MotifPO3F2.H12CORE.1.S.B
Gene (human)POU3F2
(GeneCards)
Gene synonyms (human)BRN2, OCT7, OTF7
Gene (mouse)Pou3f2
Gene synonyms (mouse)Brn-2, Brn2, Otf7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length15
ConsensusndhRYTAATTAdbhd
GC content28.13%
Information content (bits; total / per base)12.407 / 0.827
Data sourcesHT-SELEX
Aligned words665

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (15) 0.551 0.572 0.395 0.412 0.441 0.487 1.029 1.177 27.886 51.959
Mouse 8 (51) 0.661 0.735 0.468 0.551 0.574 0.691 1.45 1.94 50.301 106.658

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.881 0.847 0.818 0.79 0.76 0.74
best 0.975 0.958 0.962 0.94 0.935 0.908
Methyl HT-SELEX, 1 experiments median 0.975 0.958 0.962 0.94 0.935 0.908
best 0.975 0.958 0.962 0.94 0.935 0.908
Non-Methyl HT-SELEX, 3 experiments median 0.803 0.76 0.695 0.671 0.614 0.611
best 0.96 0.934 0.94 0.908 0.906 0.869
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.2
HGNCHGNC:9215
MGIMGI:101895
EntrezGene (human)GeneID:5454
(SSTAR profile)
EntrezGene (mouse)GeneID:18992
(SSTAR profile)
UniProt ID (human)PO3F2_HUMAN
UniProt ID (mouse)PO3F2_MOUSE
UniProt AC (human)P20265
(TFClass)
UniProt AC (mouse)P31360
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 8 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01147.25148.25151.25218.25
02158.7566.75284.75154.75
03260.0214.072.0119.0
04387.059.0167.052.0
0510.0134.050.0471.0
0676.00.075.0514.0
07587.076.01.01.0
08664.00.01.00.0
090.00.00.0665.0
100.00.032.0633.0
11661.01.03.00.0
12157.071.0179.0258.0
1341.0228.0282.0114.0
14192.5266.573.5132.5
15276.083.087.0219.0
PFM
ACGT
010.2210.2230.2270.328
020.2390.10.4280.233
030.3910.3220.1080.179
040.5820.0890.2510.078
050.0150.2020.0750.708
060.1140.00.1130.773
070.8830.1140.0020.002
080.9980.00.0020.0
090.00.00.01.0
100.00.00.0480.952
110.9940.0020.0050.0
120.2360.1070.2690.388
130.0620.3430.4240.171
140.2890.4010.1110.199
150.4150.1250.1310.329
PWM
ACGT
01-0.12-0.113-0.0940.27
02-0.046-0.8980.534-0.071
030.4440.25-0.824-0.331
040.839-1.0190.004-1.141
05-2.67-0.213-1.1791.035
06-0.771-4.638-0.7841.122
071.255-0.771-4.158-4.158
081.378-4.638-4.158-4.638
09-4.638-4.638-4.6381.379
10-4.638-4.638-1.6081.33
111.373-4.158-3.592-4.638
12-0.057-0.8380.0730.436
13-1.3710.3130.524-0.373
140.1450.468-0.804-0.224
150.503-0.685-0.6390.273
Standard thresholds
P-value Threshold
0.001 3.83191
0.0005 5.07841
0.0001 7.40756