PO3F1.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	PO3F1.H12INVIVO.0.P.B
Gene (human)	POU3F1 (GeneCards)
Gene synonyms (human)	OCT6, OTF6
Gene (mouse)	Pou3f1
Gene synonyms (mouse)	Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	hKnvdWATGCAdRdb
GC content	32.49%
Information content (bits; total / per base)	10.313 / 0.688
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	6 (39)	0.799	0.915	0.671	0.842	0.746	0.881	2.327	3.684	73.602	276.398

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.973	0.959	0.94	0.918	0.844	0.83
Overall, 4 experiments	best	0.997	0.995	0.99	0.985	0.961	0.953
Methyl HT-SELEX, 1 experiments	median	0.964	0.944	0.931	0.902	0.862	0.835
Methyl HT-SELEX, 1 experiments	best	0.964	0.944	0.931	0.902	0.862	0.835
Non-Methyl HT-SELEX, 3 experiments	median	0.983	0.974	0.949	0.933	0.825	0.826
Non-Methyl HT-SELEX, 3 experiments	best	0.997	0.995	0.99	0.985	0.961	0.953

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	POU {3.1.10} (TFClass)
TF subfamily	POU3 {3.1.10.3} (TFClass)
TFClass ID	TFClass: 3.1.10.3.1
HGNC	HGNC:9214
MGI	MGI:101896
EntrezGene (human)	GeneID:5453 (SSTAR profile)
EntrezGene (mouse)	GeneID:18991 (SSTAR profile)
UniProt ID (human)	PO3F1_HUMAN
UniProt ID (mouse)	PO3F1_MOUSE
UniProt AC (human)	Q03052 (TFClass)
UniProt AC (mouse)	P21952 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 6 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	PO3F1.H12INVIVO.0.P.B.pcm
PWM	PO3F1.H12INVIVO.0.P.B.pwm
PFM	PO3F1.H12INVIVO.0.P.B.pfm
Alignment	PO3F1.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	PO3F1.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	PO3F1.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	PO3F1.H12INVIVO.0.P.B_meme_format.meme
Transfac format	PO3F1.H12INVIVO.0.P.B_transfac_format.txt
Homer format	PO3F1.H12INVIVO.0.P.B_homer_format_0.001.txt PO3F1.H12INVIVO.0.P.B_homer_format_0.0005.txt PO3F1.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	456.0	127.0	95.0	321.0
02	139.0	52.0	146.0	662.0
03	251.0	142.0	312.0	294.0
04	537.0	165.0	162.0	135.0
05	487.0	67.0	114.0	331.0
06	212.0	136.0	59.0	592.0
07	970.0	10.0	7.0	12.0
08	11.0	2.0	16.0	970.0
09	5.0	3.0	666.0	325.0
10	10.0	930.0	35.0	24.0
11	844.0	32.0	3.0	120.0
12	411.0	26.0	215.0	347.0
13	471.0	66.0	389.0	73.0
14	333.0	112.0	154.0	400.0
15	178.0	223.0	402.0	196.0

PFM

	A	C	G	T
01	0.456	0.127	0.095	0.321
02	0.139	0.052	0.146	0.663
03	0.251	0.142	0.312	0.294
04	0.538	0.165	0.162	0.135
05	0.487	0.067	0.114	0.331
06	0.212	0.136	0.059	0.593
07	0.971	0.01	0.007	0.012
08	0.011	0.002	0.016	0.971
09	0.005	0.003	0.667	0.325
10	0.01	0.931	0.035	0.024
11	0.845	0.032	0.003	0.12
12	0.411	0.026	0.215	0.347
13	0.471	0.066	0.389	0.073
14	0.333	0.112	0.154	0.4
15	0.178	0.223	0.402	0.196

PWM

	A	C	G	T
01	0.599	-0.67	-0.955	0.249
02	-0.581	-1.543	-0.532	0.971
03	0.005	-0.559	0.221	0.162
04	0.762	-0.411	-0.429	-0.609
05	0.664	-1.297	-0.776	0.28
06	-0.163	-0.602	-1.421	0.859
07	1.352	-3.065	-3.361	-2.908
08	-2.984	-4.212	-2.652	1.352
09	-3.621	-3.974	0.977	0.262
10	-3.065	1.31	-1.924	-2.28
11	1.213	-2.009	-3.974	-0.726
12	0.495	-2.205	-0.149	0.327
13	0.631	-1.312	0.441	-1.214
14	0.286	-0.794	-0.479	0.468
15	-0.336	-0.112	0.473	-0.24

Standard thresholds

P-value	Threshold
0.001	4.68841
0.0005	5.58376
0.0001	7.34576