PO3F1.H12RSNP.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F1.H12RSNP.0.P.D
Gene (human)	POU3F1 (GeneCards)
Gene synonyms (human)	OCT6, OTF6
Gene (mouse)	Pou3f1
Gene synonyms (mouse)	Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	15
Consensus	dhATGMAWATKhvnn
GC content	33.53%
Information content (bits; total / per base)	10.432 / 0.695
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	6 (39)	0.776	0.875	0.674	0.8	0.743	0.826	2.294	3.095	44.222	166.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.987	0.978	0.96	0.946	0.863	0.857
Overall, 4 experiments	best	0.997	0.995	0.991	0.987	0.958	0.951
Methyl HT-SELEX, 1 experiments	median	0.989	0.98	0.971	0.959	0.909	0.894
Methyl HT-SELEX, 1 experiments	best	0.989	0.98	0.971	0.959	0.909	0.894
Non-Methyl HT-SELEX, 3 experiments	median	0.984	0.976	0.948	0.933	0.818	0.821
Non-Methyl HT-SELEX, 3 experiments	best	0.997	0.995	0.991	0.987	0.958	0.951

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.1
HGNC	HGNC:9214
MGI	MGI:101896
EntrezGene (human)	GeneID:5453 (SSTAR profile)
EntrezGene (mouse)	GeneID:18991 (SSTAR profile)
UniProt ID (human)	PO3F1_HUMAN
UniProt ID (mouse)	PO3F1_MOUSE
UniProt AC (human)	Q03052 (TFClass)
UniProt AC (mouse)	P21952 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 6 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	PO3F1.H12RSNP.0.P.D.pcm
PWM	PO3F1.H12RSNP.0.P.D.pwm
PFM	PO3F1.H12RSNP.0.P.D.pfm
Alignment	PO3F1.H12RSNP.0.P.D.words.tsv
Threshold to P-value map	PO3F1.H12RSNP.0.P.D.thr
Motif in other formats
JASPAR format	PO3F1.H12RSNP.0.P.D_jaspar_format.txt
MEME format	PO3F1.H12RSNP.0.P.D_meme_format.meme
Transfac format	PO3F1.H12RSNP.0.P.D_transfac_format.txt
Homer format	PO3F1.H12RSNP.0.P.D_homer_format_0.001.txt PO3F1.H12RSNP.0.P.D_homer_format_0.0005.txt PO3F1.H12RSNP.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	237.0	100.0	230.0	429.0
02	193.0	466.0	85.0	252.0
03	871.0	64.0	19.0	42.0
04	19.0	2.0	25.0	950.0
05	32.0	33.0	871.0	60.0
06	213.0	612.0	75.0	96.0
07	730.0	20.0	5.0	241.0
08	575.0	11.0	79.0	331.0
09	937.0	24.0	22.0	13.0
10	113.0	16.0	52.0	815.0
11	48.0	45.0	447.0	456.0
12	373.0	284.0	158.0	181.0
13	519.0	157.0	227.0	93.0
14	294.0	154.0	221.0	327.0
15	215.0	203.0	302.0	276.0

PFM

	A	C	G	T
01	0.238	0.1	0.231	0.431
02	0.194	0.468	0.085	0.253
03	0.874	0.064	0.019	0.042
04	0.019	0.002	0.025	0.954
05	0.032	0.033	0.874	0.06
06	0.214	0.614	0.075	0.096
07	0.733	0.02	0.005	0.242
08	0.577	0.011	0.079	0.332
09	0.941	0.024	0.022	0.013
10	0.113	0.016	0.052	0.818
11	0.048	0.045	0.449	0.458
12	0.374	0.285	0.159	0.182
13	0.521	0.158	0.228	0.093
14	0.295	0.155	0.222	0.328
15	0.216	0.204	0.303	0.277

PWM

	A	C	G	T
01	-0.049	-0.902	-0.079	0.541
02	-0.253	0.624	-1.062	0.012
03	1.247	-1.339	-2.493	-1.746
04	-2.493	-4.209	-2.239	1.334
05	-2.006	-1.977	1.247	-1.402
06	-0.155	0.895	-1.184	-0.942
07	1.071	-2.446	-3.618	-0.032
08	0.833	-2.981	-1.133	0.283
09	1.32	-2.277	-2.358	-2.835
10	-0.782	-2.649	-1.54	1.181
11	-1.618	-1.68	0.582	0.602
12	0.402	0.131	-0.451	-0.316
13	0.731	-0.457	-0.092	-0.973
14	0.165	-0.476	-0.118	0.271
15	-0.146	-0.203	0.192	0.102

Standard thresholds

P-value	Threshold
0.001	4.61991
0.0005	5.47916
0.0001	7.24346