| Motif | PO3F1.H12INVITRO.2.S.C |
| Gene (human) | POU3F1 (GeneCards) |
| Gene synonyms (human) | OCT6, OTF6 |
| Gene (mouse) | Pou3f1 |
| Gene synonyms (mouse) | Oct6, Otf-6, Otf6, Scip |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | C |
| Motif | PO3F1.H12INVITRO.2.S.C |
| Gene (human) | POU3F1 (GeneCards) |
| Gene synonyms (human) | OCT6, OTF6 |
| Gene (mouse) | Pou3f1 |
| Gene synonyms (mouse) | Oct6, Otf-6, Otf6, Scip |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | C |
| Motif length | 9 |
| Consensus | nTAATTMvn |
| GC content | 26.55% |
| Information content (bits; total / per base) | 9.362 / 1.04 |
| Data sources | HT-SELEX |
| Aligned words | 9399 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 6 (39) | 0.623 | 0.808 | 0.444 | 0.656 | 0.482 | 0.725 | 1.031 | 1.836 | 6.201 | 30.62 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.95 | 0.927 | 0.917 | 0.886 | 0.876 | 0.839 |
| best | 0.981 | 0.97 | 0.942 | 0.917 | 0.912 | 0.877 | |
| Methyl HT-SELEX, 1 experiments | median | 0.965 | 0.945 | 0.942 | 0.914 | 0.912 | 0.877 |
| best | 0.965 | 0.945 | 0.942 | 0.914 | 0.912 | 0.877 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.934 | 0.909 | 0.896 | 0.858 | 0.855 | 0.811 |
| best | 0.981 | 0.97 | 0.938 | 0.917 | 0.897 | 0.867 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | POU {3.1.10} (TFClass) |
| TF subfamily | POU3 {3.1.10.3} (TFClass) |
| TFClass ID | TFClass: 3.1.10.3.1 |
| HGNC | HGNC:9214 |
| MGI | MGI:101896 |
| EntrezGene (human) | GeneID:5453 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18991 (SSTAR profile) |
| UniProt ID (human) | PO3F1_HUMAN |
| UniProt ID (mouse) | PO3F1_MOUSE |
| UniProt AC (human) | Q03052 (TFClass) |
| UniProt AC (mouse) | P21952 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 6 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | PO3F1.H12INVITRO.2.S.C.pcm |
| PWM | PO3F1.H12INVITRO.2.S.C.pwm |
| PFM | PO3F1.H12INVITRO.2.S.C.pfm |
| Alignment | PO3F1.H12INVITRO.2.S.C.words.tsv |
| Threshold to P-value map | PO3F1.H12INVITRO.2.S.C.thr |
| Motif in other formats | |
| JASPAR format | PO3F1.H12INVITRO.2.S.C_jaspar_format.txt |
| MEME format | PO3F1.H12INVITRO.2.S.C_meme_format.meme |
| Transfac format | PO3F1.H12INVITRO.2.S.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2325.5 | 1842.5 | 2867.5 | 2363.5 |
| 02 | 14.0 | 45.0 | 43.0 | 9297.0 |
| 03 | 8687.0 | 0.0 | 712.0 | 0.0 |
| 04 | 9368.0 | 2.0 | 29.0 | 0.0 |
| 05 | 1.0 | 160.0 | 283.0 | 8955.0 |
| 06 | 23.0 | 0.0 | 3343.0 | 6033.0 |
| 07 | 7097.0 | 1160.0 | 464.0 | 678.0 |
| 08 | 2862.25 | 1463.25 | 4406.25 | 667.25 |
| 09 | 1569.0 | 3025.0 | 2615.0 | 2190.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.247 | 0.196 | 0.305 | 0.251 |
| 02 | 0.001 | 0.005 | 0.005 | 0.989 |
| 03 | 0.924 | 0.0 | 0.076 | 0.0 |
| 04 | 0.997 | 0.0 | 0.003 | 0.0 |
| 05 | 0.0 | 0.017 | 0.03 | 0.953 |
| 06 | 0.002 | 0.0 | 0.356 | 0.642 |
| 07 | 0.755 | 0.123 | 0.049 | 0.072 |
| 08 | 0.305 | 0.156 | 0.469 | 0.071 |
| 09 | 0.167 | 0.322 | 0.278 | 0.233 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.01 | -0.243 | 0.199 | 0.006 |
| 02 | -4.973 | -3.907 | -3.95 | 1.375 |
| 03 | 1.307 | -6.936 | -1.192 | -6.936 |
| 04 | 1.382 | -6.307 | -4.32 | -6.936 |
| 05 | -6.573 | -2.674 | -2.11 | 1.337 |
| 06 | -4.533 | -6.936 | 0.352 | 0.942 |
| 07 | 1.105 | -0.705 | -1.618 | -1.241 |
| 08 | 0.197 | -0.473 | 0.628 | -1.256 |
| 09 | -0.403 | 0.252 | 0.107 | -0.07 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.17008 |
| 0.0005 | 5.96333 |
| 0.0001 | 7.63749 |