MotifPO3F1.H12INVITRO.3.M.C
Gene (human)POU3F1
(GeneCards)
Gene synonyms (human)OCT6, OTF6
Gene (mouse)Pou3f1
Gene synonyms (mouse)Oct6, Otf-6, Otf6, Scip
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
C
Motif length17
ConsensusndWTATGCTAATTARbn
GC content30.99%
Information content (bits; total / per base)18.227 / 1.072
Data sourcesMethyl-HT-SELEX
Aligned words3778

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (39) 0.608 0.794 0.418 0.648 0.549 0.772 1.5 2.269 4.481 59.398

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.979 0.972 0.923 0.91 0.835 0.816
best 0.998 0.997 0.982 0.977 0.934 0.923
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.982 0.977 0.934 0.923
best 0.998 0.997 0.982 0.977 0.934 0.923
Non-Methyl HT-SELEX, 3 experiments median 0.962 0.95 0.877 0.858 0.796 0.764
best 0.996 0.994 0.969 0.962 0.873 0.868
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPOU {3.1.10} (TFClass)
TF subfamilyPOU3 {3.1.10.3} (TFClass)
TFClass IDTFClass: 3.1.10.3.1
HGNCHGNC:9214
MGIMGI:101896
EntrezGene (human)GeneID:5453
(SSTAR profile)
EntrezGene (mouse)GeneID:18991
(SSTAR profile)
UniProt ID (human)PO3F1_HUMAN
UniProt ID (mouse)PO3F1_MOUSE
UniProt AC (human)Q03052
(TFClass)
UniProt AC (mouse)P21952
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011235.25979.25934.25629.25
021818.25548.25731.25680.25
03632.0114.0573.02459.0
04194.0264.069.03251.0
053442.057.0222.057.0
0634.0226.0172.03346.0
07225.0159.03390.04.0
08155.03063.097.0463.0
09770.00.03.03005.0
103778.00.00.00.0
113778.00.00.00.0
120.00.00.03778.0
133.014.01110.02651.0
143646.039.029.064.0
15567.0378.02638.0195.0
16473.01032.01411.0862.0
17661.0902.0750.01465.0
PFM
ACGT
010.3270.2590.2470.167
020.4810.1450.1940.18
030.1670.030.1520.651
040.0510.070.0180.861
050.9110.0150.0590.015
060.0090.060.0460.886
070.060.0420.8970.001
080.0410.8110.0260.123
090.2040.00.0010.795
101.00.00.00.0
111.00.00.00.0
120.00.00.01.0
130.0010.0040.2940.702
140.9650.010.0080.017
150.150.10.6980.052
160.1250.2730.3730.228
170.1750.2390.1990.388
PWM
ACGT
010.2680.036-0.011-0.405
020.654-0.542-0.255-0.327
03-0.401-2.099-0.4980.956
04-1.574-1.269-2.5891.235
051.292-2.774-1.441-2.774
06-3.268-1.423-1.6931.263
07-1.428-1.7711.276-5.051
08-1.7961.175-2.257-0.711
09-0.204-6.13-5.2321.156
101.385-6.13-6.13-6.13
111.385-6.13-6.13-6.13
12-6.13-6.13-6.131.385
13-5.232-4.0770.1611.031
141.349-3.138-3.417-2.662
15-0.509-0.9131.026-1.569
16-0.6890.0880.401-0.091
17-0.356-0.046-0.230.438
Standard thresholds
P-value Threshold
0.001 0.07531
0.0005 1.71436
0.0001 5.07316