Motif | PO3F2.H12CORE.0.P.B |
Gene (human) | POU3F2 (GeneCards) |
Gene synonyms (human) | BRN2, OCT7, OTF7 |
Gene (mouse) | Pou3f2 |
Gene synonyms (mouse) | Brn-2, Brn2, Otf7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | PO3F2.H12CORE.0.P.B |
Gene (human) | POU3F2 (GeneCards) |
Gene synonyms (human) | BRN2, OCT7, OTF7 |
Gene (mouse) | Pou3f2 |
Gene synonyms (mouse) | Brn-2, Brn2, Otf7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 16 |
Consensus | bWCATGAATAWKSAWd |
GC content | 32.05% |
Information content (bits; total / per base) | 17.856 / 1.116 |
Data sources | ChIP-Seq |
Aligned words | 563 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 3 (15) | 0.674 | 0.732 | 0.66 | 0.729 | 0.608 | 0.672 | 3.341 | 3.912 | 170.569 | 264.538 |
Mouse | 8 (51) | 0.805 | 0.938 | 0.776 | 0.925 | 0.771 | 0.93 | 4.417 | 6.421 | 333.032 | 500.886 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.847 | 0.815 | 0.766 | 0.739 | 0.698 | 0.68 |
best | 0.928 | 0.902 | 0.872 | 0.835 | 0.808 | 0.77 | |
Methyl HT-SELEX, 1 experiments | median | 0.928 | 0.902 | 0.872 | 0.835 | 0.808 | 0.77 |
best | 0.928 | 0.902 | 0.872 | 0.835 | 0.808 | 0.77 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.772 | 0.742 | 0.664 | 0.65 | 0.591 | 0.594 |
best | 0.921 | 0.889 | 0.869 | 0.827 | 0.806 | 0.766 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | POU3 {3.1.10.3} (TFClass) |
TFClass ID | TFClass: 3.1.10.3.2 |
HGNC | HGNC:9215 |
MGI | MGI:101895 |
EntrezGene (human) | GeneID:5454 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18992 (SSTAR profile) |
UniProt ID (human) | PO3F2_HUMAN |
UniProt ID (mouse) | PO3F2_MOUSE |
UniProt AC (human) | P20265 (TFClass) |
UniProt AC (mouse) | P31360 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 3 human, 8 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | PO3F2.H12CORE.0.P.B.pcm |
PWM | PO3F2.H12CORE.0.P.B.pwm |
PFM | PO3F2.H12CORE.0.P.B.pfm |
Alignment | PO3F2.H12CORE.0.P.B.words.tsv |
Threshold to P-value map | PO3F2.H12CORE.0.P.B.thr |
Motif in other formats | |
JASPAR format | PO3F2.H12CORE.0.P.B_jaspar_format.txt |
MEME format | PO3F2.H12CORE.0.P.B_meme_format.meme |
Transfac format | PO3F2.H12CORE.0.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 23.0 | 306.0 | 138.0 | 96.0 |
02 | 111.0 | 81.0 | 26.0 | 345.0 |
03 | 16.0 | 457.0 | 27.0 | 63.0 |
04 | 499.0 | 32.0 | 6.0 | 26.0 |
05 | 1.0 | 1.0 | 8.0 | 553.0 |
06 | 11.0 | 3.0 | 549.0 | 0.0 |
07 | 359.0 | 202.0 | 0.0 | 2.0 |
08 | 558.0 | 4.0 | 0.0 | 1.0 |
09 | 0.0 | 0.0 | 1.0 | 562.0 |
10 | 523.0 | 3.0 | 13.0 | 24.0 |
11 | 156.0 | 35.0 | 1.0 | 371.0 |
12 | 37.0 | 3.0 | 105.0 | 418.0 |
13 | 12.0 | 334.0 | 147.0 | 70.0 |
14 | 423.0 | 131.0 | 4.0 | 5.0 |
15 | 195.0 | 4.0 | 24.0 | 340.0 |
16 | 139.0 | 24.0 | 218.0 | 182.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.041 | 0.544 | 0.245 | 0.171 |
02 | 0.197 | 0.144 | 0.046 | 0.613 |
03 | 0.028 | 0.812 | 0.048 | 0.112 |
04 | 0.886 | 0.057 | 0.011 | 0.046 |
05 | 0.002 | 0.002 | 0.014 | 0.982 |
06 | 0.02 | 0.005 | 0.975 | 0.0 |
07 | 0.638 | 0.359 | 0.0 | 0.004 |
08 | 0.991 | 0.007 | 0.0 | 0.002 |
09 | 0.0 | 0.0 | 0.002 | 0.998 |
10 | 0.929 | 0.005 | 0.023 | 0.043 |
11 | 0.277 | 0.062 | 0.002 | 0.659 |
12 | 0.066 | 0.005 | 0.187 | 0.742 |
13 | 0.021 | 0.593 | 0.261 | 0.124 |
14 | 0.751 | 0.233 | 0.007 | 0.009 |
15 | 0.346 | 0.007 | 0.043 | 0.604 |
16 | 0.247 | 0.043 | 0.387 | 0.323 |
A | C | G | T | |
---|---|---|---|---|
01 | -1.756 | 0.771 | -0.02 | -0.377 |
02 | -0.234 | -0.544 | -1.641 | 0.89 |
03 | -2.091 | 1.17 | -1.605 | -0.79 |
04 | 1.258 | -1.444 | -2.932 | -1.641 |
05 | -4.009 | -4.009 | -2.698 | 1.36 |
06 | -2.426 | -3.436 | 1.353 | -4.499 |
07 | 0.93 | 0.358 | -4.499 | -3.682 |
08 | 1.369 | -3.238 | -4.499 | -4.009 |
09 | -4.499 | -4.499 | -4.009 | 1.376 |
10 | 1.304 | -3.436 | -2.278 | -1.716 |
11 | 0.102 | -1.359 | -4.009 | 0.962 |
12 | -1.305 | -3.436 | -0.289 | 1.081 |
13 | -2.349 | 0.858 | 0.043 | -0.687 |
14 | 1.093 | -0.071 | -3.238 | -3.074 |
15 | 0.323 | -3.238 | -1.716 | 0.875 |
16 | -0.012 | -1.716 | 0.434 | 0.254 |
P-value | Threshold |
---|---|
0.001 | 1.33446 |
0.0005 | 2.71801 |
0.0001 | 5.61601 |