MotifPO3F2.H12CORE.0.P.B
Gene (human)POU3F2
(GeneCards)
Gene synonyms (human)BRN2, OCT7, OTF7
Gene (mouse)Pou3f2
Gene synonyms (mouse)Brn-2, Brn2, Otf7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusbWCATGAATAWKSAWd
GC content32.05%
Information content (bits; total / per base)17.856 / 1.116
Data sourcesChIP-Seq
Aligned words563

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (15) 0.674 0.732 0.66 0.729 0.608 0.672 3.341 3.912 170.569 264.538
Mouse 8 (51) 0.805 0.938 0.776 0.925 0.771 0.93 4.417 6.421 333.032 500.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.847 0.815 0.766 0.739 0.698 0.68
best 0.928 0.902 0.872 0.835 0.808 0.77
Methyl HT-SELEX, 1 experiments median 0.928 0.902 0.872 0.835 0.808 0.77
best 0.928 0.902 0.872 0.835 0.808 0.77
Non-Methyl HT-SELEX, 3 experiments median 0.772 0.742 0.664 0.65 0.591 0.594
best 0.921 0.889 0.869 0.827 0.806 0.766
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.2
HGNCHGNC:9215
MGIMGI:101895
EntrezGene (human)GeneID:5454
(SSTAR profile)
EntrezGene (mouse)GeneID:18992
(SSTAR profile)
UniProt ID (human)PO3F2_HUMAN
UniProt ID (mouse)PO3F2_MOUSE
UniProt AC (human)P20265
(TFClass)
UniProt AC (mouse)P31360
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 8 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0123.0306.0138.096.0
02111.081.026.0345.0
0316.0457.027.063.0
04499.032.06.026.0
051.01.08.0553.0
0611.03.0549.00.0
07359.0202.00.02.0
08558.04.00.01.0
090.00.01.0562.0
10523.03.013.024.0
11156.035.01.0371.0
1237.03.0105.0418.0
1312.0334.0147.070.0
14423.0131.04.05.0
15195.04.024.0340.0
16139.024.0218.0182.0
PFM
ACGT
010.0410.5440.2450.171
020.1970.1440.0460.613
030.0280.8120.0480.112
040.8860.0570.0110.046
050.0020.0020.0140.982
060.020.0050.9750.0
070.6380.3590.00.004
080.9910.0070.00.002
090.00.00.0020.998
100.9290.0050.0230.043
110.2770.0620.0020.659
120.0660.0050.1870.742
130.0210.5930.2610.124
140.7510.2330.0070.009
150.3460.0070.0430.604
160.2470.0430.3870.323
PWM
ACGT
01-1.7560.771-0.02-0.377
02-0.234-0.544-1.6410.89
03-2.0911.17-1.605-0.79
041.258-1.444-2.932-1.641
05-4.009-4.009-2.6981.36
06-2.426-3.4361.353-4.499
070.930.358-4.499-3.682
081.369-3.238-4.499-4.009
09-4.499-4.499-4.0091.376
101.304-3.436-2.278-1.716
110.102-1.359-4.0090.962
12-1.305-3.436-0.2891.081
13-2.3490.8580.043-0.687
141.093-0.071-3.238-3.074
150.323-3.238-1.7160.875
16-0.012-1.7160.4340.254
Standard thresholds
P-value Threshold
0.001 1.33446
0.0005 2.71801
0.0001 5.61601