068 | -6.45 |
07 | -6.45 | -6.068 | -6.45 | 1.385 |
08 | -5.248 | -5.399 | -4.898 | 1.382 |
09 | 1.141 | -4.898 | -6.45 | -0.149 |
10 | -0.967 | -1.501 | 1.188 | -2.151 |
11 | -4.804 | 1.327 | -2.032 | -2.378 |
12 | 1.286 | -1.83 | -1.916 | -2.608 |
13 | -2.579 | -1.594 | -2.856 | 1.298 |
14 | 1.182 | -1.844 | -1.105 | -1.386 |
15 | 0.86 | -0.262 | -1.609 | -0.406 |
16 | -0.289 | -0.099 | -0.328 | 0.485 |
P-value | Threshold |
---|---|
0.001 | 0.27976 |
0.0005 | 1.86406 |
0.0001 | 5.12986 |