MotifPO3F1.H12INVIVO.2.S.C
Gene (human)POU3F1
(GeneCards)
Gene synonyms (human)OCT6, OTF6
Gene (mouse)Pou3f1
Gene synonyms (mouse)Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length9
ConsensusnTAATTMvn
GC content26.55%
Information content (bits; total / per base)9.362 / 1.04
Data sourcesHT-SELEX
Aligned words9399

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.623 0.808 0.444 0.656 0.482 0.725 1.031 1.836 6.201 30.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.95 0.927 0.917 0.886 0.876 0.839
best 0.981 0.97 0.942 0.917 0.912 0.877
Methyl HT-SELEX, 1 experiments median 0.965 0.945 0.942 0.914 0.912 0.877
best 0.965 0.945 0.942 0.914 0.912 0.877
Non-Methyl HT-SELEX, 3 experiments median 0.934 0.909 0.896 0.858 0.855 0.811
best 0.981 0.97 0.938 0.917 0.897 0.867
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.1
HGNCHGNC:9214
MGIMGI:101896
EntrezGene (human)GeneID:5453
(SSTAR profile)
EntrezGene (mouse)GeneID:18991
(SSTAR profile)
UniProt ID (human)PO3F1_HUMAN
UniProt ID (mouse)PO3F1_MOUSE
UniProt AC (human)Q03052
(TFClass)
UniProt AC (mouse)P21952
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012325.51842.52867.52363.5
0214.045.043.09297.0
038687.00.0712.00.0
049368.02.029.00.0
051.0160.0283.08955.0
0623.00.03343.06033.0
077097.01160.0464.0678.0
082862.251463.254406.25667.25
091569.03025.02615.02190.0
PFM
ACGT
010.2470.1960.3050.251
020.0010.0050.0050.989
030.9240.00.0760.0
040.9970.00.0030.0
050.00.0170.030.953
060.0020.00.3560.642
070.7550.1230.0490.072
080.3050.1560.4690.071
090.1670.3220.2780.233
PWM
ACGT
01-0.01-0.2430.1990.006
02-4.973-3.907-3.951.375
031.307-6.936-1.192-6.936
041.382-6.307-4.32-6.936
05-6.573-2.674-2.111.337
06-4.533-6.9360.3520.942
071.105-0.705-1.618-1.241
080.197-0.4730.628-1.256
09-0.4030.2520.107-0.07
Standard thresholds
P-value Threshold
0.001 5.17008
0.0005 5.96333
0.0001 7.63749