Motif | PO3F2.H12CORE.1.S.B |
Gene (human) | POU3F2 (GeneCards) |
Gene synonyms (human) | BRN2, OCT7, OTF7 |
Gene (mouse) | Pou3f2 |
Gene synonyms (mouse) | Brn-2, Brn2, Otf7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | PO3F2.H12CORE.1.S.B |
Gene (human) | POU3F2 (GeneCards) |
Gene synonyms (human) | BRN2, OCT7, OTF7 |
Gene (mouse) | Pou3f2 |
Gene synonyms (mouse) | Brn-2, Brn2, Otf7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 15 |
Consensus | ndhRYTAATTAdbhd |
GC content | 28.13% |
Information content (bits; total / per base) | 12.407 / 0.827 |
Data sources | HT-SELEX |
Aligned words | 665 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 3 (15) | 0.551 | 0.572 | 0.395 | 0.412 | 0.441 | 0.487 | 1.029 | 1.177 | 27.886 | 51.959 |
Mouse | 8 (51) | 0.661 | 0.735 | 0.468 | 0.551 | 0.574 | 0.691 | 1.45 | 1.94 | 50.301 | 106.658 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.881 | 0.847 | 0.818 | 0.79 | 0.76 | 0.74 |
best | 0.975 | 0.958 | 0.962 | 0.94 | 0.935 | 0.908 | |
Methyl HT-SELEX, 1 experiments | median | 0.975 | 0.958 | 0.962 | 0.94 | 0.935 | 0.908 |
best | 0.975 | 0.958 | 0.962 | 0.94 | 0.935 | 0.908 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.803 | 0.76 | 0.695 | 0.671 | 0.614 | 0.611 |
best | 0.96 | 0.934 | 0.94 | 0.908 | 0.906 | 0.869 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU3 {3.1.10.3} (TFClass) |
TFClass ID | TFClass: 3.1.10.3.2 |
HGNC | HGNC:9215 |
MGI | MGI:101895 |
EntrezGene (human) | GeneID:5454 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18992 (SSTAR profile) |
UniProt ID (human) | PO3F2_HUMAN |
UniProt ID (mouse) | PO3F2_MOUSE |
UniProt AC (human) | P20265 (TFClass) |
UniProt AC (mouse) | P31360 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 3 human, 8 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | PO3F2.H12CORE.1.S.B.pcm |
PWM | PO3F2.H12CORE.1.S.B.pwm |
PFM | PO3F2.H12CORE.1.S.B.pfm |
Alignment | PO3F2.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | PO3F2.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | PO3F2.H12CORE.1.S.B_jaspar_format.txt |
MEME format | PO3F2.H12CORE.1.S.B_meme_format.meme |
Transfac format | PO3F2.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 147.25 | 148.25 | 151.25 | 218.25 |
02 | 158.75 | 66.75 | 284.75 | 154.75 |
03 | 260.0 | 214.0 | 72.0 | 119.0 |
04 | 387.0 | 59.0 | 167.0 | 52.0 |
05 | 10.0 | 134.0 | 50.0 | 471.0 |
06 | 76.0 | 0.0 | 75.0 | 514.0 |
07 | 587.0 | 76.0 | 1.0 | 1.0 |
08 | 664.0 | 0.0 | 1.0 | 0.0 |
09 | 0.0 | 0.0 | 0.0 | 665.0 |
10 | 0.0 | 0.0 | 32.0 | 633.0 |
11 | 661.0 | 1.0 | 3.0 | 0.0 |
12 | 157.0 | 71.0 | 179.0 | 258.0 |
13 | 41.0 | 228.0 | 282.0 | 114.0 |
14 | 192.5 | 266.5 | 73.5 | 132.5 |
15 | 276.0 | 83.0 | 87.0 | 219.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.221 | 0.223 | 0.227 | 0.328 |
02 | 0.239 | 0.1 | 0.428 | 0.233 |
03 | 0.391 | 0.322 | 0.108 | 0.179 |
04 | 0.582 | 0.089 | 0.251 | 0.078 |
05 | 0.015 | 0.202 | 0.075 | 0.708 |
06 | 0.114 | 0.0 | 0.113 | 0.773 |
07 | 0.883 | 0.114 | 0.002 | 0.002 |
08 | 0.998 | 0.0 | 0.002 | 0.0 |
09 | 0.0 | 0.0 | 0.0 | 1.0 |
10 | 0.0 | 0.0 | 0.048 | 0.952 |
11 | 0.994 | 0.002 | 0.005 | 0.0 |
12 | 0.236 | 0.107 | 0.269 | 0.388 |
13 | 0.062 | 0.343 | 0.424 | 0.171 |
14 | 0.289 | 0.401 | 0.111 | 0.199 |
15 | 0.415 | 0.125 | 0.131 | 0.329 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.12 | -0.113 | -0.094 | 0.27 |
02 | -0.046 | -0.898 | 0.534 | -0.071 |
03 | 0.444 | 0.25 | -0.824 | -0.331 |
04 | 0.839 | -1.019 | 0.004 | -1.141 |
05 | -2.67 | -0.213 | -1.179 | 1.035 |
06 | -0.771 | -4.638 | -0.784 | 1.122 |
07 | 1.255 | -0.771 | -4.158 | -4.158 |
08 | 1.378 | -4.638 | -4.158 | -4.638 |
09 | -4.638 | -4.638 | -4.638 | 1.379 |
10 | -4.638 | -4.638 | -1.608 | 1.33 |
11 | 1.373 | -4.158 | -3.592 | -4.638 |
12 | -0.057 | -0.838 | 0.073 | 0.436 |
13 | -1.371 | 0.313 | 0.524 | -0.373 |
14 | 0.145 | 0.468 | -0.804 | -0.224 |
15 | 0.503 | -0.685 | -0.639 | 0.273 |
P-value | Threshold |
---|---|
0.001 | 3.83191 |
0.0005 | 5.07841 |
0.0001 | 7.40756 |